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LTBP2 (latent transforming growth factor beta binding protein 2)

Identity

Alias_namesLTBP3
C14orf141
chromosome 14 open reading frame 141
Other aliasGLC3D
MSPKA
MSTP031
WMS3
HGNC (Hugo) LTBP2
LocusID (NCBI) 4053
Atlas_Id 41213
Location 14q24.3  [Link to chromosome band 14q24]
Location_base_pair Starts at 74498183 and ends at 74612331 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LTBP2 (14q24.3) / CYB561 (17q23.3)LTBP2 (14q24.3) / LTBP2 (14q24.3)LTBP2 (14q24.3) / PLCB2 (15q15.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LTBP2   6715
Cards
Entrez_Gene (NCBI)LTBP2  4053  latent transforming growth factor beta binding protein 2
AliasesC14orf141; GLC3D; LTBP3; MSPKA; 
MSTP031; WMS3
GeneCards (Weizmann)LTBP2
Ensembl hg19 (Hinxton)ENSG00000119681 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000119681 [Gene_View]  chr14:74498183-74612331 [Contig_View]  LTBP2 [Vega]
ICGC DataPortalENSG00000119681
TCGA cBioPortalLTBP2
AceView (NCBI)LTBP2
Genatlas (Paris)LTBP2
WikiGenes4053
SOURCE (Princeton)LTBP2
Genetics Home Reference (NIH)LTBP2
Genomic and cartography
GoldenPath hg38 (UCSC)LTBP2  -     chr14:74498183-74612331 -  14q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LTBP2  -     14q24.3   [Description]    (hg19-Feb_2009)
EnsemblLTBP2 - 14q24.3 [CytoView hg19]  LTBP2 - 14q24.3 [CytoView hg38]
Mapping of homologs : NCBILTBP2 [Mapview hg19]  LTBP2 [Mapview hg38]
OMIM251750   600975   602091   613086   614819   
Gene and transcription
Genbank (Entrez)AB209865 AF113211 BC032434 BC047742 BC062686
RefSeq transcript (Entrez)NM_000428
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LTBP2
Cluster EST : UnigeneHs.597522 [ NCBI ]
CGAP (NCI)Hs.597522
Alternative Splicing GalleryENSG00000119681
Gene ExpressionLTBP2 [ NCBI-GEO ]   LTBP2 [ EBI - ARRAY_EXPRESS ]   LTBP2 [ SEEK ]   LTBP2 [ MEM ]
Gene Expression Viewer (FireBrowse)LTBP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4053
GTEX Portal (Tissue expression)LTBP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14767   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14767  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14767
Splice isoforms : SwissVarQ14767
PhosPhoSitePlusQ14767
Domaine pattern : Prosite (Expaxy)ASX_HYDROXYL (PS00010)    EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    EGF_CA (PS01187)    TB (PS51364)   
Domains : Interpro (EBI)EGF-like_Ca-bd_dom    EGF-like_CS    EGF-like_dom    EGF-type_Asp/Asn_hydroxyl_site    EGF_Ca-bd_CS    Growth_fac_rcpt_    TB_dom   
Domain families : Pfam (Sanger)EGF (PF00008)    EGF_CA (PF07645)    TB (PF00683)   
Domain families : Pfam (NCBI)pfam00008    pfam07645    pfam00683   
Domain families : Smart (EMBL)EGF (SM00181)  EGF_CA (SM00179)  
Conserved Domain (NCBI)LTBP2
DMDM Disease mutations4053
Blocks (Seattle)LTBP2
SuperfamilyQ14767
Human Protein AtlasENSG00000119681
Peptide AtlasQ14767
HPRD03650
IPIIPI00292150   IPI00012482   IPI01025450   IPI01025298   IPI01025308   IPI01025396   
Protein Interaction databases
DIP (DOE-UCLA)Q14767
IntAct (EBI)Q14767
FunCoupENSG00000119681
BioGRIDLTBP2
STRING (EMBL)LTBP2
ZODIACLTBP2
Ontologies - Pathways
QuickGOQ14767
Ontology : AmiGOcalcium ion binding  protein binding  proteinaceous extracellular matrix  extracellular space  intracellular  protein targeting  transforming growth factor beta receptor signaling pathway  heparin binding  protein secretion  growth factor binding  extracellular matrix  extracellular exosome  supramolecular fiber organization  
Ontology : EGO-EBIcalcium ion binding  protein binding  proteinaceous extracellular matrix  extracellular space  intracellular  protein targeting  transforming growth factor beta receptor signaling pathway  heparin binding  protein secretion  growth factor binding  extracellular matrix  extracellular exosome  supramolecular fiber organization  
NDEx NetworkLTBP2
Atlas of Cancer Signalling NetworkLTBP2
Wikipedia pathwaysLTBP2
Orthology - Evolution
OrthoDB4053
GeneTree (enSembl)ENSG00000119681
Phylogenetic Trees/Animal Genes : TreeFamLTBP2
HOVERGENQ14767
HOGENOMQ14767
Homologs : HomoloGeneLTBP2
Homology/Alignments : Family Browser (UCSC)LTBP2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLTBP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LTBP2
dbVarLTBP2
ClinVarLTBP2
1000_GenomesLTBP2 
Exome Variant ServerLTBP2
ExAC (Exome Aggregation Consortium)LTBP2 (select the gene name)
Genetic variants : HAPMAP4053
Genomic Variants (DGV)LTBP2 [DGVbeta]
DECIPHERLTBP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLTBP2 
Mutations
ICGC Data PortalLTBP2 
TCGA Data PortalLTBP2 
Broad Tumor PortalLTBP2
OASIS PortalLTBP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLTBP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLTBP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
BioMutasearch LTBP2
DgiDB (Drug Gene Interaction Database)LTBP2
DoCM (Curated mutations)LTBP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LTBP2 (select a term)
intoGenLTBP2
Cancer3DLTBP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM251750    600975    602091    613086    614819   
Orphanet3033    19302    13993   
MedgenLTBP2
Genetic Testing Registry LTBP2
NextProtQ14767 [Medical]
TSGene4053
GENETestsLTBP2
Target ValidationLTBP2
Huge Navigator LTBP2 [HugePedia]
snp3D : Map Gene to Disease4053
BioCentury BCIQLTBP2
ClinGenLTBP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4053
Chemical/Pharm GKB GenePA164741922
Clinical trialLTBP2
Miscellaneous
canSAR (ICR)LTBP2 (select the gene name)
Probes
Litterature
PubMed64 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLTBP2
EVEXLTBP2
GoPubMedLTBP2
iHOPLTBP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:16:38 CEST 2017

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