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LYNX1 (Ly6/neurotoxin 1)

Identity

Alias_symbol (synonym)SLURP2
Other alias
HGNC (Hugo) LYNX1
LocusID (NCBI) 66004
Atlas_Id 43968
Location 8q24.3  [Link to chromosome band 8q24]
Location_base_pair Starts at 142764334 and ends at 142777848 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LYNX1   29604
Cards
Entrez_Gene (NCBI)LYNX1  66004  Ly6/neurotoxin 1
AliasesSLURP2
GeneCards (Weizmann)LYNX1
Ensembl hg19 (Hinxton)ENSG00000180155 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000180155 [Gene_View]  chr8:142764334-142777848 [Contig_View]  LYNX1 [Vega]
ICGC DataPortalENSG00000180155
TCGA cBioPortalLYNX1
AceView (NCBI)LYNX1
Genatlas (Paris)LYNX1
WikiGenes66004
SOURCE (Princeton)LYNX1
Genetics Home Reference (NIH)LYNX1
Genomic and cartography
GoldenPath hg38 (UCSC)LYNX1  -     chr8:142764334-142777848 -  8q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LYNX1  -     8q24.3   [Description]    (hg19-Feb_2009)
EnsemblLYNX1 - 8q24.3 [CytoView hg19]  LYNX1 - 8q24.3 [CytoView hg38]
Mapping of homologs : NCBILYNX1 [Mapview hg19]  LYNX1 [Mapview hg38]
OMIM606110   
Gene and transcription
Genbank (Entrez)AB081838 AF321824 AI494395 AK123335 AK126845
RefSeq transcript (Entrez)NM_023946 NM_177457 NM_177458 NM_177476 NM_177477
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LYNX1
Cluster EST : UnigeneHs.604828 [ NCBI ]
CGAP (NCI)Hs.604828
Alternative Splicing GalleryENSG00000180155
Gene ExpressionLYNX1 [ NCBI-GEO ]   LYNX1 [ EBI - ARRAY_EXPRESS ]   LYNX1 [ SEEK ]   LYNX1 [ MEM ]
Gene Expression Viewer (FireBrowse)LYNX1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)66004
GTEX Portal (Tissue expression)LYNX1
Human Protein AtlasENSG00000180155-LYNX1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BZG9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BZG9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BZG9
Splice isoforms : SwissVarQ9BZG9
PhosPhoSitePlusQ9BZG9
Domains : Interpro (EBI)LY6_UPA_recep-like   
Domain families : Pfam (Sanger)UPAR_LY6 (PF00021)   
Domain families : Pfam (NCBI)pfam00021   
Conserved Domain (NCBI)LYNX1
DMDM Disease mutations66004
Blocks (Seattle)LYNX1
PDB (SRS)1VYE    2L03    2N99   
PDB (PDBSum)1VYE    2L03    2N99   
PDB (IMB)1VYE    2L03    2N99   
PDB (RSDB)1VYE    2L03    2N99   
Structural Biology KnowledgeBase1VYE    2L03    2N99   
SCOP (Structural Classification of Proteins)1VYE    2L03    2N99   
CATH (Classification of proteins structures)1VYE    2L03    2N99   
SuperfamilyQ9BZG9
Human Protein Atlas [tissue]ENSG00000180155-LYNX1 [tissue]
Peptide AtlasQ9BZG9
HPRD16201
IPIIPI00219827   IPI00289058   IPI00982455   IPI00218851   IPI00980650   IPI00984181   IPI00794450   IPI00981301   
Protein Interaction databases
DIP (DOE-UCLA)Q9BZG9
IntAct (EBI)Q9BZG9
FunCoupENSG00000180155
BioGRIDLYNX1
STRING (EMBL)LYNX1
ZODIACLYNX1
Ontologies - Pathways
QuickGOQ9BZG9
Ontology : AmiGOplasma membrane  synaptic transmission, cholinergic  ion channel inhibitor activity  dendrite  acetylcholine receptor inhibitor activity  anchored component of membrane  extracellular exosome  negative regulation of receptor activity  
Ontology : EGO-EBIplasma membrane  synaptic transmission, cholinergic  ion channel inhibitor activity  dendrite  acetylcholine receptor inhibitor activity  anchored component of membrane  extracellular exosome  negative regulation of receptor activity  
NDEx NetworkLYNX1
Atlas of Cancer Signalling NetworkLYNX1
Wikipedia pathwaysLYNX1
Orthology - Evolution
OrthoDB66004
GeneTree (enSembl)ENSG00000180155
Phylogenetic Trees/Animal Genes : TreeFamLYNX1
HOVERGENQ9BZG9
HOGENOMQ9BZG9
Homologs : HomoloGeneLYNX1
Homology/Alignments : Family Browser (UCSC)LYNX1
Gene fusions - Rearrangements
Tumor Fusion PortalLYNX1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLYNX1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LYNX1
dbVarLYNX1
ClinVarLYNX1
1000_GenomesLYNX1 
Exome Variant ServerLYNX1
ExAC (Exome Aggregation Consortium)ENSG00000180155
GNOMAD BrowserENSG00000180155
Genetic variants : HAPMAP66004
Genomic Variants (DGV)LYNX1 [DGVbeta]
DECIPHERLYNX1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLYNX1 
Mutations
ICGC Data PortalLYNX1 
TCGA Data PortalLYNX1 
Broad Tumor PortalLYNX1
OASIS PortalLYNX1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLYNX1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLYNX1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LYNX1
DgiDB (Drug Gene Interaction Database)LYNX1
DoCM (Curated mutations)LYNX1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LYNX1 (select a term)
intoGenLYNX1
Cancer3DLYNX1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606110   
Orphanet
DisGeNETLYNX1
MedgenLYNX1
Genetic Testing Registry LYNX1
NextProtQ9BZG9 [Medical]
TSGene66004
GENETestsLYNX1
Target ValidationLYNX1
Huge Navigator LYNX1 [HugePedia]
snp3D : Map Gene to Disease66004
BioCentury BCIQLYNX1
ClinGenLYNX1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD66004
Chemical/Pharm GKB GenePA134874147
Clinical trialLYNX1
Miscellaneous
canSAR (ICR)LYNX1 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLYNX1
EVEXLYNX1
GoPubMedLYNX1
iHOPLYNX1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:21:10 CET 2017

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