Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

LXN (latexin)

Identity

Alias (NCBI)ECI
TCI
HGNC (Hugo) LXN
LocusID (NCBI) 56925
Atlas_Id 52304
Location 3q25.32  [Link to chromosome band 3q25]
Location_base_pair Starts at 158666414 and ends at 158672648 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TBL1XR1 (3q26.32) / LXN (3q25.32)TBL1XR1 3q26.32 / LXN 3q25.32

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)LXN   13347
Cards
Entrez_Gene (NCBI)LXN    latexin
AliasesECI; TCI
GeneCards (Weizmann)LXN
Ensembl hg19 (Hinxton)ENSG00000079257 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000079257 [Gene_View]  ENSG00000079257 [Sequence]  chr3:158666414-158672648 [Contig_View]  LXN [Vega]
ICGC DataPortalENSG00000079257
TCGA cBioPortalLXN
AceView (NCBI)LXN
Genatlas (Paris)LXN
SOURCE (Princeton)LXN
Genetics Home Reference (NIH)LXN
Genomic and cartography
GoldenPath hg38 (UCSC)LXN  -     chr3:158666414-158672648 -  3q25.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LXN  -     3q25.32   [Description]    (hg19-Feb_2009)
GoldenPathLXN - 3q25.32 [CytoView hg19]  LXN - 3q25.32 [CytoView hg38]
ImmunoBaseENSG00000079257
Genome Data Viewer NCBILXN [Mapview hg19]  
OMIM609305   
Gene and transcription
Genbank (Entrez)AF087851 AF282594 AF282626 BC005346 BC008438
RefSeq transcript (Entrez)NM_020169
Consensus coding sequences : CCDS (NCBI)LXN
Gene ExpressionLXN [ NCBI-GEO ]   LXN [ EBI - ARRAY_EXPRESS ]   LXN [ SEEK ]   LXN [ MEM ]
Gene Expression Viewer (FireBrowse)LXN [ Firebrowse - Broad ]
GenevisibleExpression of LXN in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56925
GTEX Portal (Tissue expression)LXN
Human Protein AtlasENSG00000079257-LXN [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BS40   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BS40  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BS40
PhosPhoSitePlusQ9BS40
Domains : Interpro (EBI)Prot_inh_latexin   
Domain families : Pfam (Sanger)Latexin (PF06907)   
Domain families : Pfam (NCBI)pfam06907   
Conserved Domain (NCBI)LXN
PDB (RSDB)2BO9   
PDB Europe2BO9   
PDB (PDBSum)2BO9   
PDB (IMB)2BO9   
Structural Biology KnowledgeBase2BO9   
SCOP (Structural Classification of Proteins)2BO9   
CATH (Classification of proteins structures)2BO9   
SuperfamilyQ9BS40
AlphaFold pdb e-kbQ9BS40   
Human Protein Atlas [tissue]ENSG00000079257-LXN [tissue]
HPRD14327
Protein Interaction databases
DIP (DOE-UCLA)Q9BS40
IntAct (EBI)Q9BS40
BioGRIDLXN
STRING (EMBL)LXN
ZODIACLXN
Ontologies - Pathways
QuickGOQ9BS40
Ontology : AmiGOprotein binding  extracellular space  cytoplasm  inflammatory response  metalloendopeptidase inhibitor activity  heparin binding  negative regulation of endopeptidase activity  detection of temperature stimulus involved in sensory perception of pain  
Ontology : EGO-EBIprotein binding  extracellular space  cytoplasm  inflammatory response  metalloendopeptidase inhibitor activity  heparin binding  negative regulation of endopeptidase activity  detection of temperature stimulus involved in sensory perception of pain  
NDEx NetworkLXN
Atlas of Cancer Signalling NetworkLXN
Wikipedia pathwaysLXN
Orthology - Evolution
OrthoDB56925
GeneTree (enSembl)ENSG00000079257
Phylogenetic Trees/Animal Genes : TreeFamLXN
Homologs : HomoloGeneLXN
Homology/Alignments : Family Browser (UCSC)LXN
Gene fusions - Rearrangements
Fusion : MitelmanTBL1XR1/LXN [3q26.32/3q25.32]  
Fusion : QuiverLXN
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLXN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LXN
dbVarLXN
ClinVarLXN
MonarchLXN
1000_GenomesLXN 
Exome Variant ServerLXN
GNOMAD BrowserENSG00000079257
Varsome BrowserLXN
ACMGLXN variants
VarityQ9BS40
Genomic Variants (DGV)LXN [DGVbeta]
DECIPHERLXN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLXN 
Mutations
ICGC Data PortalLXN 
TCGA Data PortalLXN 
Broad Tumor PortalLXN
OASIS PortalLXN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLXN  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DLXN
Mutations and Diseases : HGMDLXN
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaLXN
DgiDB (Drug Gene Interaction Database)LXN
DoCM (Curated mutations)LXN
CIViC (Clinical Interpretations of Variants in Cancer)LXN
Cancer3DLXN
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609305   
Orphanet
DisGeNETLXN
MedgenLXN
Genetic Testing Registry LXN
NextProtQ9BS40 [Medical]
GENETestsLXN
Target ValidationLXN
Huge Navigator LXN [HugePedia]
ClinGenLXN
Clinical trials, drugs, therapy
MyCancerGenomeLXN
Protein Interactions : CTDLXN
Pharm GKB GenePA134991999
PharosQ9BS40
Clinical trialLXN
Miscellaneous
canSAR (ICR)LXN
HarmonizomeLXN
DataMed IndexLXN
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXLXN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:17:17 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.