LY6G6D (lymphocyte antigen 6 family member G6D)

2019-04-01  

Identity

HGNC
LY6G6D
LOCATION
6p21.33
LOCUSID
58530
ALIAS
C6orf23,G6D,LY6-D,MEGT1,NG25

Other Information

Locus ID:

NCBI: 58530
MIM: 606038
HGNC: 13935
Ensembl: ENSG00000244355

Variants:

dbSNP: 58530
ClinVar: 58530
TCGA: ENSG00000244355
COSMIC: LY6G6D

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000244355ENST00000375824F6XWZ1
ENSG00000244355ENST00000375824Q8NDY2
ENSG00000244355ENST00000375825O95868
ENSG00000244355ENST00000375825A0A1L6Z9X4

Expression (GTEx)

0
1
2
3
4
5
6
7
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Post-translational modification: synthesis of GPI-anchored proteinsREACTOMER-HSA-163125

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
194235402009Common variation in genes related to innate immunity and risk of adult glioma.19
204069642010Risk of meningioma and common variation in genes related to innate immunity.12
204387852010Polymorphisms in innate immunity genes and risk of childhood leukemia.5
306700492019JAK/Stat5-mediated subtype-specific lymphocyte antigen 6 complex, locus G6D (LY6G6D) expression drives mismatch repair proficient colorectal cancer.1
198070192009[Detection of LY6G6D gene exon-intron structure,].0

Citation

Dessen P

LY6G6D (lymphocyte antigen 6 family member G6D)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57964/ly6g6d