MAFG (MAF bZIP transcription factor G)

2003-02-01  

Identity

HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
hMAF
FUSION GENES

Other Information

Locus ID:

NCBI: 4097
MIM: 602020
HGNC: 6781
Ensembl: ENSG00000197063

Variants:

dbSNP: 4097
ClinVar: 4097
TCGA: ENSG00000197063
COSMIC: MAFG

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197063ENST00000357736O15525
ENSG00000197063ENST00000357736A0A024R8X1
ENSG00000197063ENST00000392366O15525
ENSG00000197063ENST00000392366A0A024R8X1
ENSG00000197063ENST00000574686I3L2F8

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Factors involved in megakaryocyte development and platelet productionREACTOMER-HSA-983231

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA283MAPK8GenePathwayassociated23922006
PA30621MAPK14GenePathwayassociated23922006

References

Pubmed IDYearTitleCitations
215555182011The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle.60
252195002014The BRAF oncoprotein functions through the transcriptional repressor MAFG to mediate the CpG Island Methylator phenotype.58
167161892006Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements.30
228556092012Induction of functional platelets from mouse and human fibroblasts by p45NF-E2/Maf.24
206898072010Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer.23
179282872007Negative regulation of inducible nitric-oxide synthase expression mediated through transforming growth factor-beta-dependent modulation of transcription factor TCF11.18
291588142017DNA Methylation of miR-7 is a Mechanism Involved in Platinum Response through MAFG Overexpression in Cancer Cells.14
241407082014Poly(ADP-ribose) polymerase-1 modulates Nrf2-dependent transcription.9
241184572014Small MAF genes variants and chronic myeloid leukemia.7
297338352018Mechanisms of MAFG Dysregulation in Cholestatic Liver Injury and Development of Liver Cancer.7

Citation

Dessen P

MAFG (MAF bZIP transcription factor G)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/41238/mafg