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MAGEL2 (MAGE family member L2)

Identity

Alias_namesNDNL1
MAGE-like 2
melanoma antigen family L2
Alias_symbol (synonym)nM15
Other aliasPWLS
SHFYNG
HGNC (Hugo) MAGEL2
LocusID (NCBI) 54551
Atlas_Id 55067
Location 15q11.2  [Link to chromosome band 15q11]
Location_base_pair Starts at 23643549 and ends at 23647846 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MAGEL2   6814
LRG (Locus Reference Genomic)LRG_1046
Cards
Entrez_Gene (NCBI)MAGEL2  54551  MAGE family member L2
AliasesNDNL1; PWLS; SHFYNG; nM15
GeneCards (Weizmann)MAGEL2
Ensembl hg19 (Hinxton)ENSG00000254585 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000254585 [Gene_View]  chr15:23643549-23647846 [Contig_View]  MAGEL2 [Vega]
ICGC DataPortalENSG00000254585
TCGA cBioPortalMAGEL2
AceView (NCBI)MAGEL2
Genatlas (Paris)MAGEL2
WikiGenes54551
SOURCE (Princeton)MAGEL2
Genetics Home Reference (NIH)MAGEL2
Genomic and cartography
GoldenPath hg38 (UCSC)MAGEL2  -     chr15:23643549-23647846 -  15q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MAGEL2  -     15q11.2   [Description]    (hg19-Feb_2009)
EnsemblMAGEL2 - 15q11.2 [CytoView hg19]  MAGEL2 - 15q11.2 [CytoView hg38]
Mapping of homologs : NCBIMAGEL2 [Mapview hg19]  MAGEL2 [Mapview hg38]
OMIM176270   605283   615547   
Gene and transcription
Genbank (Entrez)AJ243531 BC035839 BC063834 BC112257 BC112259
RefSeq transcript (Entrez)NM_019066
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MAGEL2
Cluster EST : UnigeneHs.141496 [ NCBI ]
CGAP (NCI)Hs.141496
Alternative Splicing GalleryENSG00000254585
Gene ExpressionMAGEL2 [ NCBI-GEO ]   MAGEL2 [ EBI - ARRAY_EXPRESS ]   MAGEL2 [ SEEK ]   MAGEL2 [ MEM ]
Gene Expression Viewer (FireBrowse)MAGEL2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54551
GTEX Portal (Tissue expression)MAGEL2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UJ55   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UJ55  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UJ55
Splice isoforms : SwissVarQ9UJ55
PhosPhoSitePlusQ9UJ55
Domaine pattern : Prosite (Expaxy)MAGE (PS50838)   
Domains : Interpro (EBI)MHD_dom   
Domain families : Pfam (Sanger)MAGE (PF01454)   
Domain families : Pfam (NCBI)pfam01454   
Domain families : Smart (EMBL)MAGE (SM01373)  
Conserved Domain (NCBI)MAGEL2
DMDM Disease mutations54551
Blocks (Seattle)MAGEL2
SuperfamilyQ9UJ55
Human Protein AtlasENSG00000254585
Peptide AtlasQ9UJ55
HPRD12008
IPIIPI00005120   
Protein Interaction databases
DIP (DOE-UCLA)Q9UJ55
IntAct (EBI)Q9UJ55
FunCoupENSG00000254585
BioGRIDMAGEL2
STRING (EMBL)MAGEL2
ZODIACMAGEL2
Ontologies - Pathways
QuickGOQ9UJ55
Ontology : AmiGOubiquitin-protein transferase activity  protein binding  nucleus  endosome  early endosome  cytosol  transcription, DNA-templated  retromer complex  Arp2/3 complex-mediated actin nucleation  retrograde transport, endosome to Golgi  regulation of circadian rhythm  negative regulation of transcription, DNA-templated  rhythmic process  positive regulation of actin nucleation  protein K63-linked ubiquitination  
Ontology : EGO-EBIubiquitin-protein transferase activity  protein binding  nucleus  endosome  early endosome  cytosol  transcription, DNA-templated  retromer complex  Arp2/3 complex-mediated actin nucleation  retrograde transport, endosome to Golgi  regulation of circadian rhythm  negative regulation of transcription, DNA-templated  rhythmic process  positive regulation of actin nucleation  protein K63-linked ubiquitination  
NDEx NetworkMAGEL2
Atlas of Cancer Signalling NetworkMAGEL2
Wikipedia pathwaysMAGEL2
Orthology - Evolution
OrthoDB54551
GeneTree (enSembl)ENSG00000254585
Phylogenetic Trees/Animal Genes : TreeFamMAGEL2
HOVERGENQ9UJ55
HOGENOMQ9UJ55
Homologs : HomoloGeneMAGEL2
Homology/Alignments : Family Browser (UCSC)MAGEL2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMAGEL2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MAGEL2
dbVarMAGEL2
ClinVarMAGEL2
1000_GenomesMAGEL2 
Exome Variant ServerMAGEL2
ExAC (Exome Aggregation Consortium)MAGEL2 (select the gene name)
Genetic variants : HAPMAP54551
Genomic Variants (DGV)MAGEL2 [DGVbeta]
DECIPHERMAGEL2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMAGEL2 
Mutations
ICGC Data PortalMAGEL2 
TCGA Data PortalMAGEL2 
Broad Tumor PortalMAGEL2
OASIS PortalMAGEL2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMAGEL2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMAGEL2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MAGEL2
DgiDB (Drug Gene Interaction Database)MAGEL2
DoCM (Curated mutations)MAGEL2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MAGEL2 (select a term)
intoGenMAGEL2
Cancer3DMAGEL2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM176270    605283    615547   
Orphanet17992    17993    17995    22720    13771   
MedgenMAGEL2
Genetic Testing Registry MAGEL2
NextProtQ9UJ55 [Medical]
TSGene54551
GENETestsMAGEL2
Target ValidationMAGEL2
Huge Navigator MAGEL2 [HugePedia]
snp3D : Map Gene to Disease54551
BioCentury BCIQMAGEL2
ClinGenMAGEL2 (curated)
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54551
Chemical/Pharm GKB GenePA30562
Clinical trialMAGEL2
Miscellaneous
canSAR (ICR)MAGEL2 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMAGEL2
EVEXMAGEL2
GoPubMedMAGEL2
iHOPMAGEL2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:42:03 CEST 2017

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