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LY6E (lymphocyte antigen 6 family member E)

Identity

Alias_symbol (synonym)TSA-1
RIG-E
SCA-2
Other aliasRIGE
SCA2
HGNC (Hugo) LY6E
LocusID (NCBI) 4061
Atlas_Id 41220
Location 8q24.3  [Link to chromosome band 8q24]
Location_base_pair Starts at 143018485 and ends at 143022410 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LY6E (8q24.3) / COL15A1 (9q22.33)LY6E (8q24.3) / LY6E (8q24.3)LY6E (8q24.3) / ZNF511 (10q26.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LY6E   6727
Cards
Entrez_Gene (NCBI)LY6E  4061  lymphocyte antigen 6 family member E
AliasesRIG-E; RIGE; SCA-2; SCA2; 
TSA-1
GeneCards (Weizmann)LY6E
Ensembl hg19 (Hinxton)ENSG00000160932 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000160932 [Gene_View]  chr8:143018485-143022410 [Contig_View]  LY6E [Vega]
ICGC DataPortalENSG00000160932
TCGA cBioPortalLY6E
AceView (NCBI)LY6E
Genatlas (Paris)LY6E
WikiGenes4061
SOURCE (Princeton)LY6E
Genetics Home Reference (NIH)LY6E
Genomic and cartography
GoldenPath hg38 (UCSC)LY6E  -     chr8:143018485-143022410 +  8q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LY6E  -     8q24.3   [Description]    (hg19-Feb_2009)
EnsemblLY6E - 8q24.3 [CytoView hg19]  LY6E - 8q24.3 [CytoView hg38]
Mapping of homologs : NCBILY6E [Mapview hg19]  LY6E [Mapview hg38]
OMIM601384   
Gene and transcription
Genbank (Entrez)AF085875 AK129615 AK223074 AK311983 BC003392
RefSeq transcript (Entrez)NM_001127213 NM_002346
RefSeq genomic (Entrez)NC_000008 NC_018919 NT_187573
Consensus coding sequences : CCDS (NCBI)LY6E
Cluster EST : UnigeneHs.521903 [ NCBI ]
CGAP (NCI)Hs.521903
Alternative Splicing GalleryENSG00000160932
Gene ExpressionLY6E [ NCBI-GEO ]   LY6E [ EBI - ARRAY_EXPRESS ]   LY6E [ SEEK ]   LY6E [ MEM ]
Gene Expression Viewer (FireBrowse)LY6E [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4061
GTEX Portal (Tissue expression)LY6E
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16553   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16553  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16553
Splice isoforms : SwissVarQ16553
PhosPhoSitePlusQ16553
Domains : Interpro (EBI)LY6_UPA_recep-like   
Domain families : Pfam (Sanger)UPAR_LY6 (PF00021)   
Domain families : Pfam (NCBI)pfam00021   
Domain families : Smart (EMBL)LU (SM00134)  
Conserved Domain (NCBI)LY6E
DMDM Disease mutations4061
Blocks (Seattle)LY6E
SuperfamilyQ16553
Human Protein AtlasENSG00000160932
Peptide AtlasQ16553
HPRD03227
IPIIPI00002899   IPI00974417   IPI00979994   IPI01014592   IPI00797693   IPI00793398   
Protein Interaction databases
DIP (DOE-UCLA)Q16553
IntAct (EBI)Q16553
FunCoupENSG00000160932
BioGRIDLY6E
STRING (EMBL)LY6E
ZODIACLY6E
Ontologies - Pathways
QuickGOQ16553
Ontology : AmiGOextracellular region  plasma membrane  integral component of plasma membrane  C-terminal protein lipidation  cell surface receptor signaling pathway  anchored component of membrane  
Ontology : EGO-EBIextracellular region  plasma membrane  integral component of plasma membrane  C-terminal protein lipidation  cell surface receptor signaling pathway  anchored component of membrane  
NDEx NetworkLY6E
Atlas of Cancer Signalling NetworkLY6E
Wikipedia pathwaysLY6E
Orthology - Evolution
OrthoDB4061
GeneTree (enSembl)ENSG00000160932
Phylogenetic Trees/Animal Genes : TreeFamLY6E
HOVERGENQ16553
HOGENOMQ16553
Homologs : HomoloGeneLY6E
Homology/Alignments : Family Browser (UCSC)LY6E
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLY6E [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LY6E
dbVarLY6E
ClinVarLY6E
1000_GenomesLY6E 
Exome Variant ServerLY6E
ExAC (Exome Aggregation Consortium)LY6E (select the gene name)
Genetic variants : HAPMAP4061
Genomic Variants (DGV)LY6E [DGVbeta]
DECIPHERLY6E [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLY6E 
Mutations
ICGC Data PortalLY6E 
TCGA Data PortalLY6E 
Broad Tumor PortalLY6E
OASIS PortalLY6E [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLY6E  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLY6E
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LY6E
DgiDB (Drug Gene Interaction Database)LY6E
DoCM (Curated mutations)LY6E (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LY6E (select a term)
intoGenLY6E
Cancer3DLY6E(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601384   
Orphanet
MedgenLY6E
Genetic Testing Registry LY6E
NextProtQ16553 [Medical]
TSGene4061
GENETestsLY6E
Target ValidationLY6E
Huge Navigator LY6E [HugePedia]
snp3D : Map Gene to Disease4061
BioCentury BCIQLY6E
ClinGenLY6E
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4061
Chemical/Pharm GKB GenePA30491
Clinical trialLY6E
Miscellaneous
canSAR (ICR)LY6E (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLY6E
EVEXLY6E
GoPubMedLY6E
iHOPLY6E
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:16:42 CEST 2017

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