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MANBA (mannosidase, beta A, lysosomal)

Identity

Other namesMANB1
HGNC (Hugo) MANBA
LocusID (NCBI) 4126
Location 4q24
Location_base_pair Starts at 103552643 and ends at 103682151 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MANBA   6831
Cards
Entrez_Gene (NCBI)MANBA  4126  mannosidase, beta A, lysosomal
GeneCards (Weizmann)MANBA
Ensembl (Hinxton)ENSG00000109323 [Gene_View]  chr4:103552643-103682151 [Contig_View]  MANBA [Vega]
AceView (NCBI)MANBA
Genatlas (Paris)MANBA
WikiGenes4126
SOURCE (Princeton)NM_005908
Genomic and cartography
GoldenPath (UCSC)MANBA  -  4q24   chr4:103552643-103682151 -  4q24   [Description]    (hg19-Feb_2009)
EnsemblMANBA - 4q24 [CytoView]
Mapping of homologs : NCBIMANBA [Mapview]
OMIM248510   609489   
Gene and transcription
Genbank (Entrez)AB209846 AI079197 AK291598 AK300015 AK312827
RefSeq transcript (Entrez)NM_005908
RefSeq genomic (Entrez)AC_000136 NC_000004 NC_018915 NG_012804 NT_016354 NW_001838915 NW_004929320
Consensus coding sequences : CCDS (NCBI)MANBA
Cluster EST : UnigeneHs.480415 [ NCBI ]
CGAP (NCI)Hs.480415
Alternative Splicing : Fast-db (Paris)GSHG0023442
Alternative Splicing GalleryENSG00000109323
Gene ExpressionMANBA [ NCBI-GEO ]     MANBA [ SEEK ]   MANBA [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00462 (Uniprot)
NextProtO00462  [Medical]
With graphics : InterProO00462
Splice isoforms : SwissVarO00462 (Swissvar)
Catalytic activity : Enzyme3.2.1.25 [ Enzyme-Expasy ]   3.2.1.253.2.1.25 [ IntEnz-EBI ]   3.2.1.25 [ BRENDA ]   3.2.1.25 [ KEGG ]   
Domains : Interpro (EBI)Galactose-bd-like    Glyco_hydro_2/20_Ig-like    Glyco_hydro_2_Ig-like    Glyco_hydro_2_N    Glyco_hydro_2_TIM    Glyco_hydro_catalytic_dom    Glycoside_hydrolase_SF   
Related proteins : CluSTrO00462
Domain families : Pfam (Sanger)Glyco_hydro_2_C (PF02836)    Glyco_hydro_2_N (PF02837)   
Domain families : Pfam (NCBI)pfam02836    pfam02837   
DMDM Disease mutations4126
Blocks (Seattle)O00462
Human Protein AtlasENSG00000109323
Peptide AtlasO00462
HPRD02008
IPIIPI00298793   IPI00965393   IPI00965173   
Protein Interaction databases
DIP (DOE-UCLA)O00462
IntAct (EBI)O00462
FunCoupENSG00000109323
BioGRIDMANBA
InParanoidO00462
Interologous Interaction database O00462
IntegromeDBMANBA
STRING (EMBL)MANBA
Ontologies - Pathways
Ontology : AmiGObeta-mannosidase activity  mannose binding  lysosome  cellular protein modification process  glycoprotein catabolic process  mannan catabolic process  
Ontology : EGO-EBIbeta-mannosidase activity  mannose binding  lysosome  cellular protein modification process  glycoprotein catabolic process  mannan catabolic process  
Pathways : KEGGOther glycan degradation    Lysosome   
REACTOMEMANBA
Protein Interaction DatabaseMANBA
Wikipedia pathwaysMANBA
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)MANBA
SNP (GeneSNP Utah)MANBA
SNP : HGBaseMANBA
Genetic variants : HAPMAPMANBA
1000_GenomesMANBA 
ICGC programENSG00000109323 
Somatic Mutations in Cancer : COSMICMANBA 
CONAN: Copy Number AnalysisMANBA 
Mutations and Diseases : HGMDMANBA
OMIM248510    609489   
GENETestsMANBA
Disease Genetic AssociationMANBA
Huge Navigator MANBA [HugePedia]  MANBA [HugeCancerGEM]
Genomic VariantsMANBA  MANBA [DGVbeta]
Exome VariantMANBA
dbVarMANBA
ClinVarMANBA
snp3D : Map Gene to Disease4126
General knowledge
Homologs : HomoloGeneMANBA
Homology/Alignments : Family Browser (UCSC)MANBA
Phylogenetic Trees/Animal Genes : TreeFamMANBA
Chemical/Protein Interactions : CTD4126
Chemical/Pharm GKB GenePA30577
Clinical trialMANBA
Cancer Resource (Charite)ENSG00000109323
Other databases
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
CoreMineMANBA
iHOPMANBA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Apr 18 16:56:30 CEST 2014

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