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LTB4R (leukotriene B4 receptor)

Identity

Alias_namesP2RY7
GPR16
CMKRL1
Alias_symbol (synonym)BLTR
P2Y7
LTB4R1
Other aliasBLT1
LTBR1
HGNC (Hugo) LTB4R
LocusID (NCBI) 1241
Atlas_Id 45728
Location 14q12  [Link to chromosome band 14q12]
Location_base_pair Starts at 24311499 and ends at 24318036 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
COL1A2 (7q21.3) / LTB4R (14q12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LTB4R   6713
Cards
Entrez_Gene (NCBI)LTB4R  1241  leukotriene B4 receptor
AliasesBLT1; BLTR; CMKRL1; GPR16; 
LTB4R1; LTBR1; P2RY7; P2Y7
GeneCards (Weizmann)LTB4R
Ensembl hg19 (Hinxton)ENSG00000213903 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000213903 [Gene_View]  chr14:24311499-24318036 [Contig_View]  LTB4R [Vega]
ICGC DataPortalENSG00000213903
TCGA cBioPortalLTB4R
AceView (NCBI)LTB4R
Genatlas (Paris)LTB4R
WikiGenes1241
SOURCE (Princeton)LTB4R
Genetics Home Reference (NIH)LTB4R
Genomic and cartography
GoldenPath hg38 (UCSC)LTB4R  -     chr14:24311499-24318036 +  14q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LTB4R  -     14q12   [Description]    (hg19-Feb_2009)
EnsemblLTB4R - 14q12 [CytoView hg19]  LTB4R - 14q12 [CytoView hg38]
Mapping of homologs : NCBILTB4R [Mapview hg19]  LTB4R [Mapview hg38]
OMIM601531   
Gene and transcription
Genbank (Entrez)AA021034 AW242534 BC004545 BQ182452 BT007267
RefSeq transcript (Entrez)NM_001143919 NM_181657
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LTB4R
Cluster EST : UnigeneHs.567248 [ NCBI ]
CGAP (NCI)Hs.567248
Alternative Splicing GalleryENSG00000213903
Gene ExpressionLTB4R [ NCBI-GEO ]   LTB4R [ EBI - ARRAY_EXPRESS ]   LTB4R [ SEEK ]   LTB4R [ MEM ]
Gene Expression Viewer (FireBrowse)LTB4R [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1241
GTEX Portal (Tissue expression)LTB4R
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15722   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15722  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15722
Splice isoforms : SwissVarQ15722
PhosPhoSitePlusQ15722
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    Leukotriene_B4_rcpt    Leukotriene_B4_typ-1_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)LTB4R
DMDM Disease mutations1241
Blocks (Seattle)LTB4R
SuperfamilyQ15722
Human Protein AtlasENSG00000213903
Peptide AtlasQ15722
HPRD03320
IPIIPI00019382   IPI01025978   IPI01026261   
Protein Interaction databases
DIP (DOE-UCLA)Q15722
IntAct (EBI)Q15722
FunCoupENSG00000213903
BioGRIDLTB4R
STRING (EMBL)LTB4R
ZODIACLTB4R
Ontologies - Pathways
QuickGOQ15722
Ontology : AmiGOnucleotide binding  leukotriene B4 receptor activity  leukotriene receptor activity  plasma membrane  integral component of plasma membrane  movement of cell or subcellular component  muscle contraction  inflammatory response  immune response  G-protein coupled receptor signaling pathway  phospholipase C-activating G-protein coupled receptor signaling pathway  neuropeptide signaling pathway  G-protein coupled peptide receptor activity  membrane raft  leukotriene signaling pathway  
Ontology : EGO-EBInucleotide binding  leukotriene B4 receptor activity  leukotriene receptor activity  plasma membrane  integral component of plasma membrane  movement of cell or subcellular component  muscle contraction  inflammatory response  immune response  G-protein coupled receptor signaling pathway  phospholipase C-activating G-protein coupled receptor signaling pathway  neuropeptide signaling pathway  G-protein coupled peptide receptor activity  membrane raft  leukotriene signaling pathway  
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkLTB4R
Atlas of Cancer Signalling NetworkLTB4R
Wikipedia pathwaysLTB4R
Orthology - Evolution
OrthoDB1241
GeneTree (enSembl)ENSG00000213903
Phylogenetic Trees/Animal Genes : TreeFamLTB4R
HOVERGENQ15722
HOGENOMQ15722
Homologs : HomoloGeneLTB4R
Homology/Alignments : Family Browser (UCSC)LTB4R
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLTB4R [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LTB4R
dbVarLTB4R
ClinVarLTB4R
1000_GenomesLTB4R 
Exome Variant ServerLTB4R
ExAC (Exome Aggregation Consortium)LTB4R (select the gene name)
Genetic variants : HAPMAP1241
Genomic Variants (DGV)LTB4R [DGVbeta]
DECIPHERLTB4R [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLTB4R 
Mutations
ICGC Data PortalLTB4R 
TCGA Data PortalLTB4R 
Broad Tumor PortalLTB4R
OASIS PortalLTB4R [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLTB4R  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLTB4R
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LTB4R
DgiDB (Drug Gene Interaction Database)LTB4R
DoCM (Curated mutations)LTB4R (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LTB4R (select a term)
intoGenLTB4R
Cancer3DLTB4R(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601531   
Orphanet
MedgenLTB4R
Genetic Testing Registry LTB4R
NextProtQ15722 [Medical]
TSGene1241
GENETestsLTB4R
Huge Navigator LTB4R [HugePedia]
snp3D : Map Gene to Disease1241
BioCentury BCIQLTB4R
ClinGenLTB4R
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1241
Chemical/Pharm GKB GenePA30476
Clinical trialLTB4R
Miscellaneous
canSAR (ICR)LTB4R (select the gene name)
Probes
Litterature
PubMed66 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLTB4R
EVEXLTB4R
GoPubMedLTB4R
iHOPLTB4R
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:23:36 CEST 2017

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