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MAGEA1 (MAGE family member A1)

Identity

Alias (NCBI)CT1.1
MAGE1
HGNC (Hugo) MAGEA1
HGNC Alias symbMGC9326
CT1.1
HGNC Alias namemelanoma-associated antigen 1
 melanoma-associated antigen MZ2-E
 melanoma antigen MAGE-1
 melanoma antigen family A 1
 cancer/testis antigen family 1, member 1
HGNC Previous nameMAGE1
HGNC Previous namemelanoma antigen family A, 1 (directs expression of antigen MZ2-E)
 melanoma antigen family A1
LocusID (NCBI) 4100
Atlas_Id 41241
Location Xq28  [Link to chromosome band Xq28]
Location_base_pair Starts at 153179284 and ends at 153183880 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)MAGEA1   6796
Cards
Entrez_Gene (NCBI)MAGEA1    MAGE family member A1
AliasesCT1.1; MAGE1
GeneCards (Weizmann)MAGEA1
Ensembl hg19 (Hinxton)ENSG00000198681 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198681 [Gene_View]  ENSG00000198681 [Sequence]  chrX:153179284-153183880 [Contig_View]  MAGEA1 [Vega]
ICGC DataPortalENSG00000198681
TCGA cBioPortalMAGEA1
AceView (NCBI)MAGEA1
Genatlas (Paris)MAGEA1
SOURCE (Princeton)MAGEA1
Genetics Home Reference (NIH)MAGEA1
Genomic and cartography
GoldenPath hg38 (UCSC)MAGEA1  -     chrX:153179284-153183880 +  Xq28   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MAGEA1  -     Xq28   [Description]    (hg19-Feb_2009)
GoldenPathMAGEA1 - Xq28 [CytoView hg19]  MAGEA1 - Xq28 [CytoView hg38]
ImmunoBaseENSG00000198681
Genome Data Viewer NCBIMAGEA1 [Mapview hg19]  
OMIM300016   
Gene and transcription
Genbank (Entrez)AF463515 AK314979 AY148486 BC017555 BP314195
RefSeq transcript (Entrez)NM_004988
Consensus coding sequences : CCDS (NCBI)MAGEA1
Gene ExpressionMAGEA1 [ NCBI-GEO ]   MAGEA1 [ EBI - ARRAY_EXPRESS ]   MAGEA1 [ SEEK ]   MAGEA1 [ MEM ]
Gene Expression Viewer (FireBrowse)MAGEA1 [ Firebrowse - Broad ]
GenevisibleExpression of MAGEA1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4100
GTEX Portal (Tissue expression)MAGEA1
Human Protein AtlasENSG00000198681-MAGEA1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP43355   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP43355  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP43355
PhosPhoSitePlusP43355
Domaine pattern : Prosite (Expaxy)MAGE (PS50838)   
Domains : Interpro (EBI)MAGE    MAGE_N    MAGE_WH1    MAGE_WH2    MAGEA1    MHD_dom   
Domain families : Pfam (Sanger)MAGE (PF01454)    MAGE_N (PF12440)   
Domain families : Pfam (NCBI)pfam01454    pfam12440   
Domain families : Smart (EMBL)MAGE (SM01373)  MAGE_N (SM01392)  
Conserved Domain (NCBI)MAGEA1
PDB (RSDB)1W72    3BO8   
PDB Europe1W72    3BO8   
PDB (PDBSum)1W72    3BO8   
PDB (IMB)1W72    3BO8   
Structural Biology KnowledgeBase1W72    3BO8   
SCOP (Structural Classification of Proteins)1W72    3BO8   
CATH (Classification of proteins structures)1W72    3BO8   
SuperfamilyP43355
AlphaFold pdb e-kbP43355   
Human Protein Atlas [tissue]ENSG00000198681-MAGEA1 [tissue]
HPRD02059
Protein Interaction databases
DIP (DOE-UCLA)P43355
IntAct (EBI)P43355
BioGRIDMAGEA1
STRING (EMBL)MAGEA1
ZODIACMAGEA1
Ontologies - Pathways
QuickGOP43355
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  protein binding  nucleus  cytoplasm  plasma membrane  histone deacetylase binding  negative regulation of Notch signaling pathway  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  protein binding  nucleus  cytoplasm  plasma membrane  histone deacetylase binding  negative regulation of Notch signaling pathway  
NDEx NetworkMAGEA1
Atlas of Cancer Signalling NetworkMAGEA1
Wikipedia pathwaysMAGEA1
Orthology - Evolution
OrthoDB4100
GeneTree (enSembl)ENSG00000198681
Phylogenetic Trees/Animal Genes : TreeFamMAGEA1
Homologs : HomoloGeneMAGEA1
Homology/Alignments : Family Browser (UCSC)MAGEA1
Gene fusions - Rearrangements
Fusion : QuiverMAGEA1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMAGEA1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MAGEA1
dbVarMAGEA1
ClinVarMAGEA1
MonarchMAGEA1
1000_GenomesMAGEA1 
Exome Variant ServerMAGEA1
GNOMAD BrowserENSG00000198681
Varsome BrowserMAGEA1
ACMGMAGEA1 variants
VarityP43355
Genomic Variants (DGV)MAGEA1 [DGVbeta]
DECIPHERMAGEA1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMAGEA1 
Mutations
ICGC Data PortalMAGEA1 
TCGA Data PortalMAGEA1 
Broad Tumor PortalMAGEA1
OASIS PortalMAGEA1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMAGEA1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMAGEA1
Mutations and Diseases : HGMDMAGEA1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMAGEA1
DgiDB (Drug Gene Interaction Database)MAGEA1
DoCM (Curated mutations)MAGEA1
CIViC (Clinical Interpretations of Variants in Cancer)MAGEA1
Cancer3DMAGEA1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300016   
Orphanet
DisGeNETMAGEA1
MedgenMAGEA1
Genetic Testing Registry MAGEA1
NextProtP43355 [Medical]
GENETestsMAGEA1
Target ValidationMAGEA1
Huge Navigator MAGEA1 [HugePedia]
ClinGenMAGEA1
Clinical trials, drugs, therapy
MyCancerGenomeMAGEA1
Protein Interactions : CTDMAGEA1
Pharm GKB GenePA30542
PharosP43355
Clinical trialMAGEA1
Miscellaneous
canSAR (ICR)MAGEA1
HarmonizomeMAGEA1
DataMed IndexMAGEA1
Probes
Litterature
PubMed82 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMAGEA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:17:27 CEST 2021

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