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LY96 (lymphocyte antigen 96)

Identity

Alias_symbol (synonym)MD-2
Other aliasESOP-1
MD2
ly-96
HGNC (Hugo) LY96
LocusID (NCBI) 23643
Atlas_Id 52505
Location 8q21.11  [Link to chromosome band 8q21]
Location_base_pair Starts at 74903564 and ends at 74941307 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LY96   17156
Cards
Entrez_Gene (NCBI)LY96  23643  lymphocyte antigen 96
AliasesESOP-1; MD-2; MD2; ly-96
GeneCards (Weizmann)LY96
Ensembl hg19 (Hinxton)ENSG00000154589 [Gene_View]  chr8:74903564-74941307 [Contig_View]  LY96 [Vega]
Ensembl hg38 (Hinxton)ENSG00000154589 [Gene_View]  chr8:74903564-74941307 [Contig_View]  LY96 [Vega]
ICGC DataPortalENSG00000154589
TCGA cBioPortalLY96
AceView (NCBI)LY96
Genatlas (Paris)LY96
WikiGenes23643
SOURCE (Princeton)LY96
Genetics Home Reference (NIH)LY96
Genomic and cartography
GoldenPath hg19 (UCSC)LY96  -     chr8:74903564-74941307 +  8q21.11   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)LY96  -     8q21.11   [Description]    (hg38-Dec_2013)
EnsemblLY96 - 8q21.11 [CytoView hg19]  LY96 - 8q21.11 [CytoView hg38]
Mapping of homologs : NCBILY96 [Mapview hg19]  LY96 [Mapview hg38]
OMIM605243   
Gene and transcription
Genbank (Entrez)AB018549 AB446498 AF168121 BC020690 BG435728
RefSeq transcript (Entrez)NM_001195797 NM_015364
RefSeq genomic (Entrez)NC_000008 NC_018919 NT_008183 NW_004929339
Consensus coding sequences : CCDS (NCBI)LY96
Cluster EST : UnigeneHs.726603 [ NCBI ]
CGAP (NCI)Hs.726603
Alternative Splicing GalleryENSG00000154589
Gene ExpressionLY96 [ NCBI-GEO ]   LY96 [ EBI - ARRAY_EXPRESS ]   LY96 [ SEEK ]   LY96 [ MEM ]
Gene Expression Viewer (FireBrowse)LY96 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23643
GTEX Portal (Tissue expression)LY96
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6Y9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6Y9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6Y9
Splice isoforms : SwissVarQ9Y6Y9
PhosPhoSitePlusQ9Y6Y9
Domains : Interpro (EBI)Ig_E-set    ML_dom   
Domain families : Pfam (Sanger)E1_DerP2_DerF2 (PF02221)   
Domain families : Pfam (NCBI)pfam02221   
Domain families : Smart (EMBL)ML (SM00737)  
Conserved Domain (NCBI)LY96
DMDM Disease mutations23643
Blocks (Seattle)LY96
PDB (SRS)1T2Z    2E56    2E59    2Z65    3FXI    3ULA    4G8A   
PDB (PDBSum)1T2Z    2E56    2E59    2Z65    3FXI    3ULA    4G8A   
PDB (IMB)1T2Z    2E56    2E59    2Z65    3FXI    3ULA    4G8A   
PDB (RSDB)1T2Z    2E56    2E59    2Z65    3FXI    3ULA    4G8A   
Structural Biology KnowledgeBase1T2Z    2E56    2E59    2Z65    3FXI    3ULA    4G8A   
SCOP (Structural Classification of Proteins)1T2Z    2E56    2E59    2Z65    3FXI    3ULA    4G8A   
CATH (Classification of proteins structures)1T2Z    2E56    2E59    2Z65    3FXI    3ULA    4G8A   
SuperfamilyQ9Y6Y9
Human Protein AtlasENSG00000154589
Peptide AtlasQ9Y6Y9
HPRD05579
IPIIPI00022250   IPI00974245   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6Y9
IntAct (EBI)Q9Y6Y9
FunCoupENSG00000154589
BioGRIDLY96
STRING (EMBL)LY96
ZODIACLY96
Ontologies - Pathways
QuickGOQ9Y6Y9
