Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

URGENT NEED of MONEY :
GO to the page SAVE the Atlas and DONATE

LTBR (lymphotoxin beta receptor (TNFR superfamily, member 3))

Identity

Other namesCD18
D12S370
LT-BETA-R
TNF-R-III
TNFCR
TNFR-RP
TNFR2-RP
TNFR3
TNFRSF3
HGNC (Hugo) LTBR
LocusID (NCBI) 4055
Atlas_Id 41216
Location 12p13.31
Location_base_pair Starts at 6484534 and ends at 6500737 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)LTBR   6718
Cards
Entrez_Gene (NCBI)LTBR  4055  lymphotoxin beta receptor (TNFR superfamily, member 3)
GeneCards (Weizmann)LTBR
Ensembl hg19 (Hinxton)ENSG00000111321 [Gene_View]  chr12:6484534-6500737 [Contig_View]  LTBR [Vega]
Ensembl hg38 (Hinxton)ENSG00000111321 [Gene_View]  chr12:6484534-6500737 [Contig_View]  LTBR [Vega]
ICGC DataPortalENSG00000111321
TCGA cBioPortalLTBR
AceView (NCBI)LTBR
Genatlas (Paris)LTBR
WikiGenes4055
SOURCE (Princeton)LTBR
Genomic and cartography
GoldenPath hg19 (UCSC)LTBR  -     chr12:6484534-6500737 +  12p13.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LTBR  -     12p13.31   [Description]    (hg38-Dec_2013)
EnsemblLTBR - 12p13.31 [CytoView hg19]  LTBR - 12p13.31 [CytoView hg38]
Mapping of homologs : NCBILTBR [Mapview hg19]  LTBR [Mapview hg38]
OMIM600979   
Gene and transcription
Genbank (Entrez)AK027080 AK095418 AK128019 AK293187 BC026262
RefSeq transcript (Entrez)NM_001270987 NM_002342
RefSeq genomic (Entrez)NC_000012 NC_018923 NG_033039 NT_009759 NW_004929382
Consensus coding sequences : CCDS (NCBI)LTBR
Cluster EST : UnigeneHs.1116 [ NCBI ]
CGAP (NCI)Hs.1116
Alternative Splicing : Fast-db (Paris)GSHG0006409
Alternative Splicing GalleryENSG00000111321
Gene ExpressionLTBR [ NCBI-GEO ]     LTBR [ SEEK ]   LTBR [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP36941 (Uniprot)
NextProtP36941  [Medical]
With graphics : InterProP36941
Splice isoforms : SwissVarP36941 (Swissvar)
Domaine pattern : Prosite (Expaxy)TNFR_NGFR_1 (PS00652)    TNFR_NGFR_2 (PS50050)   
Domains : Interpro (EBI)TNFR/NGFR_Cys_rich_reg    TNFR_3_LTBR   
Related proteins : CluSTrP36941
Domain families : Pfam (Sanger)TNFR_c6 (PF00020)   
Domain families : Pfam (NCBI)pfam00020   
Domain families : Smart (EMBL)TNFR (SM00208)  
DMDM Disease mutations4055
Blocks (Seattle)P36941
PDB (SRS)1RF3    4MXW   
PDB (PDBSum)1RF3    4MXW   
PDB (IMB)1RF3    4MXW   
PDB (RSDB)1RF3    4MXW   
Human Protein AtlasENSG00000111321
Peptide AtlasP36941
HPRD02988
IPIIPI00006097   IPI01014882   IPI00977977   IPI01015852   IPI01014968   IPI00789031   IPI01014258   IPI01013824   
Protein Interaction databases
DIP (DOE-UCLA)P36941
IntAct (EBI)P36941
FunCoupENSG00000111321
BioGRIDLTBR
IntegromeDBLTBR
STRING (EMBL)LTBR
Ontologies - Pathways
QuickGOP36941
Ontology : AmiGOprotein binding  apoptotic process  signal transduction  integral component of membrane  viral process  ubiquitin protein ligase binding  identical protein binding  myeloid dendritic cell differentiation  positive regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of JNK cascade  cellular response to mechanical stimulus  positive regulation of extrinsic apoptotic signaling pathway  
Ontology : EGO-EBIprotein binding  apoptotic process  signal transduction  integral component of membrane  viral process  ubiquitin protein ligase binding  identical protein binding  myeloid dendritic cell differentiation  positive regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of JNK cascade  cellular response to mechanical stimulus  positive regulation of extrinsic apoptotic signaling pathway  
Pathways : KEGGCytokine-cytokine receptor interaction    NF-kappa B signaling pathway    HIF-1 signaling pathway    Intestinal immune network for IgA production    HTLV-I infection    Viral carcinogenesis   
Protein Interaction DatabaseLTBR
DoCM (Curated mutations)LTBR
Wikipedia pathwaysLTBR
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerLTBR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LTBR
dbVarLTBR
ClinVarLTBR
1000_GenomesLTBR 
Exome Variant ServerLTBR
SNP (GeneSNP Utah)LTBR
SNP : HGBaseLTBR
Genetic variants : HAPMAPLTBR
Genomic Variants (DGV)LTBR [DGVbeta]
Mutations
ICGC Data PortalLTBR 
TCGA Data PortalLTBR 
Tumor PortalLTBR
Somatic Mutations in Cancer : COSMICLTBR 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)12:6484534-6500737
CONAN: Copy Number AnalysisLTBR 
Mutations and Diseases : HGMDLTBR
OMIM600979   
MedgenLTBR
NextProtP36941 [Medical]
GENETestsLTBR
Disease Genetic AssociationLTBR
Huge Navigator LTBR [HugePedia]  LTBR [HugeCancerGEM]
snp3D : Map Gene to Disease4055
DGIdb (Drug Gene Interaction db)LTBR
General knowledge
Homologs : HomoloGeneLTBR
Homology/Alignments : Family Browser (UCSC)LTBR
Phylogenetic Trees/Animal Genes : TreeFamLTBR
Chemical/Protein Interactions : CTD4055
Chemical/Pharm GKB GenePA30481
Clinical trialLTBR
Cancer Resource (Charite)ENSG00000111321
Other databases
Probes
Litterature
PubMed85 Pubmed reference(s) in Entrez
CoreMineLTBR
GoPubMedLTBR
iHOPLTBR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 20 19:35:28 CEST 2015

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.