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LYPLAL1 (lysophospholipase like 1)

Identity

Alias_nameslysophospholipase-like 1
Alias_symbol (synonym)Q96AV0
Other alias
HGNC (Hugo) LYPLAL1
LocusID (NCBI) 127018
Atlas_Id 68724
Location 1q41  [Link to chromosome band 1q41]
Location_base_pair Starts at 219173831 and ends at 219212865 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SLC25A25 (9q34.11) / LYPLAL1 (1q41)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LYPLAL1   20440
Cards
Entrez_Gene (NCBI)LYPLAL1  127018  lysophospholipase like 1
AliasesQ96AV0
GeneCards (Weizmann)LYPLAL1
Ensembl hg19 (Hinxton)ENSG00000143353 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000143353 [Gene_View]  chr1:219173831-219212865 [Contig_View]  LYPLAL1 [Vega]
ICGC DataPortalENSG00000143353
TCGA cBioPortalLYPLAL1
AceView (NCBI)LYPLAL1
Genatlas (Paris)LYPLAL1
WikiGenes127018
SOURCE (Princeton)LYPLAL1
Genetics Home Reference (NIH)LYPLAL1
Genomic and cartography
GoldenPath hg38 (UCSC)LYPLAL1  -     chr1:219173831-219212865 +  1q41   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LYPLAL1  -     1q41   [Description]    (hg19-Feb_2009)
EnsemblLYPLAL1 - 1q41 [CytoView hg19]  LYPLAL1 - 1q41 [CytoView hg38]
Mapping of homologs : NCBILYPLAL1 [Mapview hg19]  LYPLAL1 [Mapview hg38]
OMIM616548   
Gene and transcription
Genbank (Entrez)AA417842 AA424278 AK123628 AK129913 AK291542
RefSeq transcript (Entrez)NM_001300769 NM_001300770 NM_001300771 NM_001300772 NM_001350628 NM_001350629 NM_138794
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LYPLAL1
Cluster EST : UnigeneHs.657617 [ NCBI ]
CGAP (NCI)Hs.657617
Alternative Splicing GalleryENSG00000143353
Gene ExpressionLYPLAL1 [ NCBI-GEO ]   LYPLAL1 [ EBI - ARRAY_EXPRESS ]   LYPLAL1 [ SEEK ]   LYPLAL1 [ MEM ]
Gene Expression Viewer (FireBrowse)LYPLAL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)127018
GTEX Portal (Tissue expression)LYPLAL1
Human Protein AtlasENSG00000143353-LYPLAL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5VWZ2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5VWZ2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5VWZ2
Splice isoforms : SwissVarQ5VWZ2
PhosPhoSitePlusQ5VWZ2
Domains : Interpro (EBI)AB_hydrolase    PLipase/COase/thioEstase   
Domain families : Pfam (Sanger)Abhydrolase_2 (PF02230)   
Domain families : Pfam (NCBI)pfam02230   
Conserved Domain (NCBI)LYPLAL1
DMDM Disease mutations127018
Blocks (Seattle)LYPLAL1
PDB (SRS)3U0V    5KRE   
PDB (PDBSum)3U0V    5KRE   
PDB (IMB)3U0V    5KRE   
PDB (RSDB)3U0V    5KRE   
Structural Biology KnowledgeBase3U0V    5KRE   
SCOP (Structural Classification of Proteins)3U0V    5KRE   
CATH (Classification of proteins structures)3U0V    5KRE   
SuperfamilyQ5VWZ2
Human Protein Atlas [tissue]ENSG00000143353-LYPLAL1 [tissue]
Peptide AtlasQ5VWZ2
HPRD14335
IPIIPI00059762   IPI00642838   
Protein Interaction databases
DIP (DOE-UCLA)Q5VWZ2
IntAct (EBI)Q5VWZ2
FunCoupENSG00000143353
BioGRIDLYPLAL1
STRING (EMBL)LYPLAL1
ZODIACLYPLAL1
Ontologies - Pathways
QuickGOQ5VWZ2
Ontology : AmiGOprotein depalmitoylation  lysophospholipase activity  cytoplasm  cytosol  biological_process  palmitoyl-(protein) hydrolase activity  carboxylic ester hydrolase activity  extracellular exosome  
Ontology : EGO-EBIprotein depalmitoylation  lysophospholipase activity  cytoplasm  cytosol  biological_process  palmitoyl-(protein) hydrolase activity  carboxylic ester hydrolase activity  extracellular exosome  
NDEx NetworkLYPLAL1
Atlas of Cancer Signalling NetworkLYPLAL1
Wikipedia pathwaysLYPLAL1
Orthology - Evolution
OrthoDB127018
GeneTree (enSembl)ENSG00000143353
Phylogenetic Trees/Animal Genes : TreeFamLYPLAL1
HOVERGENQ5VWZ2
HOGENOMQ5VWZ2
Homologs : HomoloGeneLYPLAL1
Homology/Alignments : Family Browser (UCSC)LYPLAL1
Gene fusions - Rearrangements
Tumor Fusion PortalLYPLAL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLYPLAL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LYPLAL1
dbVarLYPLAL1
ClinVarLYPLAL1
1000_GenomesLYPLAL1 
Exome Variant ServerLYPLAL1
ExAC (Exome Aggregation Consortium)ENSG00000143353
GNOMAD BrowserENSG00000143353
Genetic variants : HAPMAP127018
Genomic Variants (DGV)LYPLAL1 [DGVbeta]
DECIPHERLYPLAL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLYPLAL1 
Mutations
ICGC Data PortalLYPLAL1 
TCGA Data PortalLYPLAL1 
Broad Tumor PortalLYPLAL1
OASIS PortalLYPLAL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLYPLAL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLYPLAL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LYPLAL1
DgiDB (Drug Gene Interaction Database)LYPLAL1
DoCM (Curated mutations)LYPLAL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LYPLAL1 (select a term)
intoGenLYPLAL1
Cancer3DLYPLAL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616548   
Orphanet
DisGeNETLYPLAL1
MedgenLYPLAL1
Genetic Testing Registry LYPLAL1
NextProtQ5VWZ2 [Medical]
TSGene127018
GENETestsLYPLAL1
Target ValidationLYPLAL1
Huge Navigator LYPLAL1 [HugePedia]
snp3D : Map Gene to Disease127018
BioCentury BCIQLYPLAL1
ClinGenLYPLAL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD127018
Chemical/Pharm GKB GenePA134986975
Clinical trialLYPLAL1
Miscellaneous
canSAR (ICR)LYPLAL1 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLYPLAL1
EVEXLYPLAL1
GoPubMedLYPLAL1
iHOPLYPLAL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:01:20 CET 2017

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