Ontology : AmiGOlipopolysaccharide receptor activity  MyD88-dependent toll-like receptor signaling pathway  MyD88-independent toll-like receptor signaling pathway  protein binding  extracellular space  plasma membrane  inflammatory response  cellular defense response  cell surface receptor signaling pathway  I-kappaB kinase/NF-kappaB signaling  endosome membrane  coreceptor activity  intrinsic component of plasma membrane  lipopolysaccharide-mediated signaling pathway  positive regulation of lipopolysaccharide-mediated signaling pathway  response to lipopolysaccharide  detection of lipopolysaccharide  positive regulation of tumor necrosis factor production  negative regulation of MyD88-independent toll-like receptor signaling pathway  toll-like receptor 4 signaling pathway  toll-like receptor 4 signaling pathway  TRIF-dependent toll-like receptor signaling pathway  innate immune response  lipopolysaccharide receptor complex  necroptotic process  apoptotic signaling pathway  
Ontology : EGO-EBIlipopolysaccharide receptor activity  MyD88-dependent toll-like receptor signaling pathway  MyD88-independent toll-like receptor signaling pathway  protein binding  extracellular space  plasma membrane  inflammatory response  cellular defense response  cell surface receptor signaling pathway  I-kappaB kinase/NF-kappaB signaling  endosome membrane  coreceptor activity  intrinsic component of plasma membrane  lipopolysaccharide-mediated signaling pathway  positive regulation of lipopolysaccharide-mediated signaling pathway  response to lipopolysaccharide  detection of lipopolysaccharide  positive regulation of tumor necrosis factor production  negative regulation of MyD88-independent toll-like receptor signaling pathway  toll-like receptor 4 signaling pathway  toll-like receptor 4 signaling pathway  TRIF-dependent toll-like receptor signaling pathway  innate immune response  lipopolysaccharide receptor complex  necroptotic process  apoptotic signaling pathway  
Pathways : KEGGNF-kappa B signaling pathway    Toll-like receptor signaling pathway    Pathogenic Escherichia coli infection    Pertussis    Toxoplasmosis   
NDEx NetworkLY96
Atlas of Cancer Signalling NetworkLY96
Wikipedia pathwaysLY96
Orthology - Evolution
OrthoDB23643
GeneTree (enSembl)ENSG00000154589
Phylogenetic Trees/Animal Genes : TreeFamLY96
HOVERGENQ9Y6Y9
HOGENOMQ9Y6Y9
Homologs : HomoloGeneLY96
Homology/Alignments : Family Browser (UCSC)LY96
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLY96 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LY96
dbVarLY96
ClinVarLY96
1000_GenomesLY96 
Exome Variant ServerLY96
ExAC (Exome Aggregation Consortium)LY96 (select the gene name)
Genetic variants : HAPMAP23643
Genomic Variants (DGV)LY96 [DGVbeta]
DECIPHER (Syndromes)8:74903564-74941307  ENSG00000154589
CONAN: Copy Number AnalysisLY96 
Mutations
ICGC Data PortalLY96 
TCGA Data PortalLY96 
Broad Tumor PortalLY96
OASIS PortalLY96 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLY96  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLY96
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Pharmacogenomics of Infectious Diseases (PGx_IfD )
BioMutasearch LY96
DgiDB (Drug Gene Interaction Database)LY96
DoCM (Curated mutations)LY96 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LY96 (select a term)
intoGenLY96
Cancer3DLY96(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605243   
Orphanet
MedgenLY96
Genetic Testing Registry LY96
NextProtQ9Y6Y9 [Medical]
TSGene23643
GENETestsLY96
Huge Navigator LY96 [HugePedia]
snp3D : Map Gene to Disease23643
BioCentury BCIQLY96
ClinGenLY96
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23643
Chemical/Pharm GKB GenePA134924906
Clinical trialLY96
Miscellaneous
canSAR (ICR)LY96 (select the gene name)
Probes
Litterature
PubMed120 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLY96
EVEXLY96
GoPubMedLY96
iHOPLY96
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:14:01 CET 2017

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