Identity
HGNC
LOCATION
15q24.2
LOCUSID
ALIAS
MAN6A8,MANA,MANA1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4123
MIM: 154580
HGNC: 6827
Ensembl: ENSG00000140400
Variants:
dbSNP: 4123
ClinVar: 4123
TCGA: ENSG00000140400
COSMIC: MAN2C1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35045343 | 2022 | Impaired catabolism of free oligosaccharides due to MAN2C1 variants causes a neurodevelopmental disorder. | 4 |
| 35045343 | 2022 | Impaired catabolism of free oligosaccharides due to MAN2C1 variants causes a neurodevelopmental disorder. | 4 |
| 27355585 | 2016 | Ancient Haplotypes at the 15q24.2 Microdeletion Region Are Linked to Brain Expression of MAN2C1 and Children's Intelligence. | 2 |
| 27355585 | 2016 | Ancient Haplotypes at the 15q24.2 Microdeletion Region Are Linked to Brain Expression of MAN2C1 and Children's Intelligence. | 2 |
| 23486476 | 2013 | Dual functions for cytosolic α-mannosidase (Man2C1): its down-regulation causes mitochondria-dependent apoptosis independently of its α-mannosidase activity. | 15 |
| 23486476 | 2013 | Dual functions for cytosolic α-mannosidase (Man2C1): its down-regulation causes mitochondria-dependent apoptosis independently of its α-mannosidase activity. | 15 |
| 20978011 | 2011 | Overexpression of Man2C1 leads to protein underglycosylation and upregulation of endoplasmic reticulum-associated degradation pathway. | 11 |
| 21508515 | 2011 | Gene expression and methylation signatures of MAN2C1 are associated with PTSD. | 39 |
| 21556061 | 2011 | α-Mannosidase 2C1 attenuates PTEN function in prostate cancer cells. | 34 |
| 20978011 | 2011 | Overexpression of Man2C1 leads to protein underglycosylation and upregulation of endoplasmic reticulum-associated degradation pathway. | 11 |
| 21508515 | 2011 | Gene expression and methylation signatures of MAN2C1 are associated with PTSD. | 39 |
| 21556061 | 2011 | α-Mannosidase 2C1 attenuates PTEN function in prostate cancer cells. | 34 |
| 19572206 | 2010 | hMan2c1 transgene promotes tumor progress in mice. | 6 |
| 19572206 | 2010 | hMan2c1 transgene promotes tumor progress in mice. | 6 |
| 19018777 | 2008 | Inhibition of alpha-mannosidase Man2c1 gene expression suppresses growth of esophageal carcinoma cells through mitotic arrest and apoptosis. | 7 |
Citation
Dessen P
MAN2C1 (mannosidase alpha class 2C member 1)
Atlas Genet Cytogenet Oncol Haematol. 2009-01-01
Online version: http://atlasgeneticsoncology.org/gene/50614/man2c1
