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LY6E (lymphocyte antigen 6 family member E)

Identity

Alias (NCBI)RIG-E
RIGE
SCA-2
SCA2
TSA-1
HGNC (Hugo) LY6E
HGNC Alias symbTSA-1
RIG-E
SCA-2
HGNC Alias nameretinoic acid induced gene E
HGNC Previous namelymphocyte antigen 6 complex, locus E
LocusID (NCBI) 4061
Atlas_Id 41220
Location 8q24.3  [Link to chromosome band 8q24]
Location_base_pair Starts at 143018529 and ends at 143022409 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LY6E (8q24.3) / COL15A1 (9q22.33)LY6E (8q24.3) / LY6E (8q24.3)LY6E (8q24.3) / ZNF511 (10q26.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)LY6E   6727
Cards
Entrez_Gene (NCBI)LY6E    lymphocyte antigen 6 family member E
AliasesRIG-E; RIGE; SCA-2; SCA2; 
TSA-1
GeneCards (Weizmann)LY6E
Ensembl hg19 (Hinxton)ENSG00000160932 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000160932 [Gene_View]  ENSG00000160932 [Sequence]  chr8:143018529-143022409 [Contig_View]  LY6E [Vega]
ICGC DataPortalENSG00000160932
TCGA cBioPortalLY6E
AceView (NCBI)LY6E
Genatlas (Paris)LY6E
SOURCE (Princeton)LY6E
Genetics Home Reference (NIH)LY6E
Genomic and cartography
GoldenPath hg38 (UCSC)LY6E  -     chr8:143018529-143022409 +  8q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LY6E  -     8q24.3   [Description]    (hg19-Feb_2009)
GoldenPathLY6E - 8q24.3 [CytoView hg19]  LY6E - 8q24.3 [CytoView hg38]
ImmunoBaseENSG00000160932
Genome Data Viewer NCBILY6E [Mapview hg19]  
OMIM601384   
Gene and transcription
Genbank (Entrez)AF085875 AK129615 AK223074 AK311983 BC003392
RefSeq transcript (Entrez)NM_001127213 NM_002346
Consensus coding sequences : CCDS (NCBI)LY6E
Gene ExpressionLY6E [ NCBI-GEO ]   LY6E [ EBI - ARRAY_EXPRESS ]   LY6E [ SEEK ]   LY6E [ MEM ]
Gene Expression Viewer (FireBrowse)LY6E [ Firebrowse - Broad ]
GenevisibleExpression of LY6E in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4061
GTEX Portal (Tissue expression)LY6E
Human Protein AtlasENSG00000160932-LY6E [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16553   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16553  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16553
PhosPhoSitePlusQ16553
Domains : Interpro (EBI)LY6_UPA_recep-like   
Domain families : Pfam (Sanger)UPAR_LY6 (PF00021)   
Domain families : Pfam (NCBI)pfam00021   
Domain families : Smart (EMBL)LU (SM00134)  
Conserved Domain (NCBI)LY6E
SuperfamilyQ16553
AlphaFold pdb e-kbQ16553   
Human Protein Atlas [tissue]ENSG00000160932-LY6E [tissue]
HPRD03227
Protein Interaction databases
DIP (DOE-UCLA)Q16553
IntAct (EBI)Q16553
BioGRIDLY6E
STRING (EMBL)LY6E
ZODIACLY6E
Ontologies - Pathways
QuickGOQ16553
Ontology : AmiGOin utero embryonic development  protein binding  extracellular region  plasma membrane  plasma membrane  cell surface receptor signaling pathway  adrenal gland development  acetylcholine receptor inhibitor activity  anchored component of membrane  acetylcholine receptor binding  organ growth  norepinephrine metabolic process  synapse  negative regulation of viral entry into host cell  epinephrine secretion  ventricular cardiac muscle tissue morphogenesis  acetylcholine receptor signaling pathway  negative regulation of signaling receptor activity  
Ontology : EGO-EBIin utero embryonic development  protein binding  extracellular region  plasma membrane  plasma membrane  cell surface receptor signaling pathway  adrenal gland development  acetylcholine receptor inhibitor activity  anchored component of membrane  acetylcholine receptor binding  organ growth  norepinephrine metabolic process  synapse  negative regulation of viral entry into host cell  epinephrine secretion  ventricular cardiac muscle tissue morphogenesis  acetylcholine receptor signaling pathway  negative regulation of signaling receptor activity  
NDEx NetworkLY6E
Atlas of Cancer Signalling NetworkLY6E
Wikipedia pathwaysLY6E
Orthology - Evolution
OrthoDB4061
GeneTree (enSembl)ENSG00000160932
Phylogenetic Trees/Animal Genes : TreeFamLY6E
Homologs : HomoloGeneLY6E
Homology/Alignments : Family Browser (UCSC)LY6E
Gene fusions - Rearrangements
Fusion : QuiverLY6E
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLY6E [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LY6E
dbVarLY6E
ClinVarLY6E
MonarchLY6E
1000_GenomesLY6E 
Exome Variant ServerLY6E
GNOMAD BrowserENSG00000160932
Varsome BrowserLY6E
ACMGLY6E variants
VarityQ16553
Genomic Variants (DGV)LY6E [DGVbeta]
DECIPHERLY6E [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLY6E 
Mutations
ICGC Data PortalLY6E 
TCGA Data PortalLY6E 
Broad Tumor PortalLY6E
OASIS PortalLY6E [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLY6E  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DLY6E
Mutations and Diseases : HGMDLY6E
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaLY6E
DgiDB (Drug Gene Interaction Database)LY6E
DoCM (Curated mutations)LY6E
CIViC (Clinical Interpretations of Variants in Cancer)LY6E
Cancer3DLY6E
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601384   
Orphanet
DisGeNETLY6E
MedgenLY6E
Genetic Testing Registry LY6E
NextProtQ16553 [Medical]
GENETestsLY6E
Target ValidationLY6E
Huge Navigator LY6E [HugePedia]
ClinGenLY6E
Clinical trials, drugs, therapy
MyCancerGenomeLY6E
Protein Interactions : CTDLY6E
Pharm GKB GenePA30491
PharosQ16553
Clinical trialLY6E
Miscellaneous
canSAR (ICR)LY6E
HarmonizomeLY6E
DataMed IndexLY6E
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXLY6E
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:17:17 CEST 2021

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