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LTBP4 (latent transforming growth factor beta binding protein 4)

Identity

Other namesLTBP-4
LTBP4L
LTBP4S
HGNC (Hugo) LTBP4
LocusID (NCBI) 8425
Location 19q13.2
Location_base_pair Starts at 41103141 and ends at 41135725 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)LTBP4   6717
Entrez_Gene (NCBI)LTBP4  8425  latent transforming growth factor beta binding protein 4
Cards
GeneCards (Weizmann)LTBP4
Ensembl (Hinxton)ENSG00000090006 [Gene_View]  chr19:41103141-41135725 [Contig_View]  LTBP4 [Vega]
AceView (NCBI)LTBP4
Genatlas (Paris)LTBP4
SOURCE (Stanford)NM_001042544 NM_001042545 NM_003573
Genomic and cartography
GoldenPath (UCSC)LTBP4  -  19q13.2   chr19:41103141-41135725 +  19q13.2   [Description]    (hg19-Feb_2009)
EnsemblLTBP4 - 19q13.2 [CytoView]
Mapping of homologs : NCBILTBP4 [Mapview]
OMIM604710   613177   
Gene and transcription
Genbank (Entrez)AF051344 AF051345 AF054501 AF054502 AK074499
RefSeq transcript (SRS)NM_001042544 NM_001042545 NM_003573
RefSeq transcript (Entrez)NM_001042544 NM_001042545 NM_003573
RefSeq genomic (SRS)AC_000151 NC_000019 NC_018930 NG_021201 NT_011109 NW_001838496 NW_004078099
RefSeq genomic (Entrez)AC_000151 NC_000019 NC_018930 NG_021201 NT_011109 NW_001838496 NW_004078099
Consensus coding sequences : CCDS (NCBI)LTBP4
Cluster EST : UnigeneHs.466766 [ SRS ] Hs.466766 [ NCBI ]
CGAP (NCI)Hs.466766
Alternative Splicing : Fast-db (Paris)GSHG0014932
Alternative Splicing GalleryENSG00000090006
Gene ExpressionLTBP4 [ NCBI-GEO ]   LTBP4 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N2S1 (SRS) Q8N2S1 (Uniprot)
NextProtQ8N2S1
With graphics : InterProQ8N2S1
Splice isoforms : SwissVarQ8N2S1(Swissvar)
Domaine pattern : Prosite (SRS)ASX_HYDROXYL (PS00010)    EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    EGF_CA (PS01187)    TB (PS51364)   
Domaine pattern : Prosite (Expaxy)ASX_HYDROXYL (PS00010)    EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)    EGF_CA (PS01187)    TB (PS51364)   
Domains : Interpro (SRS)EG-like_dom    EGF-like_Ca-bd    EGF-like_CS    EGF-type_Asp/Asn_hydroxyl_site    EGF_Ca-bd_CS    TB_dom   
Domains : Interpro (EBI)EG-like_dom    EGF-like_Ca-bd    EGF-like_CS    EGF-type_Asp/Asn_hydroxyl_site    EGF_Ca-bd_CS    TB_dom   
Related proteins : CluSTrQ8N2S1
Domain families : Pfam (SRS)EGF_CA (PF07645)    TB (PF00683)   
Domain families : Pfam (Sanger)EGF_CA (PF07645)    TB (PF00683)   
Domain families : Pfam (NCBI)pfam07645    pfam00683   
Domain families : Smart (EMBL)EGF (SM00181)  EGF_CA (SM00179)  
DMDM8425
Blocks (Seattle)Q8N2S1
Human Protein AtlasENSG00000090006
HPRD05274
IPIIPI00873371   IPI00783492   IPI00792792   IPI00395783   IPI00921901   IPI01018340   IPI01014061   IPI00025732   
Protein Interaction databases
DIP (DOE-UCLA)Q8N2S1
IntAct (EBI)Q8N2S1
FunCoupENSG00000090006
REACTOMELTBP4
Protein Interaction Database8425
BioGRIDLTBP4
InParanoidQ8N2S1
Interologous Interaction database Q8N2S1
IntegromeDBLTBP4
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)LTBP4
SNP (GeneSNP Utah)LTBP4
SNP : HGBaseLTBP4
Genetic variants : HAPMAPLTBP4
Somatic Mutations in Cancer : COSMICLTBP4 
CONAN: Copy Number AnalysisLTBP4 
Mutations and Diseases : HGMDLTBP4
OMIM604710    613177   
GENETests604710    613177   
Disease Genetic AssociationLTBP4
Huge Navigator LTBP4 [HugePedia]  LTBP4 [HugeCancerGEM]
Genomic VariantsLTBP4  LTBP4 [DGVbeta]
snp3D : Map Gene to Disease8425
General knowledge
Homologs : HomoloGeneLTBP4
Homology/Alignments : Family Browser (UCSC)LTBP4
Phylogenetic Trees/Animal Genes : TreeFamLTBP4
Chemical/Protein Interactions : CTD8425
Chemical/Pharm GKB GenePA30480
Clinical trialLTBP4
Cancer Resource (Charite)ENSG00000090006
Ontology : AmiGOregulation of cell growth  transforming growth factor beta-activated receptor activity  integrin binding  calcium ion binding  protein binding  glycosaminoglycan binding  proteinaceous extracellular matrix  extracellular space  protein folding  transforming growth factor beta receptor signaling pathway  multicellular organismal development  regulation of transforming growth factor beta receptor signaling pathway  regulation of proteolysis  growth hormone secretion  extracellular matrix  regulation of cell differentiation  transforming growth factor beta binding  
Ontology : EGO-EBIregulation of cell growth  transforming growth factor beta-activated receptor activity  integrin binding  calcium ion binding  protein binding  glycosaminoglycan binding  proteinaceous extracellular matrix  extracellular space  protein folding  transforming growth factor beta receptor signaling pathway  multicellular organismal development  regulation of transforming growth factor beta receptor signaling pathway  regulation of proteolysis  growth hormone secretion  extracellular matrix  regulation of cell differentiation  transforming growth factor beta binding  
Other databases
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
PubGeneLTBP4
iHOPLTBP4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:41:49 CEST 2013
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