Atlas of Genetics and Cytogenetics in Oncology and Haematology

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LYPLAL1 (lysophospholipase like 1)

Identity

Alias (NCBI)Q96AV0
HGNC (Hugo) LYPLAL1
HGNC Alias symbQ96AV0
HGNC Previous namelysophospholipase-like 1
LocusID (NCBI) 127018
Atlas_Id 68724
Location 1q41  [Link to chromosome band 1q41]
Location_base_pair Starts at 219173831 and ends at 219212865 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SLC25A25 (9q34.11) / LYPLAL1 (1q41)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)LYPLAL1   20440
Cards
Entrez_Gene (NCBI)LYPLAL1    lysophospholipase like 1
AliasesQ96AV0
GeneCards (Weizmann)LYPLAL1
Ensembl hg19 (Hinxton)ENSG00000143353 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000143353 [Gene_View]  ENSG00000143353 [Sequence]  chr1:219173831-219212865 [Contig_View]  LYPLAL1 [Vega]
ICGC DataPortalENSG00000143353
TCGA cBioPortalLYPLAL1
AceView (NCBI)LYPLAL1
Genatlas (Paris)LYPLAL1
SOURCE (Princeton)LYPLAL1
Genetics Home Reference (NIH)LYPLAL1
Genomic and cartography
GoldenPath hg38 (UCSC)LYPLAL1  -     chr1:219173831-219212865 +  1q41   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LYPLAL1  -     1q41   [Description]    (hg19-Feb_2009)
GoldenPathLYPLAL1 - 1q41 [CytoView hg19]  LYPLAL1 - 1q41 [CytoView hg38]
ImmunoBaseENSG00000143353
genome Data Viewer NCBILYPLAL1 [Mapview hg19]  
OMIM616548   
Gene and transcription
Genbank (Entrez)AA417842 AA424278 AK123628 AK129913 AK291542
RefSeq transcript (Entrez)NM_001300769 NM_001300770 NM_001300771 NM_001300772 NM_001350628 NM_001350629 NM_138794
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LYPLAL1
Alternative Splicing GalleryENSG00000143353
Gene ExpressionLYPLAL1 [ NCBI-GEO ]   LYPLAL1 [ EBI - ARRAY_EXPRESS ]   LYPLAL1 [ SEEK ]   LYPLAL1 [ MEM ]
Gene Expression Viewer (FireBrowse)LYPLAL1 [ Firebrowse - Broad ]
GenevisibleExpression of LYPLAL1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)127018
GTEX Portal (Tissue expression)LYPLAL1
Human Protein AtlasENSG00000143353-LYPLAL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5VWZ2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5VWZ2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5VWZ2
Splice isoforms : SwissVarQ5VWZ2
PhosPhoSitePlusQ5VWZ2
Domains : Interpro (EBI)AB_hydrolase    PLipase/COase/thioEstase   
Domain families : Pfam (Sanger)Abhydrolase_2 (PF02230)   
Domain families : Pfam (NCBI)pfam02230   
Conserved Domain (NCBI)LYPLAL1
Blocks (Seattle)LYPLAL1
PDB (RSDB)3U0V    5KRE   
PDB Europe3U0V    5KRE   
PDB (PDBSum)3U0V    5KRE   
PDB (IMB)3U0V    5KRE   
Structural Biology KnowledgeBase3U0V    5KRE   
SCOP (Structural Classification of Proteins)3U0V    5KRE   
CATH (Classification of proteins structures)3U0V    5KRE   
SuperfamilyQ5VWZ2
Human Protein Atlas [tissue]ENSG00000143353-LYPLAL1 [tissue]
Peptide AtlasQ5VWZ2
HPRD14335
IPIIPI00059762   IPI00642838   
Protein Interaction databases
DIP (DOE-UCLA)Q5VWZ2
IntAct (EBI)Q5VWZ2
BioGRIDLYPLAL1
STRING (EMBL)LYPLAL1
ZODIACLYPLAL1
Ontologies - Pathways
QuickGOQ5VWZ2
Ontology : AmiGOprotein depalmitoylation  lysophospholipase activity  cytoplasm  cytosol  biological_process  palmitoyl-(protein) hydrolase activity  carboxylic ester hydrolase activity  
Ontology : EGO-EBIprotein depalmitoylation  lysophospholipase activity  cytoplasm  cytosol  biological_process  palmitoyl-(protein) hydrolase activity  carboxylic ester hydrolase activity  
NDEx NetworkLYPLAL1
Atlas of Cancer Signalling NetworkLYPLAL1
Wikipedia pathwaysLYPLAL1
Orthology - Evolution
OrthoDB127018
GeneTree (enSembl)ENSG00000143353
Phylogenetic Trees/Animal Genes : TreeFamLYPLAL1
HOGENOMQ5VWZ2
Homologs : HomoloGeneLYPLAL1
Homology/Alignments : Family Browser (UCSC)LYPLAL1
Gene fusions - Rearrangements
Fusion : QuiverLYPLAL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLYPLAL1 [hg38]
dbVarLYPLAL1
ClinVarLYPLAL1
MonarchLYPLAL1
1000_GenomesLYPLAL1 
Exome Variant ServerLYPLAL1
GNOMAD BrowserENSG00000143353
Varsome BrowserLYPLAL1
Genomic Variants (DGV)LYPLAL1 [DGVbeta]
DECIPHERLYPLAL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLYPLAL1 
Mutations
ICGC Data PortalLYPLAL1 
TCGA Data PortalLYPLAL1 
Broad Tumor PortalLYPLAL1
OASIS PortalLYPLAL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLYPLAL1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DLYPLAL1
Mutations and Diseases : HGMDLYPLAL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LYPLAL1
DgiDB (Drug Gene Interaction Database)LYPLAL1
DoCM (Curated mutations)LYPLAL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LYPLAL1 (select a term)
intoGenLYPLAL1
Cancer3DLYPLAL1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616548   
Orphanet
DisGeNETLYPLAL1
MedgenLYPLAL1
Genetic Testing Registry LYPLAL1
NextProtQ5VWZ2 [Medical]
GENETestsLYPLAL1
Target ValidationLYPLAL1
Huge Navigator LYPLAL1 [HugePedia]
ClinGenLYPLAL1
Clinical trials, drugs, therapy
MyCancerGenomeLYPLAL1
Protein Interactions : CTD
Pharm GKB GenePA134986975
Clinical trialLYPLAL1
Miscellaneous
canSAR (ICR)LYPLAL1 (select the gene name)
HarmonizomeLYPLAL1
DataMed IndexLYPLAL1
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLYPLAL1
EVEXLYPLAL1
GoPubMedLYPLAL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Dec 5 17:12:30 CET 2020
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