Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

LTBR (lymphotoxin beta receptor)

Identity

Other namesCD18
D12S370
LT-BETA-R
TNF-R-III
TNFCR
TNFR-RP
TNFR2-RP
TNFR3
TNFRSF3
HGNC (Hugo) LTBR
LocusID (NCBI) 4055
Atlas_Id 41216
Location 12p13.31
Location_base_pair Starts at 6484534 and ends at 6500737 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LTBR   6718
Cards
Entrez_Gene (NCBI)LTBR  4055  lymphotoxin beta receptor
GeneCards (Weizmann)LTBR
Ensembl hg19 (Hinxton)ENSG00000111321 [Gene_View]  chr12:6484534-6500737 [Contig_View]  LTBR [Vega]
Ensembl hg38 (Hinxton)ENSG00000111321 [Gene_View]  chr12:6484534-6500737 [Contig_View]  LTBR [Vega]
ICGC DataPortalENSG00000111321
TCGA cBioPortalLTBR
AceView (NCBI)LTBR
Genatlas (Paris)LTBR
WikiGenes4055
SOURCE (Princeton)LTBR
Genomic and cartography
GoldenPath hg19 (UCSC)LTBR  -     chr12:6484534-6500737 +  12p13.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LTBR  -     12p13.31   [Description]    (hg38-Dec_2013)
EnsemblLTBR - 12p13.31 [CytoView hg19]  LTBR - 12p13.31 [CytoView hg38]
Mapping of homologs : NCBILTBR [Mapview hg19]  LTBR [Mapview hg38]
OMIM600979   
Gene and transcription
Genbank (Entrez)AK027080 AK095418 AK128019 AK293187 BC026262
RefSeq transcript (Entrez)NM_001270987 NM_002342
RefSeq genomic (Entrez)NC_000012 NC_018923 NG_033039 NT_009759 NW_004929382
Consensus coding sequences : CCDS (NCBI)LTBR
Cluster EST : UnigeneHs.1116 [ NCBI ]
CGAP (NCI)Hs.1116
Alternative Splicing : Fast-db (Paris)GSHG0006409
Alternative Splicing GalleryENSG00000111321
Gene ExpressionLTBR [ NCBI-GEO ]     LTBR [ SEEK ]   LTBR [ MEM ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)4055
Protein : pattern, domain, 3D structure
UniProt/SwissProtP36941 (Uniprot)
NextProtP36941  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP36941
Splice isoforms : SwissVarP36941 (Swissvar)
PhosPhoSitePlusP36941
Domaine pattern : Prosite (Expaxy)TNFR_NGFR_1 (PS00652)    TNFR_NGFR_2 (PS50050)   
Domains : Interpro (EBI)TNFR/NGFR_Cys_rich_reg    TNFR_3_LTBR   
Domain families : Pfam (Sanger)TNFR_c6 (PF00020)   
Domain families : Pfam (NCBI)pfam00020   
Domain families : Smart (EMBL)TNFR (SM00208)  
DMDM Disease mutations4055
Blocks (Seattle)LTBR
PDB (SRS)1RF3    4MXW   
PDB (PDBSum)1RF3    4MXW   
PDB (IMB)1RF3    4MXW   
PDB (RSDB)1RF3    4MXW   
Structural Biology KnowledgeBase1RF3    4MXW   
SCOP (Structural Classification of Proteins)1RF3    4MXW   
CATH (Classification of proteins structures)1RF3    4MXW   
Human Protein AtlasENSG00000111321
Peptide AtlasP36941
HPRD02988
IPIIPI00006097   IPI01014882   IPI00977977   IPI01015852   IPI01014968   IPI00789031   IPI01014258   IPI01013824   
Protein Interaction databases
DIP (DOE-UCLA)P36941
IntAct (EBI)P36941
FunCoupENSG00000111321
BioGRIDLTBR
IntegromeDBLTBR
STRING (EMBL)LTBR
ZODIACLTBR
Ontologies - Pathways
QuickGOP36941
Ontology : AmiGOtumor necrosis factor-activated receptor activity  protein binding  plasma membrane  integral component of plasma membrane  inflammatory response  immune response  signal transduction  multicellular organismal development  viral process  ubiquitin protein ligase binding  response to lipopolysaccharide  tumor necrosis factor-mediated signaling pathway  regulation of cell proliferation  identical protein binding  myeloid dendritic cell differentiation  positive regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of JNK cascade  cellular response to mechanical stimulus  apoptotic signaling pathway  positive regulation of extrinsic apoptotic signaling pathway  
Ontology : EGO-EBItumor necrosis factor-activated receptor activity  protein binding  plasma membrane  integral component of plasma membrane  inflammatory response  immune response  signal transduction  multicellular organismal development  viral process  ubiquitin protein ligase binding  response to lipopolysaccharide  tumor necrosis factor-mediated signaling pathway  regulation of cell proliferation  identical protein binding  myeloid dendritic cell differentiation  positive regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of JNK cascade  cellular response to mechanical stimulus  apoptotic signaling pathway  positive regulation of extrinsic apoptotic signaling pathway  
Pathways : KEGGCytokine-cytokine receptor interaction    NF-kappa B signaling pathway    HIF-1 signaling pathway    Intestinal immune network for IgA production    HTLV-I infection    Viral carcinogenesis   
Protein Interaction DatabaseLTBR
Atlas of Cancer Signalling NetworkLTBR
Wikipedia pathwaysLTBR
Orthology - Evolution
OrthoDB4055
GeneTree (enSembl)ENSG00000111321
Phylogenetic Trees/Animal Genes : TreeFamLTBR
Homologs : HomoloGeneLTBR
Homology/Alignments : Family Browser (UCSC)LTBR
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerLTBR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LTBR
dbVarLTBR
ClinVarLTBR
1000_GenomesLTBR 
Exome Variant ServerLTBR
Exome Aggregation Consortium (ExAC)ENSG00000111321
SNP (GeneSNP Utah)LTBR
SNP : HGBaseLTBR
Genetic variants : HAPMAPLTBR
Genomic Variants (DGV)LTBR [DGVbeta]
Mutations
ICGC Data PortalLTBR 
TCGA Data PortalLTBR 
Tumor PortalLTBR
TCGA Copy Number PortalLTBR
Somatic Mutations in Cancer : COSMICLTBR 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LTBR
DgiDB (Drug Gene Interaction Database)LTBR
DoCM (Curated mutations)LTBR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LTBR (select a term)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)12:6484534-6500737
CONAN: Copy Number AnalysisLTBR 
Mutations and Diseases : HGMDLTBR
OMIM600979   
MedgenLTBR
NextProtP36941 [Medical]
TSGene4055
GENETestsLTBR
Huge Navigator LTBR [HugePedia]  LTBR [HugeCancerGEM]
snp3D : Map Gene to Disease4055
BioCentury BCIQLTBR
General knowledge
Chemical/Protein Interactions : CTD4055
Chemical/Pharm GKB GenePA30481
Clinical trialLTBR
Other databases
Probes
Litterature
PubMed85 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLTBR
GoPubMedLTBR
iHOPLTBR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jan 16 18:57:33 CET 2016

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.