LXN (latexin)

2011-08-01  

Identity

HGNC
LOCATION
3q25.32
LOCUSID
ALIAS
ECI,TCI
FUSION GENES

Other Information

Locus ID:

NCBI: 56925
MIM: 609305
HGNC: 13347
Ensembl: ENSG00000079257

Variants:

dbSNP: 56925
ClinVar: 56925
TCGA: ENSG00000079257
COSMIC: LXN

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000079257ENST00000264265Q9BS40
ENSG00000079257ENST00000482640H7C5A4

Expression (GTEx)

0
10
20
30
40
50
60
70

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
233644792013The hematopoietic stem cell regulatory gene latexin has tumor-suppressive properties in malignant melanoma.18
214667062011Latexin expression is downregulated in human gastric carcinomas and exhibits tumor suppressor potential.17
215674032012Latexin regulates the abundance of multiple cellular proteins in hematopoietic stem cells.14
243992462014Latexin exhibits tumor suppressor potential in hepatocellular carcinoma.10
230287172012Latexin is down-regulated in hematopoietic malignancies and restoration of expression inhibits lymphoma growth.9
237127062013Clinical significance of CD146 and latexin during different stages of thyroid cancer.5
265305302016Latexin exhibits tumor-suppressor potential in pancreatic ductal adenocarcinoma.3
280877402017Bone Microenvironment Changes in Latexin Expression Promote Chemoresistance.3
255514722014Latexin inhibits the proliferation of CD133+ miapaca-2 pancreatic cancer stem-like cells.2
296084882018Latexin and hematopoiesis.0

Citation

Dessen P

LXN (latexin)

Atlas Genet Cytogenet Oncol Haematol. 2011-08-01

Online version: http://atlasgeneticsoncology.org/gene/52304/lxn