Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

LYPD6 (LY6/PLAUR domain containing 6)

Identity

Alias_symbol (synonym)MGC52057
Other alias-
HGNC (Hugo) LYPD6
LocusID (NCBI) 130574
Atlas_Id 68720
Location 2q23.2  [Link to chromosome band 2q23]
Location_base_pair Starts at 149329985 and ends at 149474145 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
RIF1 (2q23.3) / LYPD6 (2q23.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LYPD6   28751
Cards
Entrez_Gene (NCBI)LYPD6  130574  LY6/PLAUR domain containing 6
Aliases
GeneCards (Weizmann)LYPD6
Ensembl hg19 (Hinxton)ENSG00000187123 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000187123 [Gene_View]  chr2:149329985-149474145 [Contig_View]  LYPD6 [Vega]
ICGC DataPortalENSG00000187123
TCGA cBioPortalLYPD6
AceView (NCBI)LYPD6
Genatlas (Paris)LYPD6
WikiGenes130574
SOURCE (Princeton)LYPD6
Genetics Home Reference (NIH)LYPD6
Genomic and cartography
GoldenPath hg38 (UCSC)LYPD6  -     chr2:149329985-149474145 +  2q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LYPD6  -     2q23.2   [Description]    (hg19-Feb_2009)
EnsemblLYPD6 - 2q23.2 [CytoView hg19]  LYPD6 - 2q23.2 [CytoView hg38]
Mapping of homologs : NCBILYPD6 [Mapview hg19]  LYPD6 [Mapview hg38]
OMIM613359   
Gene and transcription
Genbank (Entrez)AK055699 AK124733 AK309248 AL831852 AY358623
RefSeq transcript (Entrez)NM_001195685 NM_194317
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LYPD6
Cluster EST : UnigeneHs.21929 [ NCBI ]
CGAP (NCI)Hs.21929
Alternative Splicing GalleryENSG00000187123
Gene ExpressionLYPD6 [ NCBI-GEO ]   LYPD6 [ EBI - ARRAY_EXPRESS ]   LYPD6 [ SEEK ]   LYPD6 [ MEM ]
Gene Expression Viewer (FireBrowse)LYPD6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)130574
GTEX Portal (Tissue expression)LYPD6
Human Protein AtlasENSG00000187123-LYPD6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86Y78   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86Y78  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86Y78
Splice isoforms : SwissVarQ86Y78
PhosPhoSitePlusQ86Y78
Domains : Interpro (EBI)LYPD6   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)LYPD6
DMDM Disease mutations130574
Blocks (Seattle)LYPD6
SuperfamilyQ86Y78
Human Protein Atlas [tissue]ENSG00000187123-LYPD6 [tissue]
Peptide AtlasQ86Y78
HPRD14676
IPIIPI00046763   IPI00917917   IPI00916900   
Protein Interaction databases
DIP (DOE-UCLA)Q86Y78
IntAct (EBI)Q86Y78
FunCoupENSG00000187123
BioGRIDLYPD6
STRING (EMBL)LYPD6
ZODIACLYPD6
Ontologies - Pathways
QuickGOQ86Y78
Ontology : AmiGOprotein binding  extracellular region  cytoplasm  plasma membrane  cell junction  acetylcholine receptor inhibitor activity  anchored component of membrane  neuron projection  membrane raft  synapse  regulation of neurotransmitter receptor activity  negative regulation of receptor activity  
Ontology : EGO-EBIprotein binding  extracellular region  cytoplasm  plasma membrane  cell junction  acetylcholine receptor inhibitor activity  anchored component of membrane  neuron projection  membrane raft  synapse  regulation of neurotransmitter receptor activity  negative regulation of receptor activity  
NDEx NetworkLYPD6
Atlas of Cancer Signalling NetworkLYPD6
Wikipedia pathwaysLYPD6
Orthology - Evolution
OrthoDB130574
GeneTree (enSembl)ENSG00000187123
Phylogenetic Trees/Animal Genes : TreeFamLYPD6
HOVERGENQ86Y78
HOGENOMQ86Y78
Homologs : HomoloGeneLYPD6
Homology/Alignments : Family Browser (UCSC)LYPD6
Gene fusions - Rearrangements
Tumor Fusion PortalLYPD6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLYPD6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LYPD6
dbVarLYPD6
ClinVarLYPD6
1000_GenomesLYPD6 
Exome Variant ServerLYPD6
ExAC (Exome Aggregation Consortium)ENSG00000187123
GNOMAD BrowserENSG00000187123
Genetic variants : HAPMAP130574
Genomic Variants (DGV)LYPD6 [DGVbeta]
DECIPHERLYPD6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLYPD6 
Mutations
ICGC Data PortalLYPD6 
TCGA Data PortalLYPD6 
Broad Tumor PortalLYPD6
OASIS PortalLYPD6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLYPD6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLYPD6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LYPD6
DgiDB (Drug Gene Interaction Database)LYPD6
DoCM (Curated mutations)LYPD6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LYPD6 (select a term)
intoGenLYPD6
Cancer3DLYPD6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613359   
Orphanet
DisGeNETLYPD6
MedgenLYPD6
Genetic Testing Registry LYPD6
NextProtQ86Y78 [Medical]
TSGene130574
GENETestsLYPD6
Target ValidationLYPD6
Huge Navigator LYPD6 [HugePedia]
snp3D : Map Gene to Disease130574
BioCentury BCIQLYPD6
ClinGenLYPD6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD130574
Chemical/Pharm GKB GenePA147357619
Clinical trialLYPD6
Miscellaneous
canSAR (ICR)LYPD6 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLYPD6
EVEXLYPD6
GoPubMedLYPD6
iHOPLYPD6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Nov 20 19:55:38 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.