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MAK (male germ cell-associated kinase)

Identity

Other namesRP62
dJ417M14.2
HGNC (Hugo) MAK
LocusID (NCBI) 4117
Location 6p24.2
Location_base_pair Starts at 10762956 and ends at 10838788 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MAK   6816
Entrez_Gene (NCBI)MAK  4117  male germ cell-associated kinase
Cards
GeneCards (Weizmann)MAK
Ensembl (Hinxton)ENSG00000111837 [Gene_View]  chr6:10762956-10838788 [Contig_View]  MAK [Vega]
AceView (NCBI)MAK
Genatlas (Paris)MAK
SOURCE (Stanford)NM_001242385 NM_001242957 NM_005906
Genomic and cartography
GoldenPath (UCSC)MAK  -  6p24.2   chr6:10762956-10838788 -  6p24.2   [Description]    (hg19-Feb_2009)
EnsemblMAK - 6p24.2 [CytoView]
Mapping of homologs : NCBIMAK [Mapview]
OMIM154235   614181   
Gene and transcription
Genbank (Entrez)AB593146 AF505623 AK097831 AK310329 AK314408
RefSeq transcript (SRS)NM_001242385 NM_001242957 NM_005906
RefSeq transcript (Entrez)NM_001242385 NM_001242957 NM_005906
RefSeq genomic (SRS)AC_000138 NC_000006 NC_018917 NG_030040 NT_007592 NW_001838973 NW_004078026
RefSeq genomic (Entrez)AC_000138 NC_000006 NC_018917 NG_030040 NT_007592 NW_001838973 NW_004078026
Consensus coding sequences : CCDS (NCBI)MAK
Cluster EST : UnigeneHs.446125 [ SRS ] Hs.446125 [ NCBI ]
CGAP (NCI)Hs.446125
Alternative Splicing : Fast-db (Paris)GSHG0026302
Alternative Splicing GalleryENSG00000111837
Gene ExpressionMAK [ NCBI-GEO ]   MAK [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP20794 (SRS) P20794 (Uniprot)
NextProtP20794
With graphics : InterProP20794
Splice isoforms : SwissVarP20794(Swissvar)
Domaine pattern : Prosite (SRS)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (SRS)Kinase-like_dom    Prot_kinase_cat_dom    Protein_kinase_ATP_BS    Ser/Thr_dual-sp_kinase_dom    Ser/Thr_kinase_AS   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_cat_dom    Protein_kinase_ATP_BS    Ser/Thr_dual-sp_kinase_dom    Ser/Thr_kinase_AS   
Related proteins : CluSTrP20794
Domain families : Pfam (SRS)Pkinase (PF00069)   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
DMDM4117
Blocks (Seattle)P20794
Human Protein AtlasENSG00000111837
HPRD01101
IPIIPI00025489   IPI01012634   IPI01011223   
Protein Interaction databases
DIP (DOE-UCLA)P20794
IntAct (EBI)P20794
FunCoupENSG00000111837
REACTOMEMAK
Protein Interaction Database4117
BioGRIDMAK
InParanoidP20794
Interologous Interaction database P20794
IntegromeDBMAK
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)MAK
SNP (GeneSNP Utah)MAK
SNP : HGBaseMAK
Genetic variants : HAPMAPMAK
Somatic Mutations in Cancer : COSMICMAK 
CONAN: Copy Number AnalysisMAK 
Mutations and Diseases : HGMDMAK
OMIM154235    614181   
GENETests154235    614181   
Disease Genetic AssociationMAK
Huge Navigator MAK [HugePedia]  MAK [HugeCancerGEM]
Genomic VariantsMAK  MAK [DGVbeta]
snp3D : Map Gene to Disease4117
General knowledge
Homologs : HomoloGeneMAK
Homology/Alignments : Family Browser (UCSC)MAK
Phylogenetic Trees/Animal Genes : TreeFamMAK
Catalytic activity : Enzyme2.7.11.22 [ Enzyme-Expasy ]   2.7.11.22 [ Enzyme-SRS ]   2.7.11.22 [ IntEnz-EBI ]   2.7.11.22 [ BRENDA ]   2.7.11.22 [ KEGG ]   
Chemical/Protein Interactions : CTD4117
Chemical/Pharm GKB GenePA30564
Clinical trialMAK
Cancer Resource (Charite)ENSG00000111837
Ontology : AmiGOphotoreceptor outer segment  photoreceptor inner segment  transcription coactivator activity  protein kinase activity  cyclin-dependent protein kinase activity  protein binding  ATP binding  nucleus  cytoplasm  centrosome  transcription, DNA-dependent  regulation of transcription, DNA-dependent  protein phosphorylation  protein phosphorylation  multicellular organismal development  spermatogenesis  cell differentiation  midbody  photoreceptor cell maintenance  protein autophosphorylation  mitotic spindle  
Ontology : EGO-EBIphotoreceptor outer segment  photoreceptor inner segment  transcription coactivator activity  protein kinase activity  cyclin-dependent protein kinase activity  protein binding  ATP binding  nucleus  cytoplasm  centrosome  transcription, DNA-dependent  regulation of transcription, DNA-dependent  protein phosphorylation  protein phosphorylation  multicellular organismal development  spermatogenesis  cell differentiation  midbody  photoreceptor cell maintenance  protein autophosphorylation  mitotic spindle  
Other databases
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
PubGeneMAK
iHOPMAK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:46:05 CEST 2013
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