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MAN1C1 (mannosidase alpha class 1C member 1)

Identity

Alias_namesmannosidase, alpha, class 1C, member 1
Alias_symbol (synonym)HMIC
Other aliasMAN1A3
MAN1C
pp6318
HGNC (Hugo) MAN1C1
LocusID (NCBI) 57134
Atlas_Id 68777
Location 1p36.11  [Link to chromosome band 1p36]
Location_base_pair Starts at 25617468 and ends at 25786207 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CNKSR1 (1p36.11) / MAN1C1 (1p36.11)MAN1C1 (1p36.11) / THTPA (14q11.2)RNF145 (5q33.3) / MAN1C1 (1p36.11)
TESK2 (1p34.1) / MAN1C1 (1p36.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MAN1C1   19080
Cards
Entrez_Gene (NCBI)MAN1C1  57134  mannosidase alpha class 1C member 1
AliasesHMIC; MAN1A3; MAN1C; pp6318
GeneCards (Weizmann)MAN1C1
Ensembl hg19 (Hinxton)ENSG00000117643 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000117643 [Gene_View]  chr1:25617468-25786207 [Contig_View]  MAN1C1 [Vega]
ICGC DataPortalENSG00000117643
TCGA cBioPortalMAN1C1
AceView (NCBI)MAN1C1
Genatlas (Paris)MAN1C1
WikiGenes57134
SOURCE (Princeton)MAN1C1
Genetics Home Reference (NIH)MAN1C1
Genomic and cartography
GoldenPath hg38 (UCSC)MAN1C1  -     chr1:25617468-25786207 +  1p36.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MAN1C1  -     1p36.11   [Description]    (hg19-Feb_2009)
EnsemblMAN1C1 - 1p36.11 [CytoView hg19]  MAN1C1 - 1p36.11 [CytoView hg38]
Mapping of homologs : NCBIMAN1C1 [Mapview hg19]  MAN1C1 [Mapview hg38]
OMIM616772   
Gene and transcription
Genbank (Entrez)AB209275 AF261655 AK128560 AL049274 BC038959
RefSeq transcript (Entrez)NM_001289010 NM_020379
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MAN1C1
Cluster EST : UnigeneHs.197043 [ NCBI ]
CGAP (NCI)Hs.197043
Alternative Splicing GalleryENSG00000117643
Gene ExpressionMAN1C1 [ NCBI-GEO ]   MAN1C1 [ EBI - ARRAY_EXPRESS ]   MAN1C1 [ SEEK ]   MAN1C1 [ MEM ]
Gene Expression Viewer (FireBrowse)MAN1C1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57134
GTEX Portal (Tissue expression)MAN1C1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NR34   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NR34  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NR34
Splice isoforms : SwissVarQ9NR34
PhosPhoSitePlusQ9NR34
Domains : Interpro (EBI)Glyco_hydro_47   
Domain families : Pfam (Sanger)Glyco_hydro_47 (PF01532)   
Domain families : Pfam (NCBI)pfam01532   
Conserved Domain (NCBI)MAN1C1
DMDM Disease mutations57134
Blocks (Seattle)MAN1C1
SuperfamilyQ9NR34
Human Protein AtlasENSG00000117643
Peptide AtlasQ9NR34
HPRD14354
IPIIPI00745251   IPI00746125   IPI00103828   IPI00641480   
Protein Interaction databases
DIP (DOE-UCLA)Q9NR34
IntAct (EBI)Q9NR34
FunCoupENSG00000117643
BioGRIDMAN1C1
STRING (EMBL)MAN1C1
ZODIACMAN1C1
Ontologies - Pathways
QuickGOQ9NR34
Ontology : AmiGOGolgi membrane  mannosyl-oligosaccharide 1,2-alpha-mannosidase activity  calcium ion binding  endoplasmic reticulum  protein N-linked glycosylation  N-glycan processing  integral component of Golgi membrane  extracellular exosome  Golgi apparatus mannose trimming  
Ontology : EGO-EBIGolgi membrane  mannosyl-oligosaccharide 1,2-alpha-mannosidase activity  calcium ion binding  endoplasmic reticulum  protein N-linked glycosylation  N-glycan processing  integral component of Golgi membrane  extracellular exosome  Golgi apparatus mannose trimming  
Pathways : BIOCARTASteps in the Glycosylation of Mammalian N-linked Oligosaccarides [Genes]    ER?associated degradation (ERAD) Pathway [Genes]   
Pathways : KEGGN-Glycan biosynthesis    Protein processing in endoplasmic reticulum   
NDEx NetworkMAN1C1
Atlas of Cancer Signalling NetworkMAN1C1
Wikipedia pathwaysMAN1C1
Orthology - Evolution
OrthoDB57134
GeneTree (enSembl)ENSG00000117643
Phylogenetic Trees/Animal Genes : TreeFamMAN1C1
HOVERGENQ9NR34
HOGENOMQ9NR34
Homologs : HomoloGeneMAN1C1
Homology/Alignments : Family Browser (UCSC)MAN1C1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMAN1C1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MAN1C1
dbVarMAN1C1
ClinVarMAN1C1
1000_GenomesMAN1C1 
Exome Variant ServerMAN1C1
ExAC (Exome Aggregation Consortium)MAN1C1 (select the gene name)
Genetic variants : HAPMAP57134
Genomic Variants (DGV)MAN1C1 [DGVbeta]
DECIPHERMAN1C1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMAN1C1 
Mutations
ICGC Data PortalMAN1C1 
TCGA Data PortalMAN1C1 
Broad Tumor PortalMAN1C1
OASIS PortalMAN1C1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMAN1C1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMAN1C1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MAN1C1
DgiDB (Drug Gene Interaction Database)MAN1C1
DoCM (Curated mutations)MAN1C1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MAN1C1 (select a term)
intoGenMAN1C1
Cancer3DMAN1C1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616772   
Orphanet
MedgenMAN1C1
Genetic Testing Registry MAN1C1
NextProtQ9NR34 [Medical]
TSGene57134
GENETestsMAN1C1
Huge Navigator MAN1C1 [HugePedia]
snp3D : Map Gene to Disease57134
BioCentury BCIQMAN1C1
ClinGenMAN1C1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57134
Chemical/Pharm GKB GenePA38788
Clinical trialMAN1C1
Miscellaneous
canSAR (ICR)MAN1C1 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMAN1C1
EVEXMAN1C1
GoPubMedMAN1C1
iHOPMAN1C1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 11:37:47 CEST 2017

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