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MADCAM1 (mucosal vascular addressin cell adhesion molecule 1)

Identity

Alias_symbol (synonym)MACAM1
Other alias
HGNC (Hugo) MADCAM1
LocusID (NCBI) 8174
Atlas_Id 55892
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 496490 and ends at 505343 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FOXK2 (17q25.3) / MADCAM1 (19p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(17;19)(q25;p13) FOXK2/MADCAM1


External links

Nomenclature
HGNC (Hugo)MADCAM1   6765
Cards
Entrez_Gene (NCBI)MADCAM1  8174  mucosal vascular addressin cell adhesion molecule 1
AliasesMACAM1
GeneCards (Weizmann)MADCAM1
Ensembl hg19 (Hinxton)ENSG00000099866 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000099866 [Gene_View]  ENSG00000099866 [Sequence]  chr19:496490-505343 [Contig_View]  MADCAM1 [Vega]
ICGC DataPortalENSG00000099866
TCGA cBioPortalMADCAM1
AceView (NCBI)MADCAM1
Genatlas (Paris)MADCAM1
WikiGenes8174
SOURCE (Princeton)MADCAM1
Genetics Home Reference (NIH)MADCAM1
Genomic and cartography
GoldenPath hg38 (UCSC)MADCAM1  -     chr19:496490-505343 +  19p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MADCAM1  -     19p13.3   [Description]    (hg19-Feb_2009)
EnsemblMADCAM1 - 19p13.3 [CytoView hg19]  MADCAM1 - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBIMADCAM1 [Mapview hg19]  MADCAM1 [Mapview hg38]
OMIM102670   
Gene and transcription
Genbank (Entrez)AK092211 AY732484 AY819760 BC136408 BC137506
RefSeq transcript (Entrez)NM_130760 NM_130762
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MADCAM1
Cluster EST : UnigeneHs.102598 [ NCBI ]
CGAP (NCI)Hs.102598
Alternative Splicing GalleryENSG00000099866
Gene ExpressionMADCAM1 [ NCBI-GEO ]   MADCAM1 [ EBI - ARRAY_EXPRESS ]   MADCAM1 [ SEEK ]   MADCAM1 [ MEM ]
Gene Expression Viewer (FireBrowse)MADCAM1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8174
GTEX Portal (Tissue expression)MADCAM1
Human Protein AtlasENSG00000099866-MADCAM1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13477   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13477  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13477
Splice isoforms : SwissVarQ13477
PhosPhoSitePlusQ13477
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Adhes-Ig-like    Ig-like_dom    Ig-like_dom_sf    Ig-like_fold    Ig_sub    MADCAM1   
Domain families : Pfam (Sanger)Adhes-Ig_like (PF09085)   
Domain families : Pfam (NCBI)pfam09085   
Domain families : Smart (EMBL)IG (SM00409)  
Domain structure : Prodom (Prabi Lyon)Adhes-Ig-like (PD336606)   
Conserved Domain (NCBI)MADCAM1
DMDM Disease mutations8174
Blocks (Seattle)MADCAM1
PDB (SRS)1BQS    1GSM    4HBQ    4HC1    4HCR    4HD9   
PDB (PDBSum)1BQS    1GSM    4HBQ    4HC1    4HCR    4HD9   
PDB (IMB)1BQS    1GSM    4HBQ    4HC1    4HCR    4HD9   
PDB (RSDB)1BQS    1GSM    4HBQ    4HC1    4HCR    4HD9   
Structural Biology KnowledgeBase1BQS    1GSM    4HBQ    4HC1    4HCR    4HD9   
SCOP (Structural Classification of Proteins)1BQS    1GSM    4HBQ    4HC1    4HCR    4HD9   
CATH (Classification of proteins structures)1BQS    1GSM    4HBQ    4HC1    4HCR    4HD9   
SuperfamilyQ13477
Human Protein Atlas [tissue]ENSG00000099866-MADCAM1 [tissue]
Peptide AtlasQ13477
HPRD00035
IPIIPI00289931   IPI00289933   IPI01015560   IPI01014056   IPI01010519   IPI00478318   IPI00915344   
Protein Interaction databases
DIP (DOE-UCLA)Q13477
IntAct (EBI)Q13477
