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LTN1 (listerin E3 ubiquitin protein ligase 1)

Identity

Alias_namesC21orf98
C21orf10
ZNF294
RNF160
chromosome 21 open reading frame 98
zinc finger protein 294
ring finger protein 160
Alias_symbol (synonym)KIAA0714
FLJ11053
LISTERIN
Other alias
HGNC (Hugo) LTN1
LocusID (NCBI) 26046
Atlas_Id 68696
Location 21q21.3  [Link to chromosome band 21q21]
Location_base_pair Starts at 28928145 and ends at 28992959 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LTN1 (21q21.3) / RWDD2B (21q21.3)LTN1 (21q21.3) / TIAM1 (21q22.11)SLC37A1 (21q22.3) / LTN1 (21q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LTN1   13082
Cards
Entrez_Gene (NCBI)LTN1  26046  listerin E3 ubiquitin protein ligase 1
AliasesC21orf10; C21orf98; RNF160; ZNF294
GeneCards (Weizmann)LTN1
Ensembl hg19 (Hinxton)ENSG00000198862 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198862 [Gene_View]  chr21:28928145-28992959 [Contig_View]  LTN1 [Vega]
ICGC DataPortalENSG00000198862
TCGA cBioPortalLTN1
AceView (NCBI)LTN1
Genatlas (Paris)LTN1
WikiGenes26046
SOURCE (Princeton)LTN1
Genetics Home Reference (NIH)LTN1
Genomic and cartography
GoldenPath hg38 (UCSC)LTN1  -     chr21:28928145-28992959 -  21q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LTN1  -     21q21.3   [Description]    (hg19-Feb_2009)
EnsemblLTN1 - 21q21.3 [CytoView hg19]  LTN1 - 21q21.3 [CytoView hg38]
Mapping of homologs : NCBILTN1 [Mapview hg19]  LTN1 [Mapview hg38]
OMIM613083   
Gene and transcription
Genbank (Entrez)AB018257 AB621822 AF161350 AI279340 AK001915
RefSeq transcript (Entrez)NM_001320766 NM_015565
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LTN1
Cluster EST : UnigeneHs.288773 [ NCBI ]
CGAP (NCI)Hs.288773
Alternative Splicing GalleryENSG00000198862
Gene ExpressionLTN1 [ NCBI-GEO ]   LTN1 [ EBI - ARRAY_EXPRESS ]   LTN1 [ SEEK ]   LTN1 [ MEM ]
Gene Expression Viewer (FireBrowse)LTN1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26046
GTEX Portal (Tissue expression)LTN1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO94822   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO94822  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO94822
Splice isoforms : SwissVarO94822
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   
PhosPhoSitePlusO94822
Domaine pattern : Prosite (Expaxy)ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)ARM-type_fold    Znf_RING    Znf_RING-CH    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)zf-RING_2 (PF13639)   
Domain families : Pfam (NCBI)pfam13639   
Domain families : Smart (EMBL)RINGv (SM00744)  
Conserved Domain (NCBI)LTN1
DMDM Disease mutations26046
Blocks (Seattle)LTN1
PDB (SRS)3J92   
PDB (PDBSum)3J92   
PDB (IMB)3J92   
PDB (RSDB)3J92   
Structural Biology KnowledgeBase3J92   
SCOP (Structural Classification of Proteins)3J92   
CATH (Classification of proteins structures)3J92   
SuperfamilyO94822
Human Protein AtlasENSG00000198862
Peptide AtlasO94822
HPRD10327
IPIIPI01012824   IPI00942336   IPI00783835   IPI00793009   
Protein Interaction databases
DIP (DOE-UCLA)O94822
IntAct (EBI)O94822
FunCoupENSG00000198862
BioGRIDLTN1
STRING (EMBL)LTN1
ZODIACLTN1
Ontologies - Pathways
QuickGOO94822
Ontology : AmiGOprotein binding  zinc ion binding  protein autoubiquitination  ubiquitin protein ligase activity  
Ontology : EGO-EBIprotein binding  zinc ion binding  protein autoubiquitination  ubiquitin protein ligase activity  
NDEx NetworkLTN1
Atlas of Cancer Signalling NetworkLTN1
Wikipedia pathwaysLTN1
Orthology - Evolution
OrthoDB26046
GeneTree (enSembl)ENSG00000198862
Phylogenetic Trees/Animal Genes : TreeFamLTN1
HOVERGENO94822
HOGENOMO94822
Homologs : HomoloGeneLTN1
Homology/Alignments : Family Browser (UCSC)LTN1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLTN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LTN1
dbVarLTN1
ClinVarLTN1
1000_GenomesLTN1 
Exome Variant ServerLTN1
ExAC (Exome Aggregation Consortium)LTN1 (select the gene name)
Genetic variants : HAPMAP26046
Genomic Variants (DGV)LTN1 [DGVbeta]
DECIPHERLTN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLTN1 
Mutations
ICGC Data PortalLTN1 
TCGA Data PortalLTN1 
Broad Tumor PortalLTN1
OASIS PortalLTN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLTN1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLTN1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LTN1
DgiDB (Drug Gene Interaction Database)LTN1
DoCM (Curated mutations)LTN1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LTN1 (select a term)
intoGenLTN1
Cancer3DLTN1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613083   
Orphanet
MedgenLTN1
Genetic Testing Registry LTN1
NextProtO94822 [Medical]
TSGene26046
GENETestsLTN1
Target ValidationLTN1
Huge Navigator LTN1 [HugePedia]
snp3D : Map Gene to Disease26046
BioCentury BCIQLTN1
ClinGenLTN1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26046
Chemical/Pharm GKB GenePA37658
Clinical trialLTN1
Miscellaneous
canSAR (ICR)LTN1 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLTN1
EVEXLTN1
GoPubMedLTN1
iHOPLTN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:26:41 CEST 2017

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