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LZTR1 (leucine zipper like transcription regulator 1)

Identity

Alias_namesleucine-zipper-like transcriptional regulator 1
Alias_symbol (synonym)LZTR-1
BTBD29
Other aliasNS10
SWNTS2
HGNC (Hugo) LZTR1
LocusID (NCBI) 8216
Atlas_Id 68742
Location 22q11.21  [Link to chromosome band 22q11]
Location_base_pair Starts at 20982269 and ends at 20999037 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LZTR1 (22q11.21) / LZTR1 (22q11.21)LZTR1 (22q11.21) / MIF4GD (17q25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)LZTR1   6742
LRG (Locus Reference Genomic)LRG_989
Cards
Entrez_Gene (NCBI)LZTR1  8216  leucine zipper like transcription regulator 1
AliasesBTBD29; LZTR-1; NS10; SWNTS2
GeneCards (Weizmann)LZTR1
Ensembl hg19 (Hinxton)ENSG00000099949 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000099949 [Gene_View]  chr22:20982269-20999037 [Contig_View]  LZTR1 [Vega]
ICGC DataPortalENSG00000099949
TCGA cBioPortalLZTR1
AceView (NCBI)LZTR1
Genatlas (Paris)LZTR1
WikiGenes8216
SOURCE (Princeton)LZTR1
Genetics Home Reference (NIH)LZTR1
Genomic and cartography
GoldenPath hg38 (UCSC)LZTR1  -     chr22:20982269-20999037 +  22q11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)LZTR1  -     22q11.21   [Description]    (hg19-Feb_2009)
EnsemblLZTR1 - 22q11.21 [CytoView hg19]  LZTR1 - 22q11.21 [CytoView hg38]
Mapping of homologs : NCBILZTR1 [Mapview hg19]  LZTR1 [Mapview hg38]
OMIM600574   615670   616564   
Gene and transcription
Genbank (Entrez)AK296347 AK310747 AK313502 AL833698 BC026214
RefSeq transcript (Entrez)NM_006767
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)LZTR1
Cluster EST : UnigeneHs.78788 [ NCBI ]
CGAP (NCI)Hs.78788
Alternative Splicing GalleryENSG00000099949
Gene ExpressionLZTR1 [ NCBI-GEO ]   LZTR1 [ EBI - ARRAY_EXPRESS ]   LZTR1 [ SEEK ]   LZTR1 [ MEM ]
Gene Expression Viewer (FireBrowse)LZTR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8216
GTEX Portal (Tissue expression)LZTR1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N653   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N653  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N653
Splice isoforms : SwissVarQ8N653
PhosPhoSitePlusQ8N653
Domaine pattern : Prosite (Expaxy)BTB (PS50097)   
Domains : Interpro (EBI)BTB/POZ_dom    Kelch-typ_b-propeller    Kelch_1    Kelch_2    SKP1/BTB/POZ   
Domain families : Pfam (Sanger)BTB (PF00651)    Kelch_1 (PF01344)    Kelch_2 (PF07646)   
Domain families : Pfam (NCBI)pfam00651    pfam01344    pfam07646   
Domain families : Smart (EMBL)BTB (SM00225)  Kelch (SM00612)  
Conserved Domain (NCBI)LZTR1
DMDM Disease mutations8216
Blocks (Seattle)LZTR1
SuperfamilyQ8N653
Human Protein AtlasENSG00000099949
Peptide AtlasQ8N653
HPRD08992
IPIIPI00024893   IPI01013184   IPI01009407   IPI00921208   IPI00878757   IPI00878270   IPI00879054   IPI00878593   IPI00879394   IPI00879545   
Protein Interaction databases
DIP (DOE-UCLA)Q8N653
IntAct (EBI)Q8N653
FunCoupENSG00000099949
BioGRIDLZTR1
STRING (EMBL)LZTR1
ZODIACLZTR1
Ontologies - Pathways
QuickGOQ8N653
Ontology : AmiGOtranscription factor activity, sequence-specific DNA binding  Golgi apparatus  regulation of transcription, DNA-templated  anatomical structure morphogenesis  
Ontology : EGO-EBItranscription factor activity, sequence-specific DNA binding  Golgi apparatus  regulation of transcription, DNA-templated  anatomical structure morphogenesis  
NDEx NetworkLZTR1
Atlas of Cancer Signalling NetworkLZTR1
Wikipedia pathwaysLZTR1
Orthology - Evolution
OrthoDB8216
GeneTree (enSembl)ENSG00000099949
Phylogenetic Trees/Animal Genes : TreeFamLZTR1
HOVERGENQ8N653
HOGENOMQ8N653
Homologs : HomoloGeneLZTR1
Homology/Alignments : Family Browser (UCSC)LZTR1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerLZTR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)LZTR1
dbVarLZTR1
ClinVarLZTR1
1000_GenomesLZTR1 
Exome Variant ServerLZTR1
ExAC (Exome Aggregation Consortium)LZTR1 (select the gene name)
Genetic variants : HAPMAP8216
Genomic Variants (DGV)LZTR1 [DGVbeta]
DECIPHERLZTR1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisLZTR1 
Mutations
ICGC Data PortalLZTR1 
TCGA Data PortalLZTR1 
Broad Tumor PortalLZTR1
OASIS PortalLZTR1 [ Somatic mutations - Copy number]
Cancer Gene: CensusLZTR1 
Somatic Mutations in Cancer : COSMICLZTR1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDLZTR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch LZTR1
DgiDB (Drug Gene Interaction Database)LZTR1
DoCM (Curated mutations)LZTR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)LZTR1 (select a term)
intoGenLZTR1
Cancer3DLZTR1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600574    615670    616564   
Orphanet206    19649    19650    12482   
MedgenLZTR1
Genetic Testing Registry LZTR1
NextProtQ8N653 [Medical]
TSGene8216
GENETestsLZTR1
Target ValidationLZTR1
Huge Navigator LZTR1 [HugePedia]
snp3D : Map Gene to Disease8216
BioCentury BCIQLZTR1
ClinGenLZTR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8216
Chemical/Pharm GKB GenePA30506
Clinical trialLZTR1
Miscellaneous
canSAR (ICR)LZTR1 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineLZTR1
EVEXLZTR1
GoPubMedLZTR1
iHOPLZTR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:25:19 CEST 2017

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