FunCoupENSG00000099866
BioGRIDMADCAM1
STRING (EMBL)MADCAM1
ZODIACMADCAM1
Ontologies - Pathways
QuickGOQ13477
Ontology : AmiGOpositive regulation of leukocyte migration  plasma membrane  immune response  cell adhesion  cell-matrix adhesion  signal transduction  integrin-mediated signaling pathway  integrin-mediated signaling pathway  membrane  integral component of membrane  extracellular matrix organization  heterotypic cell-cell adhesion  heterotypic cell-cell adhesion  receptor clustering  regulation of immune response  leukocyte tethering or rolling  leukocyte tethering or rolling  integrin binding involved in cell-matrix adhesion  integrin binding involved in cell-matrix adhesion  positive regulation of lymphocyte migration  
Ontology : EGO-EBIpositive regulation of leukocyte migration  plasma membrane  immune response  cell adhesion  cell-matrix adhesion  signal transduction  integrin-mediated signaling pathway  integrin-mediated signaling pathway  membrane  integral component of membrane  extracellular matrix organization  heterotypic cell-cell adhesion  heterotypic cell-cell adhesion  receptor clustering  regulation of immune response  leukocyte tethering or rolling  leukocyte tethering or rolling  integrin binding involved in cell-matrix adhesion  integrin binding involved in cell-matrix adhesion  positive regulation of lymphocyte migration  
Pathways : KEGGCell adhesion molecules (CAMs)    Intestinal immune network for IgA production   
NDEx NetworkMADCAM1
Atlas of Cancer Signalling NetworkMADCAM1
Wikipedia pathwaysMADCAM1
Orthology - Evolution
OrthoDB8174
GeneTree (enSembl)ENSG00000099866
Phylogenetic Trees/Animal Genes : TreeFamMADCAM1
HOGENOMQ13477
Homologs : HomoloGeneMADCAM1
Homology/Alignments : Family Browser (UCSC)MADCAM1
Gene fusions - Rearrangements
Fusion : QuiverMADCAM1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMADCAM1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MADCAM1
dbVarMADCAM1
ClinVarMADCAM1
1000_GenomesMADCAM1 
Exome Variant ServerMADCAM1
ExAC (Exome Aggregation Consortium)ENSG00000099866
GNOMAD BrowserENSG00000099866
Varsome BrowserMADCAM1
Genetic variants : HAPMAP8174
Genomic Variants (DGV)MADCAM1 [DGVbeta]
DECIPHERMADCAM1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMADCAM1 
Mutations
ICGC Data PortalMADCAM1 
TCGA Data PortalMADCAM1 
Broad Tumor PortalMADCAM1
OASIS PortalMADCAM1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMADCAM1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMADCAM1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MADCAM1
DgiDB (Drug Gene Interaction Database)MADCAM1
DoCM (Curated mutations)MADCAM1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MADCAM1 (select a term)
intoGenMADCAM1
Cancer3DMADCAM1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM102670   
Orphanet
DisGeNETMADCAM1
MedgenMADCAM1
Genetic Testing Registry MADCAM1
NextProtQ13477 [Medical]
TSGene8174
GENETestsMADCAM1
Target ValidationMADCAM1
Huge Navigator MADCAM1 [HugePedia]
snp3D : Map Gene to Disease8174
BioCentury BCIQMADCAM1
ClinGenMADCAM1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8174
Chemical/Pharm GKB GenePA30522
Clinical trialMADCAM1
Miscellaneous
canSAR (ICR)MADCAM1 (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMADCAM1
EVEXMADCAM1
GoPubMedMADCAM1
iHOPMADCAM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Fri Dec 21 15:31:28 CET 2018

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