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LTBP4 (latent transforming growth factor beta binding protein 4)

Identity

Other namesARCL1C
LTBP-4
LTBP4L
LTBP4S
HGNC (Hugo) LTBP4
LocusID (NCBI) 8425
Location 19q13.2
Location_base_pair Starts at 41103141 and ends at 41135725 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)LTBP4   6717
Cards
Entrez_Gene (NCBI)LTBP4  8425  latent transforming growth factor beta binding protein 4
GeneCards (Weizmann)LTBP4
Ensembl (Hinxton)ENSG00000090006 [Gene_View]  chr19:41103141-41135725 [Contig_View]  LTBP4 [Vega]
ICGC DataPortalENSG00000090006
AceView (NCBI)LTBP4
Genatlas (Paris)LTBP4
WikiGenes8425
SOURCE (Princeton)NM_001042544 NM_001042545 NM_003573
Genomic and cartography
GoldenPath (UCSC)LTBP4  -  19q13.2   chr19:41103141-41135725 +  19q13.2   [Description]    (hg19-Feb_2009)
EnsemblLTBP4 - 19q13.2 [CytoView]
Mapping of homologs : NCBILTBP4 [Mapview]
OMIM604710   613177   
Gene and transcription
Genbank (Entrez)AF051344 AF051345 AF054501 AF054502 AK074499
RefSeq transcript (Entrez)NM_001042544 NM_001042545 NM_003573
RefSeq genomic (Entrez)AC_000151 NC_000019 NC_018930 NG_021201 NT_011109 NW_001838496 NW_004929415
Consensus coding sequences : CCDS (NCBI)LTBP4
Cluster EST : UnigeneHs.466766 [ NCBI ]
CGAP (NCI)Hs.466766
Alternative Splicing : Fast-db (Paris)GSHG0014932
Alternative Splicing GalleryENSG00000090006
Gene ExpressionLTBP4 [ NCBI-GEO ]     LTBP4 [ SEEK ]   LTBP4 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N2S1 (Uniprot)
NextProtQ8N2S1  [Medical]
With graphics : InterProQ8N2S1
Splice isoforms : SwissVarQ8N2S1 (Swissvar)
Domaine pattern : Prosite (Expaxy)ASX_HYDROXYL (PS00010)    EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    EGF_CA (PS01187)    TB (PS51364)   
Domains : Interpro (EBI)cEGF    EG-like_dom    EGF-like_Ca-bd_dom    EGF-like_CS    EGF-type_Asp/Asn_hydroxyl_site    EGF_Ca-bd_CS    Growth_fac_rcpt_N_dom    TB_dom   
Related proteins : CluSTrQ8N2S1
Domain families : Pfam (Sanger)cEGF (PF12662)    EGF_CA (PF07645)    TB (PF00683)   
Domain families : Pfam (NCBI)pfam12662    pfam07645    pfam00683   
Domain families : Smart (EMBL)EGF (SM00181)  EGF_CA (SM00179)  
DMDM Disease mutations8425
Blocks (Seattle)Q8N2S1
Human Protein AtlasENSG00000090006
Peptide AtlasQ8N2S1
HPRD05274
IPIIPI00873371   IPI00783492   IPI00792792   IPI00395783   IPI00921901   IPI01018340   IPI01014061   IPI00025732   
Protein Interaction databases
DIP (DOE-UCLA)Q8N2S1
IntAct (EBI)Q8N2S1
FunCoupENSG00000090006
BioGRIDLTBP4
IntegromeDBLTBP4
STRING (EMBL)LTBP4
Ontologies - Pathways
QuickGOQ8N2S1
Ontology : AmiGOregulation of cell growth  transforming growth factor beta-activated receptor activity  integrin binding  calcium ion binding  protein binding  glycosaminoglycan binding  extracellular region  proteinaceous extracellular matrix  extracellular space  protein folding  transforming growth factor beta receptor signaling pathway  multicellular organismal development  regulation of transforming growth factor beta receptor signaling pathway  regulation of proteolysis  extracellular matrix organization  growth hormone secretion  extracellular matrix  extracellular matrix  regulation of cell differentiation  transforming growth factor beta binding  transforming growth factor beta binding  extracellular vesicular exosome  
Ontology : EGO-EBIregulation of cell growth  transforming growth factor beta-activated receptor activity  integrin binding  calcium ion binding  protein binding  glycosaminoglycan binding  extracellular region  proteinaceous extracellular matrix  extracellular space  protein folding  transforming growth factor beta receptor signaling pathway  multicellular organismal development  regulation of transforming growth factor beta receptor signaling pathway  regulation of proteolysis  extracellular matrix organization  growth hormone secretion  extracellular matrix  extracellular matrix  regulation of cell differentiation  transforming growth factor beta binding  transforming growth factor beta binding  extracellular vesicular exosome  
Protein Interaction DatabaseLTBP4
Wikipedia pathwaysLTBP4
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)LTBP4
SNP (GeneSNP Utah)LTBP4
SNP : HGBaseLTBP4
Genetic variants : HAPMAPLTBP4
1000_GenomesLTBP4 
ICGC programENSG00000090006 
CONAN: Copy Number AnalysisLTBP4 
Somatic Mutations in Cancer : COSMICLTBP4 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
DECIPHER (Syndromes)19:41103141-41135725
Mutations and Diseases : HGMDLTBP4
OMIM604710    613177   
MedgenLTBP4
GENETestsLTBP4
Disease Genetic AssociationLTBP4
Huge Navigator LTBP4 [HugePedia]  LTBP4 [HugeCancerGEM]
Genomic VariantsLTBP4  LTBP4 [DGVbeta]
Exome VariantLTBP4
dbVarLTBP4
ClinVarLTBP4
snp3D : Map Gene to Disease8425
General knowledge
Homologs : HomoloGeneLTBP4
Homology/Alignments : Family Browser (UCSC)LTBP4
Phylogenetic Trees/Animal Genes : TreeFamLTBP4
Chemical/Protein Interactions : CTD8425
Chemical/Pharm GKB GenePA30480
Clinical trialLTBP4
Cancer Resource (Charite)ENSG00000090006
Other databases
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
CoreMineLTBP4
GoPubMedLTBP4
iHOPLTBP4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Nov 8 17:38:49 CET 2014

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