Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

LY6H (lymphocyte antigen 6 family member H)

Identity

Alias_symbol (synonym)NMLY6
Other alias
HGNC (Hugo) LY6H
LocusID (NCBI) 4062
Atlas_Id 54437
Location 8q24.3  [Link to chromosome band 8q24]
Location_base_pair Starts at 143157914 and ends at 143160636 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PVT1 (8q24.21) / LY6H (8q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Small Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)LY6H   6728
Cards
Entrez_Gene (NCBI)LY6H  4062  lymphocyte antigen 6 family member H
AliasesNMLY6
GeneCards (Weizmann)LY6H
Ensembl hg19 (Hinxton)ENSG00000176956 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000176956 [Gene_View]  chr8:143157914-143160636 [Contig_View]  LY6H [Vega]
ICGC DataPortalENSG00000176956
TCGA cBioPortalLY6H
AceView (NCBI)LY6H
Genatlas (Paris)LY6H
WikiGenes4062
SOURCE (Princeton)LY6H
Genetics Home Reference (NIH)LY6H
Genomic and cartography
GoldenPath hg38 (UCSC)LY6H  -     chr8:143157914-143160636 -  8q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LY6H  -     8q24.3   [Description]    (hg19-Feb_2009)
EnsemblLY6H - 8q24.3 [CytoView hg19]  LY6H - 8q24.3 [CytoView hg38]
Mapping of homologs : NCBILY6H [Mapview hg19]  LY6H [Mapview hg38]
OMIM603625   
Gene and transcription
Genbank (Entrez)AB012293 AK314139 BC028894 BC030192 BC053355
RefSeq transcript (Entrez)NM_001130478 NM_001135655 NM_002347
RefSeq genomic (Entrez)NC_000008 NC_018919 NT_187573
Consensus coding sequences : CCDS (NCBI)LY6H
Cluster EST : UnigeneHs.159590 [ NCBI ]
CGAP (NCI)Hs.159590
Alternative Splicing GalleryENSG00000176956
Gene ExpressionLY6H [ NCBI-GEO ]   LY6H [ EBI - ARRAY_EXPRESS ]   LY6H [ SEEK ]   LY6H [ MEM ]
Gene Expression Viewer (FireBrowse)LY6H [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4062
GTEX Portal (Tissue expression)LY6H
Human Protein AtlasENSG00000176956-LY6H [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO94772   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO94772  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO94772
Splice isoforms : SwissVarO94772
PhosPhoSitePlusO94772
Domains : Interpro (EBI)LY6_UPA_recep-like   
Domain families : Pfam (Sanger)UPAR_LY6 (PF00021)   
Domain families : Pfam (NCBI)pfam00021   
Domain families : Smart (EMBL)LU (SM00134)  
Conserved Domain (NCBI)LY6H
DMDM Disease mutations4062
Blocks (Seattle)LY6H
SuperfamilyO94772
Human Protein Atlas [tissue]ENSG00000176956-LY6H [tissue]
Peptide AtlasO94772
HPRD04691
IPIIPI00913871   IPI00014964   
Protein Interaction databases
DIP (DOE-UCLA)O94772
IntAct (EBI)O94772
FunCoupENSG00000176956
BioGRIDLY6H
STRING (EMBL)LY6H
ZODIACLY6H
Ontologies - Pathways
QuickGOO94772
Ontology : AmiGOprotein binding  extracellular region  plasma membrane  C-terminal protein lipidation  nervous system development  animal organ morphogenesis  anchored component of membrane  
Ontology : EGO-EBIprotein binding  extracellular region  plasma membrane  C-terminal protein lipidation  nervous system development  animal organ morphogenesis  anchored component of membrane  
NDEx NetworkLY6H
Atlas of Cancer Signalling NetworkLY6H
Wikipedia pathwaysLY6H
Orthology - Evolution
OrthoDB4062
GeneTree (enSembl)ENSG00000176956
Phylogenetic Trees/Animal Genes : TreeFamLY6H
HOVERGENO94772
HOGENOMO94772
Homologs : HomoloGeneLY6H
Homology/Alignments : Family Browser (UCSC)LY6H
Gene fusions - Rearrangements
Fusion : MitelmanPVT1/LY6H [8q24.21/8q24.3]  [t(8;8)(q24;q24)]  
Tumor Fusion PortalLY6H
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLY6H [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LY6H
dbVarLY6H
ClinVarLY6H
1000_GenomesLY6H 
Exome Variant ServerLY6H
ExAC (Exome Aggregation Consortium)ENSG00000176956
GNOMAD BrowserENSG00000176956
Genetic variants : HAPMAP4062
Genomic Variants (DGV)LY6H [DGVbeta]
DECIPHERLY6H [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLY6H 
Mutations
ICGC Data PortalLY6H 
TCGA Data PortalLY6H 
Broad Tumor PortalLY6H
OASIS PortalLY6H [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLY6H  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLY6H
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LY6H
DgiDB (Drug Gene Interaction Database)LY6H
DoCM (Curated mutations)LY6H (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LY6H (select a term)
intoGenLY6H
Cancer3DLY6H(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603625   
Orphanet
DisGeNETLY6H
MedgenLY6H
Genetic Testing Registry LY6H
NextProtO94772 [Medical]
TSGene4062
GENETestsLY6H
Target ValidationLY6H
Huge Navigator LY6H [HugePedia]
snp3D : Map Gene to Disease4062
BioCentury BCIQLY6H
ClinGenLY6H
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4062
Chemical/Pharm GKB GenePA30492
Clinical trialLY6H
Miscellaneous
canSAR (ICR)LY6H (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLY6H
EVEXLY6H
GoPubMedLY6H
iHOPLY6H
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:21:09 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.