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MAGEA4 (MAGE family member A4)

Identity

Alias (NCBI)CT1.4
MAGE-41
MAGE-X2
MAGE4
MAGE4A
MAGE4B
HGNC (Hugo) MAGEA4
HGNC Alias symbMAGE4A
MAGE4B
MAGE-41
MAGE-X2
MGC21336
CT1.4
HGNC Alias namemelanoma-associated antigen 4
 cancer/testis antigen family 1, member 4
HGNC Previous nameMAGE4
HGNC Previous namemelanoma antigen family A4
LocusID (NCBI) 4103
Atlas_Id 515
Location Xq28  [Link to chromosome band Xq28]
Location_base_pair Starts at 151916237 and ends at 151925170 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MAGEA4 (Xq28) / SMPD1 (11p15.4)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Testis: Spermatocytic seminoma


External links

Nomenclature
HGNC (Hugo)MAGEA4   6802
Cards
Entrez_Gene (NCBI)MAGEA4    MAGE family member A4
AliasesCT1.4; MAGE-41; MAGE-X2; MAGE4; 
MAGE4A; MAGE4B
GeneCards (Weizmann)MAGEA4
Ensembl hg19 (Hinxton)ENSG00000147381 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000147381 [Gene_View]  ENSG00000147381 [Sequence]  chrX:151916237-151925170 [Contig_View]  MAGEA4 [Vega]
ICGC DataPortalENSG00000147381
TCGA cBioPortalMAGEA4
AceView (NCBI)MAGEA4
Genatlas (Paris)MAGEA4
SOURCE (Princeton)MAGEA4
Genetics Home Reference (NIH)MAGEA4
Genomic and cartography
GoldenPath hg38 (UCSC)MAGEA4  -     chrX:151916237-151925170 +  Xq28   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MAGEA4  -     Xq28   [Description]    (hg19-Feb_2009)
GoldenPathMAGEA4 - Xq28 [CytoView hg19]  MAGEA4 - Xq28 [CytoView hg38]
ImmunoBaseENSG00000147381
genome Data Viewer NCBIMAGEA4 [Mapview hg19]  
OMIM300175   
Gene and transcription
Genbank (Entrez)AK300179 AK313862 AY954624 BC017723 BC096712
RefSeq transcript (Entrez)NM_001011548 NM_001011549 NM_001011550 NM_002362
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MAGEA4
Alternative Splicing GalleryENSG00000147381
Gene ExpressionMAGEA4 [ NCBI-GEO ]   MAGEA4 [ EBI - ARRAY_EXPRESS ]   MAGEA4 [ SEEK ]   MAGEA4 [ MEM ]
Gene Expression Viewer (FireBrowse)MAGEA4 [ Firebrowse - Broad ]
GenevisibleExpression of MAGEA4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4103
GTEX Portal (Tissue expression)MAGEA4
Human Protein AtlasENSG00000147381-MAGEA4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP43358   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP43358  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP43358
Splice isoforms : SwissVarP43358
PhosPhoSitePlusP43358
Domaine pattern : Prosite (Expaxy)MAGE (PS50838)   
Domains : Interpro (EBI)MAGE    MAGE_N    MAGE_WH1    MAGE_WH2    MAGEA4/MAGEA5    MHD_dom   
Domain families : Pfam (Sanger)MAGE (PF01454)    MAGE_N (PF12440)   
Domain families : Pfam (NCBI)pfam01454    pfam12440   
Domain families : Smart (EMBL)MAGE (SM01373)  MAGE_N (SM01392)  
Conserved Domain (NCBI)MAGEA4
Blocks (Seattle)MAGEA4
PDB (RSDB)1I4F    2WA0   
PDB Europe1I4F    2WA0   
PDB (PDBSum)1I4F    2WA0   
PDB (IMB)1I4F    2WA0   
Structural Biology KnowledgeBase1I4F    2WA0   
SCOP (Structural Classification of Proteins)1I4F    2WA0   
CATH (Classification of proteins structures)1I4F    2WA0   
SuperfamilyP43358
Human Protein Atlas [tissue]ENSG00000147381-MAGEA4 [tissue]
Peptide AtlasP43358
HPRD02167
IPIIPI00910524   IPI00642005   IPI00952837   IPI00643190   IPI00607853   
Protein Interaction databases
DIP (DOE-UCLA)P43358
IntAct (EBI)P43358
BioGRIDMAGEA4
STRING (EMBL)MAGEA4
ZODIACMAGEA4
Ontologies - Pathways
QuickGOP43358
Ontology : AmiGOmolecular_function  protein binding  cellular_component  biological_process  
Ontology : EGO-EBImolecular_function  protein binding  cellular_component  biological_process  
NDEx NetworkMAGEA4
Atlas of Cancer Signalling NetworkMAGEA4
Wikipedia pathwaysMAGEA4
Orthology - Evolution
OrthoDB4103
GeneTree (enSembl)ENSG00000147381
Phylogenetic Trees/Animal Genes : TreeFamMAGEA4
HOGENOMP43358
Homologs : HomoloGeneMAGEA4
Homology/Alignments : Family Browser (UCSC)MAGEA4
Gene fusions - Rearrangements
Fusion : QuiverMAGEA4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMAGEA4 [hg38]
dbVarMAGEA4
ClinVarMAGEA4
MonarchMAGEA4
1000_GenomesMAGEA4 
Exome Variant ServerMAGEA4
GNOMAD BrowserENSG00000147381
Varsome BrowserMAGEA4
Genomic Variants (DGV)MAGEA4 [DGVbeta]
DECIPHERMAGEA4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMAGEA4 
Mutations
ICGC Data PortalMAGEA4 
TCGA Data PortalMAGEA4 
Broad Tumor PortalMAGEA4
OASIS PortalMAGEA4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMAGEA4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMAGEA4
Mutations and Diseases : HGMDMAGEA4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch MAGEA4
DgiDB (Drug Gene Interaction Database)MAGEA4
DoCM (Curated mutations)MAGEA4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MAGEA4 (select a term)
intoGenMAGEA4
Cancer3DMAGEA4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300175   
Orphanet
DisGeNETMAGEA4
MedgenMAGEA4
Genetic Testing Registry MAGEA4
NextProtP43358 [Medical]
GENETestsMAGEA4
Target ValidationMAGEA4
Huge Navigator MAGEA4 [HugePedia]
ClinGenMAGEA4
Clinical trials, drugs, therapy
MyCancerGenomeMAGEA4
Protein Interactions : CTD
Pharm GKB GenePA30548
PharosP43358
Clinical trialMAGEA4
Miscellaneous
canSAR (ICR)MAGEA4 (select the gene name)
HarmonizomeMAGEA4
DataMed IndexMAGEA4
Probes
Litterature
PubMed68 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMAGEA4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jan 1 18:23:45 CET 2021

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