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LTBP1 (latent transforming growth factor beta binding protein 1)

Identity

Other names-
HGNC (Hugo) LTBP1
LocusID (NCBI) 4052
Location 2p22.3
Location_base_pair Starts at 33359664 and ends at 33624575 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)LTBP1   6714
Entrez_Gene (NCBI)LTBP1  4052  latent transforming growth factor beta binding protein 1
Cards
GeneCards (Weizmann)LTBP1
Ensembl (Hinxton)ENSG00000049323 [Gene_View]  chr2:33359664-33624575 [Contig_View]  LTBP1 [Vega]
AceView (NCBI)LTBP1
Genatlas (Paris)LTBP1
SOURCE (Stanford)NM_000627 NM_001166264 NM_001166265 NM_001166266 NM_206943
Genomic and cartography
GoldenPath (UCSC)LTBP1  -  2p22.3   chr2:33359664-33624575 +  2p22.3   [Description]    (hg19-Feb_2009)
EnsemblLTBP1 - 2p22.3 [CytoView]
Mapping of homologs : NCBILTBP1 [Mapview]
OMIM150390   
Gene and transcription
Genbank (Entrez)AA935267 AB208801 AF489528 AK298027 AK299237
RefSeq transcript (SRS)NM_000627 NM_001166264 NM_001166265 NM_001166266 NM_206943
RefSeq transcript (Entrez)NM_000627 NM_001166264 NM_001166265 NM_001166266 NM_206943
RefSeq genomic (SRS)AC_000134 NC_000002 NC_018913 NT_022184 NW_001838769 NW_004078005
RefSeq genomic (Entrez)AC_000134 NC_000002 NC_018913 NT_022184 NW_001838769 NW_004078005
Consensus coding sequences : CCDS (NCBI)LTBP1
Cluster EST : UnigeneHs.619315 [ SRS ] Hs.619315 [ NCBI ]
CGAP (NCI)Hs.619315
Alternative Splicing : Fast-db (Paris)GSHG0016370
Alternative Splicing GalleryENSG00000049323
Gene ExpressionLTBP1 [ NCBI-GEO ]   LTBP1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14766 (SRS) Q14766 (Uniprot)
NextProtQ14766
With graphics : InterProQ14766
Splice isoforms : SwissVarQ14766(Swissvar)
Domaine pattern : Prosite (SRS)ASX_HYDROXYL (PS00010)    EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    EGF_CA (PS01187)    TB (PS51364)   
Domaine pattern : Prosite (Expaxy)ASX_HYDROXYL (PS00010)    EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    EGF_CA (PS01187)    TB (PS51364)   
Domains : Interpro (SRS)EG-like_dom    EGF-like_Ca-bd    EGF-like_CS    EGF-type_Asp/Asn_hydroxyl_site    EGF_Ca-bd_CS    TB_dom   
Domains : Interpro (EBI)EG-like_dom    EGF-like_Ca-bd    EGF-like_CS    EGF-type_Asp/Asn_hydroxyl_site    EGF_Ca-bd_CS    TB_dom   
Related proteins : CluSTrQ14766
Domain families : Pfam (SRS)EGF_CA (PF07645)    TB (PF00683)   
Domain families : Pfam (Sanger)EGF_CA (PF07645)    TB (PF00683)   
Domain families : Pfam (NCBI)pfam07645    pfam00683   
Domain families : Smart (EMBL)EGF (SM00181)  EGF_CA (SM00179)  
DMDM4052
Blocks (Seattle)Q14766
PDB (SRS)1KSQ   
PDB (PDBSum)1KSQ   
PDB (IMB)1KSQ   
PDB (RSDB)1KSQ   
Human Protein AtlasENSG00000049323
HPRD01039
IPIIPI00784258   IPI00302679   IPI00894247   IPI00973177   IPI00973086   IPI00220249   IPI00929158   IPI00893273   IPI00893975   IPI00893279   IPI00893543   IPI00893691   
Protein Interaction databases
DIP (DOE-UCLA)Q14766
IntAct (EBI)Q14766
FunCoupENSG00000049323
REACTOMELTBP1
Protein Interaction Database4052
BioGRIDLTBP1
InParanoidQ14766
Interologous Interaction database Q14766
IntegromeDBLTBP1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)LTBP1
SNP (GeneSNP Utah)LTBP1
SNP : HGBaseLTBP1
Genetic variants : HAPMAPLTBP1
Somatic Mutations in Cancer : COSMICLTBP1 
CONAN: Copy Number AnalysisLTBP1 
Mutations and Diseases : HGMDLTBP1
OMIM150390   
GENETests150390   
Disease Genetic AssociationLTBP1
Huge Navigator LTBP1 [HugePedia]  LTBP1 [HugeCancerGEM]
Genomic VariantsLTBP1  LTBP1 [DGVbeta]
snp3D : Map Gene to Disease4052
General knowledge
Homologs : HomoloGeneLTBP1
Homology/Alignments : Family Browser (UCSC)LTBP1
Phylogenetic Trees/Animal Genes : TreeFamLTBP1
Chemical/Protein Interactions : CTD4052
Chemical/Pharm GKB GenePA30477
Clinical trialLTBP1
Cancer Resource (Charite)ENSG00000049323
Ontology : AmiGOtransforming growth factor beta-activated receptor activity  calcium ion binding  protein binding  proteinaceous extracellular matrix  growth factor binding  extracellular matrix  sequestering of TGFbeta in extracellular matrix  
Ontology : EGO-EBItransforming growth factor beta-activated receptor activity  calcium ion binding  protein binding  proteinaceous extracellular matrix  growth factor binding  extracellular matrix  sequestering of TGFbeta in extracellular matrix  
Pathways : KEGGTGF-beta signaling pathway
Other databases
Probes
Litterature
PubMed54 Pubmed reference(s) in Entrez
PubGeneLTBP1
iHOPLTBP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:41:42 CEST 2013
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