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LTB4R2 (leukotriene B4 receptor 2)

Identity

Alias (NCBI)BLT2
BLTR2
JULF2
KPG_004
LTB4-R 2
LTB4-R2
NOP9
HGNC (Hugo) LTB4R2
HGNC Alias symbBLTR2
BLT2
JULF2
NOP9
LocusID (NCBI) 56413
Atlas_Id 43648
Location 14q12  [Link to chromosome band 14q12]
Location_base_pair Starts at 24310140 and ends at 24312038 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)LTB4R2   19260
Cards
Entrez_Gene (NCBI)LTB4R2    leukotriene B4 receptor 2
AliasesBLT2; BLTR2; JULF2; KPG_004; 
LTB4-R; LTB4-R2; NOP9
GeneCards (Weizmann)LTB4R2
Ensembl hg19 (Hinxton)ENSG00000213906 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000213906 [Gene_View]  ENSG00000213906 [Sequence]  chr14:24310140-24312038 [Contig_View]  LTB4R2 [Vega]
ICGC DataPortalENSG00000213906
TCGA cBioPortalLTB4R2
AceView (NCBI)LTB4R2
Genatlas (Paris)LTB4R2
SOURCE (Princeton)LTB4R2
Genetics Home Reference (NIH)LTB4R2
Genomic and cartography
GoldenPath hg38 (UCSC)LTB4R2  -     chr14:24310140-24312038 +  14q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LTB4R2  -     14q12   [Description]    (hg19-Feb_2009)
GoldenPathLTB4R2 - 14q12 [CytoView hg19]  LTB4R2 - 14q12 [CytoView hg38]
ImmunoBaseENSG00000213906
Genome Data Viewer NCBILTB4R2 [Mapview hg19]  
OMIM605773   
Gene and transcription
Genbank (Entrez)AB029892 AB032558 AB044402 AF277230 AF308571
RefSeq transcript (Entrez)NM_001164692 NM_001164693 NM_019839
Consensus coding sequences : CCDS (NCBI)LTB4R2
Gene ExpressionLTB4R2 [ NCBI-GEO ]   LTB4R2 [ EBI - ARRAY_EXPRESS ]   LTB4R2 [ SEEK ]   LTB4R2 [ MEM ]
Gene Expression Viewer (FireBrowse)LTB4R2 [ Firebrowse - Broad ]
GenevisibleExpression of LTB4R2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56413
GTEX Portal (Tissue expression)LTB4R2
Human Protein AtlasENSG00000213906-LTB4R2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NPC1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NPC1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NPC1
PhosPhoSitePlusQ9NPC1
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    Leukotriene_B4_rcpt    Leukotriene_B4_typ-2_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)LTB4R2
SuperfamilyQ9NPC1
AlphaFold pdb e-kbQ9NPC1   
Human Protein Atlas [tissue]ENSG00000213906-LTB4R2 [tissue]
HPRD16153
Protein Interaction databases
DIP (DOE-UCLA)Q9NPC1
IntAct (EBI)Q9NPC1
BioGRIDLTB4R2
STRING (EMBL)LTB4R2
ZODIACLTB4R2
Ontologies - Pathways
QuickGOQ9NPC1
Ontology : AmiGOleukotriene B4 receptor activity  leukotriene receptor activity  nucleoplasm  plasma membrane  plasma membrane  integral component of plasma membrane  chemotaxis  inflammatory response  G protein-coupled receptor signaling pathway  negative regulation of adenylate cyclase activity  neuropeptide signaling pathway  G protein-coupled peptide receptor activity  membrane  keratinocyte migration  leukotriene signaling pathway  
Ontology : EGO-EBIleukotriene B4 receptor activity  leukotriene receptor activity  nucleoplasm  plasma membrane  plasma membrane  integral component of plasma membrane  chemotaxis  inflammatory response  G protein-coupled receptor signaling pathway  negative regulation of adenylate cyclase activity  neuropeptide signaling pathway  G protein-coupled peptide receptor activity  membrane  keratinocyte migration  leukotriene signaling pathway  
Pathways : KEGGCalcium signaling pathway    Neuroactive ligand-receptor interaction   
NDEx NetworkLTB4R2
Atlas of Cancer Signalling NetworkLTB4R2
Wikipedia pathwaysLTB4R2
Orthology - Evolution
OrthoDB56413
GeneTree (enSembl)ENSG00000213906
Phylogenetic Trees/Animal Genes : TreeFamLTB4R2
Homologs : HomoloGeneLTB4R2
Homology/Alignments : Family Browser (UCSC)LTB4R2
Gene fusions - Rearrangements
Fusion : QuiverLTB4R2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLTB4R2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LTB4R2
dbVarLTB4R2
ClinVarLTB4R2
MonarchLTB4R2
1000_GenomesLTB4R2 
Exome Variant ServerLTB4R2
GNOMAD BrowserENSG00000213906
Varsome BrowserLTB4R2
ACMGLTB4R2 variants
VarityQ9NPC1
Genomic Variants (DGV)LTB4R2 [DGVbeta]
DECIPHERLTB4R2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLTB4R2 
Mutations
ICGC Data PortalLTB4R2 
TCGA Data PortalLTB4R2 
Broad Tumor PortalLTB4R2
OASIS PortalLTB4R2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLTB4R2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DLTB4R2
Mutations and Diseases : HGMDLTB4R2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaLTB4R2
DgiDB (Drug Gene Interaction Database)LTB4R2
DoCM (Curated mutations)LTB4R2
CIViC (Clinical Interpretations of Variants in Cancer)LTB4R2
Cancer3DLTB4R2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605773   
Orphanet
DisGeNETLTB4R2
MedgenLTB4R2
Genetic Testing Registry LTB4R2
NextProtQ9NPC1 [Medical]
GENETestsLTB4R2
Target ValidationLTB4R2
Huge Navigator LTB4R2 [HugePedia]
ClinGenLTB4R2
Clinical trials, drugs, therapy
MyCancerGenomeLTB4R2
Protein Interactions : CTDLTB4R2
Pharm GKB GenePA134910672
PharosQ9NPC1
Clinical trialLTB4R2
Miscellaneous
canSAR (ICR)LTB4R2
HarmonizomeLTB4R2
DataMed IndexLTB4R2
Probes
Litterature
PubMed58 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXLTB4R2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:17:14 CEST 2021

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