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MAGEA4 (MAGE family member A4)

Identity

Alias_namesMAGE4
melanoma antigen family A4
Alias_symbol (synonym)MAGE4A
MAGE4B
MAGE-41
MAGE-X2
MGC21336
CT1.4
Other alias
HGNC (Hugo) MAGEA4
LocusID (NCBI) 4103
Atlas_Id 515
Location Xq28  [Link to chromosome band Xq28]
Location_base_pair Starts at 151912889 and ends at 151925170 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MAGEA4 (Xq28) / SMPD1 (11p15.4)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Testis: Spermatocytic seminoma


External links

Nomenclature
HGNC (Hugo)MAGEA4   6802
Cards
Entrez_Gene (NCBI)MAGEA4  4103  MAGE family member A4
AliasesCT1.4; MAGE-41; MAGE-X2; MAGE4; 
MAGE4A; MAGE4B
GeneCards (Weizmann)MAGEA4
Ensembl hg19 (Hinxton)ENSG00000147381 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000147381 [Gene_View]  chrX:151912889-151925170 [Contig_View]  MAGEA4 [Vega]
ICGC DataPortalENSG00000147381
TCGA cBioPortalMAGEA4
AceView (NCBI)MAGEA4
Genatlas (Paris)MAGEA4
WikiGenes4103
SOURCE (Princeton)MAGEA4
Genetics Home Reference (NIH)MAGEA4
Genomic and cartography
GoldenPath hg38 (UCSC)MAGEA4  -     chrX:151912889-151925170 +  Xq28   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MAGEA4  -     Xq28   [Description]    (hg19-Feb_2009)
EnsemblMAGEA4 - Xq28 [CytoView hg19]  MAGEA4 - Xq28 [CytoView hg38]
Mapping of homologs : NCBIMAGEA4 [Mapview hg19]  MAGEA4 [Mapview hg38]
OMIM300175   
Gene and transcription
Genbank (Entrez)AK300179 AK313862 AY954624 BC017723 BC096712
RefSeq transcript (Entrez)NM_001011548 NM_001011549 NM_001011550 NM_002362
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MAGEA4
Cluster EST : UnigeneHs.37107 [ NCBI ]
CGAP (NCI)Hs.37107
Alternative Splicing GalleryENSG00000147381
Gene ExpressionMAGEA4 [ NCBI-GEO ]   MAGEA4 [ EBI - ARRAY_EXPRESS ]   MAGEA4 [ SEEK ]   MAGEA4 [ MEM ]
Gene Expression Viewer (FireBrowse)MAGEA4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4103
GTEX Portal (Tissue expression)MAGEA4
Protein : pattern, domain, 3D structure
UniProt/SwissProtP43358   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP43358  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP43358
Splice isoforms : SwissVarP43358
PhosPhoSitePlusP43358
Domaine pattern : Prosite (Expaxy)MAGE (PS50838)   
Domains : Interpro (EBI)MAGE_N    MAGEA4/MAGEA5    MHD_dom   
Domain families : Pfam (Sanger)MAGE (PF01454)    MAGE_N (PF12440)   
Domain families : Pfam (NCBI)pfam01454    pfam12440   
Domain families : Smart (EMBL)MAGE (SM01373)  MAGE_N (SM01392)  
Conserved Domain (NCBI)MAGEA4
DMDM Disease mutations4103
Blocks (Seattle)MAGEA4
PDB (SRS)1I4F    2WA0   
PDB (PDBSum)1I4F    2WA0   
PDB (IMB)1I4F    2WA0   
PDB (RSDB)1I4F    2WA0   
Structural Biology KnowledgeBase1I4F    2WA0   
SCOP (Structural Classification of Proteins)1I4F    2WA0   
CATH (Classification of proteins structures)1I4F    2WA0   
SuperfamilyP43358
Human Protein AtlasENSG00000147381
Peptide AtlasP43358
HPRD02167
IPIIPI00910524   IPI00642005   IPI00952837   IPI00643190   IPI00607853   
Protein Interaction databases
DIP (DOE-UCLA)P43358
IntAct (EBI)P43358
FunCoupENSG00000147381
BioGRIDMAGEA4
STRING (EMBL)MAGEA4
ZODIACMAGEA4
Ontologies - Pathways
QuickGOP43358
Ontology : AmiGOmolecular_function  protein binding  cellular_component  biological_process  
Ontology : EGO-EBImolecular_function  protein binding  cellular_component  biological_process  
NDEx NetworkMAGEA4
Atlas of Cancer Signalling NetworkMAGEA4
Wikipedia pathwaysMAGEA4
Orthology - Evolution
OrthoDB4103
GeneTree (enSembl)ENSG00000147381
Phylogenetic Trees/Animal Genes : TreeFamMAGEA4
HOVERGENP43358
HOGENOMP43358
Homologs : HomoloGeneMAGEA4
Homology/Alignments : Family Browser (UCSC)MAGEA4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMAGEA4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MAGEA4
dbVarMAGEA4
ClinVarMAGEA4
1000_GenomesMAGEA4 
Exome Variant ServerMAGEA4
ExAC (Exome Aggregation Consortium)MAGEA4 (select the gene name)
Genetic variants : HAPMAP4103
Genomic Variants (DGV)MAGEA4 [DGVbeta]
DECIPHERMAGEA4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMAGEA4 
Mutations
ICGC Data PortalMAGEA4 
TCGA Data PortalMAGEA4 
Broad Tumor PortalMAGEA4
OASIS PortalMAGEA4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMAGEA4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMAGEA4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch MAGEA4
DgiDB (Drug Gene Interaction Database)MAGEA4
DoCM (Curated mutations)MAGEA4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MAGEA4 (select a term)
intoGenMAGEA4
Cancer3DMAGEA4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300175   
Orphanet
MedgenMAGEA4
Genetic Testing Registry MAGEA4
NextProtP43358 [Medical]
TSGene4103
GENETestsMAGEA4
Target ValidationMAGEA4
Huge Navigator MAGEA4 [HugePedia]
snp3D : Map Gene to Disease4103
BioCentury BCIQMAGEA4
ClinGenMAGEA4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4103
Chemical/Pharm GKB GenePA30548
Clinical trialMAGEA4
Miscellaneous
canSAR (ICR)MAGEA4 (select the gene name)
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMAGEA4
EVEXMAGEA4
GoPubMedMAGEA4
iHOPMAGEA4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:06:07 CEST 2017

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