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LYRM4 (LYR motif containing 4)

Identity

Alias (NCBI)C6orf149
CGI-203
COXPD19
ISD11
HGNC (Hugo) LYRM4
HGNC Alias symbCGI-203
ISD11
HGNC Previous nameC6orf149
HGNC Previous namechromosome 6 open reading frame 149
LocusID (NCBI) 57128
Atlas_Id 68728
Location 6p25.1  [Link to chromosome band 6p25]
Location_base_pair Starts at 5108419 and ends at 5260950 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
E2F6 (2p25.1) / LYRM4 (6p25.1)LYRM4 (6p25.1) / PSIP1 (9p22.3)RNF144B (6p22.3) / LYRM4 (6p25.1)
RPP40 (6p25.1) / LYRM4 (6p25.1)RREB1 (6p24.3) / LYRM4 (6p25.1)RPP40 LYRM4
E2F6 LYRM4RNF144B LYRM4RREB1 LYRM4

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)LYRM4   21365
Cards
Entrez_Gene (NCBI)LYRM4    LYR motif containing 4
AliasesC6orf149; CGI-203; COXPD19; ISD11
GeneCards (Weizmann)LYRM4
Ensembl hg19 (Hinxton)ENSG00000214113 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000214113 [Gene_View]  ENSG00000214113 [Sequence]  chr6:5108419-5260950 [Contig_View]  LYRM4 [Vega]
ICGC DataPortalENSG00000214113
TCGA cBioPortalLYRM4
AceView (NCBI)LYRM4
Genatlas (Paris)LYRM4
SOURCE (Princeton)LYRM4
Genetics Home Reference (NIH)LYRM4
Genomic and cartography
GoldenPath hg38 (UCSC)LYRM4  -     chr6:5108419-5260950 -  6p25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LYRM4  -     6p25.1   [Description]    (hg19-Feb_2009)
GoldenPathLYRM4 - 6p25.1 [CytoView hg19]  LYRM4 - 6p25.1 [CytoView hg38]
ImmunoBaseENSG00000214113
Genome Data Viewer NCBILYRM4 [Mapview hg19]  
OMIM613311   615595   
Gene and transcription
Genbank (Entrez)AA764791 AF088060 AF170070 AF258559 AF285118
RefSeq transcript (Entrez)NM_001164840 NM_001164841 NM_001318782 NM_001318783 NM_020408
Consensus coding sequences : CCDS (NCBI)LYRM4
Gene ExpressionLYRM4 [ NCBI-GEO ]   LYRM4 [ EBI - ARRAY_EXPRESS ]   LYRM4 [ SEEK ]   LYRM4 [ MEM ]
Gene Expression Viewer (FireBrowse)LYRM4 [ Firebrowse - Broad ]
GenevisibleExpression of LYRM4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57128
GTEX Portal (Tissue expression)LYRM4
Human Protein AtlasENSG00000214113-LYRM4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HD34   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HD34  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HD34
PhosPhoSitePlusQ9HD34
Domains : Interpro (EBI)Complex1_LYR   
Domain families : Pfam (Sanger)Complex1_LYR (PF05347)   
Domain families : Pfam (NCBI)pfam05347   
Conserved Domain (NCBI)LYRM4
PDB (RSDB)5USR    5WGB    5WKP    5WLW    6NZU    6ODD    6UXE    6W1D    6WI2    6WIH   
PDB Europe5USR    5WGB    5WKP    5WLW    6NZU    6ODD    6UXE    6W1D    6WI2    6WIH   
PDB (PDBSum)5USR    5WGB    5WKP    5WLW    6NZU    6ODD    6UXE    6W1D    6WI2    6WIH   
PDB (IMB)5USR    5WGB    5WKP    5WLW    6NZU    6ODD    6UXE    6W1D    6WI2    6WIH   
Structural Biology KnowledgeBase5USR    5WGB    5WKP    5WLW    6NZU    6ODD    6UXE    6W1D    6WI2    6WIH   
SCOP (Structural Classification of Proteins)5USR    5WGB    5WKP    5WLW    6NZU    6ODD    6UXE    6W1D    6WI2    6WIH   
CATH (Classification of proteins structures)5USR    5WGB    5WKP    5WLW    6NZU    6ODD    6UXE    6W1D    6WI2    6WIH   
SuperfamilyQ9HD34
AlphaFold pdb e-kbQ9HD34   
Human Protein Atlas [tissue]ENSG00000214113-LYRM4 [tissue]
HPRD12855
Protein Interaction databases
DIP (DOE-UCLA)Q9HD34
IntAct (EBI)Q9HD34
BioGRIDLYRM4
STRING (EMBL)LYRM4
ZODIACLYRM4
Ontologies - Pathways
QuickGOQ9HD34
Ontology : AmiGOprotein binding  mitochondrion  mitochondrial matrix  iron-sulfur cluster assembly  iron-sulfur cluster assembly  nuclear body  L-cysteine desulfurase complex  
Ontology : EGO-EBIprotein binding  mitochondrion  mitochondrial matrix  iron-sulfur cluster assembly  iron-sulfur cluster assembly  nuclear body  L-cysteine desulfurase complex  
NDEx NetworkLYRM4
Atlas of Cancer Signalling NetworkLYRM4
Wikipedia pathwaysLYRM4
Orthology - Evolution
OrthoDB57128
GeneTree (enSembl)ENSG00000214113
Phylogenetic Trees/Animal Genes : TreeFamLYRM4
Homologs : HomoloGeneLYRM4
Homology/Alignments : Family Browser (UCSC)LYRM4
Gene fusions - Rearrangements
Fusion : QuiverLYRM4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLYRM4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LYRM4
dbVarLYRM4
ClinVarLYRM4
MonarchLYRM4
1000_GenomesLYRM4 
Exome Variant ServerLYRM4
GNOMAD BrowserENSG00000214113
Varsome BrowserLYRM4
ACMGLYRM4 variants
VarityQ9HD34
Genomic Variants (DGV)LYRM4 [DGVbeta]
DECIPHERLYRM4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLYRM4 
Mutations
ICGC Data PortalLYRM4 
TCGA Data PortalLYRM4 
Broad Tumor PortalLYRM4
OASIS PortalLYRM4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICLYRM4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DLYRM4
Mutations and Diseases : HGMDLYRM4
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaLYRM4
DgiDB (Drug Gene Interaction Database)LYRM4
DoCM (Curated mutations)LYRM4
CIViC (Clinical Interpretations of Variants in Cancer)LYRM4
Cancer3DLYRM4
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613311    615595   
Orphanet22684   
DisGeNETLYRM4
MedgenLYRM4
Genetic Testing Registry LYRM4
NextProtQ9HD34 [Medical]
GENETestsLYRM4
Target ValidationLYRM4
Huge Navigator LYRM4 [HugePedia]
ClinGenLYRM4
Clinical trials, drugs, therapy
MyCancerGenomeLYRM4
Protein Interactions : CTDLYRM4
Pharm GKB GenePA162394762
PharosQ9HD34
Clinical trialLYRM4
Miscellaneous
canSAR (ICR)LYRM4
HarmonizomeLYRM4
DataMed IndexLYRM4
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXLYRM4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:06:38 CEST 2021

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