MAGED2 (MAGE family member D2)

2003-11-01  

Identity

HGNC
LOCATION
Xp11.21
LOCUSID
ALIAS
11B6,BARTS5,BCG-1,BCG1,HCA10,MAGE-D2
FUSION GENES

Other Information

Locus ID:

NCBI: 10916
MIM: 300470
HGNC: 16353
Ensembl: ENSG00000102316

Variants:

dbSNP: 10916
ClinVar: 10916
TCGA: ENSG00000102316
COSMIC: MAGED2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102316ENST00000218439Q9UNF1
ENSG00000102316ENST00000218439A0A024R9Y7
ENSG00000102316ENST00000347546Q5H909
ENSG00000102316ENST00000375053Q9UNF1
ENSG00000102316ENST00000375053A0A024R9Y7
ENSG00000102316ENST00000375058Q9UNF1
ENSG00000102316ENST00000375058A0A024R9Y7
ENSG00000102316ENST00000375060Q5H907
ENSG00000102316ENST00000375068Q9UNF1
ENSG00000102316ENST00000375068A0A024R9Y7
ENSG00000102316ENST00000396224Q9UNF1
ENSG00000102316ENST00000396224A0A024R9Y7
ENSG00000102316ENST00000627068Q5H907

Expression (GTEx)

0
50
100
150
200
250
300
350
400

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Platelet activation, signaling and aggregationREACTOMER-HSA-76002
Response to elevated platelet cytosolic Ca2+REACTOMER-HSA-76005
Platelet degranulationREACTOMER-HSA-114608

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
271207712016Polyhydramnios, Transient Antenatal Bartter's Syndrome, and MAGED2 Mutations.20
151625112004Comparative expression analysis of the MAGED genes during embryogenesis and brain development.12
257433302016The Expression of Melanoma-Associated Antigen D2 Both in Surgically Resected and Serum Samples Serves as Clinically Relevant Biomarker of Gastric Cancer Progression.12
180951542008Use of expression data and the CGEMS genome-wide breast cancer association study to identify genes that may modify risk in BRCA1/2 mutation carriers.9
227918142012The melanoma-associated antigen MAGE-D2 suppresses TRAIL receptor 2 and protects against TRAIL-induced apoptosis in human melanoma cells.9
179124492007MAGED2: a novel p53-dissociator.7
118568872001Expression pattern and further characterization of human MAGED2 and identification of rodent orthologues.4
291467022018Prevalence of Novel MAGED2 Mutations in Antenatal Bartter Syndrome.3
154650022004Identification of a novel MAGE D2 antisense RNA transcript in human tissues.2

Citation

Dessen P

MAGED2 (MAGE family member D2)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/41262/maged2