| Alias (NCBI) | NFE2U |
| P18 |
| HGNC (Hugo) |
MAFK |
| HGNC Alias symb | P18 |
| NFE2U |
| HGNC Alias name | basic-leucine zipper transcription factor MafK |
| erythroid transcription factor NF-E2 p18 subunit |
| nuclear factor erythroid-2, ubiquitous (p18) |
| HGNC Previous name | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K |
| LocusID (NCBI) |
7975 |
| Atlas_Id |
41239 |
| Location |
7p22.3 [Link to chromosome band 7p22] |
| Location_base_pair |
Starts at 1530702 and ends at 1543043 bp from pter ( according to hg38-Dec_2013) |
| Nomenclature |
|---|
| HGNC (Hugo) | MAFK 6782 |
| Cards |
|---|
| Entrez_Gene (NCBI) | MAFK MAF bZIP transcription factor K |
| Aliases | NFE2U; P18 |
| GeneCards (Weizmann) | MAFK |
| Ensembl hg19 (Hinxton) | ENSG00000198517 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000198517 [Gene_View] ENSG00000198517 [Sequence] chr7:1530702-1543043 [Contig_View] MAFK [Vega] |
| ICGC DataPortal | ENSG00000198517 |
| TCGA cBioPortal | MAFK |
| AceView (NCBI) | MAFK |
| Genatlas (Paris) | MAFK |
| SOURCE (Princeton) | MAFK |
| Genetics Home Reference (NIH) | MAFK |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | MAFK - chr7:1530702-1543043 + 7p22.3 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | MAFK - 7p22.3 [Description] (hg19-Feb_2009) |
| GoldenPath | MAFK - 7p22.3 [CytoView hg19] MAFK - 7p22.3 [CytoView hg38] |
| ImmunoBase | ENSG00000198517 |
| genome Data Viewer NCBI | MAFK [Mapview hg19] |
| OMIM | 600197 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AF059194 AK056767 AK092414 AL831913 BC012777 |
| RefSeq transcript (Entrez) | NM_002360 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | MAFK |
| Alternative Splicing Gallery | ENSG00000198517 |
| Gene Expression | MAFK [ NCBI-GEO ] MAFK [ EBI - ARRAY_EXPRESS ]
MAFK [ SEEK ] MAFK [ MEM ] |
| Gene Expression Viewer (FireBrowse) | MAFK [ Firebrowse - Broad ] |
| Genevisible | Expression of MAFK in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 7975 |
| GTEX Portal (Tissue expression) | MAFK |
| Human Protein Atlas | ENSG00000198517-MAFK [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | O60675 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | O60675 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | O60675 |
| Splice isoforms : SwissVar | O60675 |
| PhosPhoSitePlus | O60675 |
| Domaine pattern : Prosite (Expaxy) | BZIP (PS50217) |
| Domains : Interpro (EBI) | bZIP bZIP_Maf MafK TF_DNA-bd_sf Transcription_factor_Maf_fam |
| Domain families : Pfam (Sanger) | bZIP_Maf (PF03131) |
| Domain families : Pfam (NCBI) | pfam03131 |
| Domain families : Smart (EMBL) | BRLZ (SM00338) |
| Conserved Domain (NCBI) | MAFK |
| Blocks (Seattle) | MAFK |
| Superfamily | O60675 |
| Human Protein Atlas [tissue] | ENSG00000198517-MAFK [tissue] |
| Peptide Atlas | O60675 |
| HPRD | 02561 |
| IPI | IPI00031018 IPI00386085 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | O60675 |
| IntAct (EBI) | O60675 |
| BioGRID | MAFK |
| STRING (EMBL) | MAFK |
| ZODIAC | MAFK |
| Ontologies - Pathways |
|---|
| QuickGO | O60675 |
| Ontology : AmiGO | negative regulation of transcription by RNA polymerase II nuclear chromatin transcription regulatory region sequence-specific DNA binding RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific transcription cofactor binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleoplasm nucleoplasm nervous system development blood coagulation host cell nucleus sequence-specific DNA binding sequence-specific DNA binding RING-like zinc finger domain binding |
| Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II nuclear chromatin transcription regulatory region sequence-specific DNA binding RNA polymerase II proximal promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific transcription cofactor binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleoplasm nucleoplasm nervous system development blood coagulation host cell nucleus sequence-specific DNA binding sequence-specific DNA binding RING-like zinc finger domain binding |
| NDEx Network | MAFK |
| Atlas of Cancer Signalling Network | MAFK |
| Wikipedia pathways | MAFK |
| Orthology - Evolution |
|---|
| OrthoDB | 7975 |
| GeneTree (enSembl) | ENSG00000198517 |
| Phylogenetic Trees/Animal Genes : TreeFam | MAFK |
| HOGENOM | O60675 |
| Homologs : HomoloGene | MAFK |
| Homology/Alignments : Family Browser (UCSC) | MAFK |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | MAFK |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | MAFK [hg38] |
| dbVar | MAFK |
| ClinVar | MAFK |
| Monarch | MAFK |
| 1000_Genomes | MAFK |
| Exome Variant Server | MAFK |
| GNOMAD Browser | ENSG00000198517 |
| Varsome Browser | MAFK |
| Genomic Variants (DGV) | MAFK [DGVbeta] |
| DECIPHER | MAFK [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | MAFK |
| Mutations |
|---|
| ICGC Data Portal | MAFK |
| TCGA Data Portal | MAFK |
| Broad Tumor Portal | MAFK |
| OASIS Portal | MAFK [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | MAFK [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | MAFK |
| Mutations and Diseases : HGMD | MAFK |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search MAFK |
| DgiDB (Drug Gene Interaction Database) | MAFK |
| DoCM (Curated mutations) | MAFK (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | MAFK (select a term) |
| intoGen | MAFK |
| Cancer3D | MAFK(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 600197 |
| Orphanet | |
| DisGeNET | MAFK |
| Medgen | MAFK |
| Genetic Testing Registry | MAFK
|
| NextProt | O60675 [Medical] |
| GENETests | MAFK |
| Target Validation | MAFK |
| Huge Navigator |
MAFK [HugePedia] |
| ClinGen | MAFK |
| Clinical trials, drugs, therapy |
|---|
| MyCancerGenome | MAFK |
| Protein Interactions : CTD | |
| Pharm GKB Gene | PA30540 |
| Pharm GKB Pathways | PA165985892 |
| Pharos | O60675 |
| Clinical trial | MAFK |
| Miscellaneous |
|---|
| canSAR (ICR) | MAFK (select the gene name) |
| Harmonizome | MAFK |
| DataMed Index | MAFK |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 42 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| EVEX | MAFK |
