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MAGEA2B (MAGE family member A2B)

Identity

Alias_namesmelanoma antigen family A2B
Alias_symbol (synonym)MAGEA2b
MAGE2
MGC16973
MAGEA2
Other aliasCT1.2
HGNC (Hugo) MAGEA2B
LocusID (NCBI) 266740
Atlas_Id 41246
Location Xq28  [Link to chromosome band Xq28]
Location_base_pair Starts at 152714586 and ends at 152718607 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MAGEA2B   19340
Cards
Entrez_Gene (NCBI)MAGEA2B  266740  MAGE family member A2B
AliasesCT1.2; MAGE2
GeneCards (Weizmann)MAGEA2B
Ensembl hg19 (Hinxton)ENSG00000183305 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183305 [Gene_View]  ENSG00000183305 [Sequence]  chrX:152714586-152718607 [Contig_View]  MAGEA2B [Vega]
ICGC DataPortalENSG00000183305
TCGA cBioPortalMAGEA2B
AceView (NCBI)MAGEA2B
Genatlas (Paris)MAGEA2B
WikiGenes266740
SOURCE (Princeton)MAGEA2B
Genetics Home Reference (NIH)MAGEA2B
Genomic and cartography
GoldenPath hg38 (UCSC)MAGEA2B  -     chrX:152714586-152718607 +  Xq28   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MAGEA2B  -     Xq28   [Description]    (hg19-Feb_2009)
EnsemblMAGEA2B - Xq28 [CytoView hg19]  MAGEA2B - Xq28 [CytoView hg38]
Mapping of homologs : NCBIMAGEA2B [Mapview hg19]  MAGEA2B [Mapview hg38]
OMIM300549   
Gene and transcription
Genbank (Entrez)AK290443 BC013098 BC063681 BC108720 BC109188
RefSeq transcript (Entrez)NM_001321400 NM_001321401 NM_001321402 NM_001321403 NM_001321404 NM_153488
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MAGEA2B
Cluster EST : UnigeneHs.713061 [ NCBI ]
CGAP (NCI)Hs.713061
Alternative Splicing GalleryENSG00000183305
Gene ExpressionMAGEA2B [ NCBI-GEO ]   MAGEA2B [ EBI - ARRAY_EXPRESS ]   MAGEA2B [ SEEK ]   MAGEA2B [ MEM ]
Gene Expression Viewer (FireBrowse)MAGEA2B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)266740
GTEX Portal (Tissue expression)MAGEA2B
Human Protein AtlasENSG00000183305-MAGEA2B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP43356   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP43356  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP43356
Splice isoforms : SwissVarP43356
PhosPhoSitePlusP43356
Domaine pattern : Prosite (Expaxy)MAGE (PS50838)   
Domains : Interpro (EBI)MAGE    MAGE_N    MHD_dom   
Domain families : Pfam (Sanger)MAGE (PF01454)    MAGE_N (PF12440)   
Domain families : Pfam (NCBI)pfam01454    pfam12440   
Domain families : Smart (EMBL)MAGE (SM01373)  MAGE_N (SM01392)  
Conserved Domain (NCBI)MAGEA2B
DMDM Disease mutations266740
Blocks (Seattle)MAGEA2B
SuperfamilyP43356
Human Protein Atlas [tissue]ENSG00000183305-MAGEA2B [tissue]
Peptide AtlasP43356
HPRD14347
IPIIPI00018038   IPI00916266   IPI00916312   IPI00916018   IPI00845350   IPI00916730   IPI00872534   
Protein Interaction databases
DIP (DOE-UCLA)P43356
IntAct (EBI)P43356
FunCoupENSG00000183305
BioGRIDMAGEA2B
STRING (EMBL)MAGEA2B
ZODIACMAGEA2B
Ontologies - Pathways
QuickGOP43356
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  protein binding  nucleus  transcription, DNA-templated  PML body  ubiquitin protein ligase binding  negative regulation of protein sumoylation  histone deacetylase binding  cellular protein catabolic process  positive regulation of ubiquitin-protein transferase activity  repressing transcription factor binding  signal transduction by p53 class mediator  cellular senescence  negative regulation of protein acetylation  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  protein binding  nucleus  transcription, DNA-templated  PML body  ubiquitin protein ligase binding  negative regulation of protein sumoylation  histone deacetylase binding  cellular protein catabolic process  positive regulation of ubiquitin-protein transferase activity  repressing transcription factor binding  signal transduction by p53 class mediator  cellular senescence  negative regulation of protein acetylation  
NDEx NetworkMAGEA2B
Atlas of Cancer Signalling NetworkMAGEA2B
Wikipedia pathwaysMAGEA2B
Orthology - Evolution
OrthoDB266740
GeneTree (enSembl)ENSG00000183305
Phylogenetic Trees/Animal Genes : TreeFamMAGEA2B
HOVERGENP43356
HOGENOMP43356
Homologs : HomoloGeneMAGEA2B
Homology/Alignments : Family Browser (UCSC)MAGEA2B
Gene fusions - Rearrangements
Fusion : QuiverMAGEA2B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMAGEA2B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MAGEA2B
dbVarMAGEA2B
ClinVarMAGEA2B
1000_GenomesMAGEA2B 
Exome Variant ServerMAGEA2B
ExAC (Exome Aggregation Consortium)ENSG00000183305
GNOMAD BrowserENSG00000183305
Varsome BrowserMAGEA2B
Genetic variants : HAPMAP266740
Genomic Variants (DGV)MAGEA2B [DGVbeta]
DECIPHERMAGEA2B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMAGEA2B 
Mutations
ICGC Data PortalMAGEA2B 
TCGA Data PortalMAGEA2B 
Broad Tumor PortalMAGEA2B
OASIS PortalMAGEA2B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMAGEA2B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMAGEA2B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MAGEA2B
DgiDB (Drug Gene Interaction Database)MAGEA2B
DoCM (Curated mutations)MAGEA2B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MAGEA2B (select a term)
intoGenMAGEA2B
Cancer3DMAGEA2B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300549   
Orphanet
DisGeNETMAGEA2B
MedgenMAGEA2B
Genetic Testing Registry MAGEA2B
NextProtP43356 [Medical]
TSGene266740
GENETestsMAGEA2B
Target ValidationMAGEA2B
Huge Navigator MAGEA2B [HugePedia]
snp3D : Map Gene to Disease266740
BioCentury BCIQMAGEA2B
ClinGenMAGEA2B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD266740
Chemical/Pharm GKB GenePA134906398
Clinical trialMAGEA2B
Miscellaneous
canSAR (ICR)MAGEA2B (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMAGEA2B
EVEXMAGEA2B
GoPubMedMAGEA2B
iHOPMAGEA2B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 27 11:33:47 CEST 2018

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