Atlas of Genetics and Cytogenetics in Oncology and Haematology


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LXN (latexin)

Identity

Other aliasECI
TCI
HGNC (Hugo) LXN
LocusID (NCBI) 56925
Atlas_Id 52304
Location 3q25.32  [Link to chromosome band 3q25]
Location_base_pair Starts at 158384203 and ends at 158390482 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
TBL1XR1 (3q26.32) / LXN (3q25.32)TBL1XR1 3q26.32 / LXN 3q25.32

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LXN   13347
Cards
Entrez_Gene (NCBI)LXN  56925  latexin
AliasesECI; TCI
GeneCards (Weizmann)LXN
Ensembl hg19 (Hinxton)ENSG00000079257 [Gene_View]  chr3:158384203-158390482 [Contig_View]  LXN [Vega]
Ensembl hg38 (Hinxton)ENSG00000079257 [Gene_View]  chr3:158384203-158390482 [Contig_View]  LXN [Vega]
ICGC DataPortalENSG00000079257
TCGA cBioPortalLXN
AceView (NCBI)LXN
Genatlas (Paris)LXN
WikiGenes56925
SOURCE (Princeton)LXN
Genetics Home Reference (NIH)LXN
Genomic and cartography
GoldenPath hg19 (UCSC)LXN  -     chr3:158384203-158390482 -  3q25.32   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LXN  -     3q25.32   [Description]    (hg38-Dec_2013)
EnsemblLXN - 3q25.32 [CytoView hg19]  LXN - 3q25.32 [CytoView hg38]
Mapping of homologs : NCBILXN [Mapview hg19]  LXN [Mapview hg38]
OMIM609305   
Gene and transcription
Genbank (Entrez)AF087851 AF282594 AF282626 BC005346 BC008438
RefSeq transcript (Entrez)NM_020169
RefSeq genomic (Entrez)NC_000003 NC_018914 NG_008441 NT_005612 NW_004929311
Consensus coding sequences : CCDS (NCBI)LXN
Cluster EST : UnigeneHs.478067 [ NCBI ]
CGAP (NCI)Hs.478067
Alternative Splicing GalleryENSG00000079257
Gene ExpressionLXN [ NCBI-GEO ]   LXN [ EBI - ARRAY_EXPRESS ]   LXN [ SEEK ]   LXN [ MEM ]
Gene Expression Viewer (FireBrowse)LXN [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56925
GTEX Portal (Tissue expression)LXN
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BS40   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BS40  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BS40
Splice isoforms : SwissVarQ9BS40
PhosPhoSitePlusQ9BS40
Domains : Interpro (EBI)Prot_inh_latexin   
Domain families : Pfam (Sanger)Latexin (PF06907)   
Domain families : Pfam (NCBI)pfam06907   
Domain structure : Prodom (Prabi Lyon)Prot_inh_latexin (PD023134)   
Conserved Domain (NCBI)LXN
DMDM Disease mutations56925
Blocks (Seattle)LXN
PDB (SRS)2BO9   
PDB (PDBSum)2BO9   
PDB (IMB)2BO9   
PDB (RSDB)2BO9   
Structural Biology KnowledgeBase2BO9   
SCOP (Structural Classification of Proteins)2BO9   
CATH (Classification of proteins structures)2BO9   
SuperfamilyQ9BS40
Human Protein AtlasENSG00000079257
Peptide AtlasQ9BS40
HPRD14327
IPIIPI00106687   IPI00796699   
Protein Interaction databases
DIP (DOE-UCLA)Q9BS40
IntAct (EBI)Q9BS40
FunCoupENSG00000079257
BioGRIDLXN
STRING (EMBL)LXN
ZODIACLXN
Ontologies - Pathways
QuickGOQ9BS40
Ontology : AmiGOprotein binding  cytoplasm  inflammatory response  metalloendopeptidase inhibitor activity  heparin binding  negative regulation of endopeptidase activity  detection of temperature stimulus involved in sensory perception of pain  extracellular exosome  
Ontology : EGO-EBIprotein binding  cytoplasm  inflammatory response  metalloendopeptidase inhibitor activity  heparin binding  negative regulation of endopeptidase activity  detection of temperature stimulus involved in sensory perception of pain  extracellular exosome  
NDEx NetworkLXN
Atlas of Cancer Signalling NetworkLXN
Wikipedia pathwaysLXN
Orthology - Evolution
OrthoDB56925
GeneTree (enSembl)ENSG00000079257
Phylogenetic Trees/Animal Genes : TreeFamLXN
HOVERGENQ9BS40
HOGENOMQ9BS40
Homologs : HomoloGeneLXN
Homology/Alignments : Family Browser (UCSC)LXN
Gene fusions - Rearrangements
Fusion : MitelmanTBL1XR1/LXN [3q26.32/3q25.32]  [t(3;3)(q25;q26)]  
Fusion: TCGATBL1XR1 3q26.32 LXN 3q25.32 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLXN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LXN
dbVarLXN
ClinVarLXN
1000_GenomesLXN 
Exome Variant ServerLXN
ExAC (Exome Aggregation Consortium)LXN (select the gene name)
Genetic variants : HAPMAP56925
Genomic Variants (DGV)LXN [DGVbeta]
DECIPHER (Syndromes)3:158384203-158390482  ENSG00000079257
CONAN: Copy Number AnalysisLXN 
Mutations
ICGC Data PortalLXN 
TCGA Data PortalLXN 
Broad Tumor PortalLXN
OASIS PortalLXN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLXN  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLXN
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LXN
DgiDB (Drug Gene Interaction Database)LXN
DoCM (Curated mutations)LXN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LXN (select a term)
intoGenLXN
Cancer3DLXN(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609305   
Orphanet
MedgenLXN
Genetic Testing Registry LXN
NextProtQ9BS40 [Medical]
TSGene56925
GENETestsLXN
Huge Navigator LXN [HugePedia]
snp3D : Map Gene to Disease56925
BioCentury BCIQLXN
ClinGenLXN
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56925
Chemical/Pharm GKB GenePA134991999
Clinical trialLXN
Miscellaneous
canSAR (ICR)LXN (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLXN
EVEXLXN
GoPubMedLXN
iHOPLXN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:08:05 CEST 2017

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