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MAOA (monoamine oxidase A)

Identity

Alias (NCBI)BRNRS
MAO-A
HGNC (Hugo) MAOA
LocusID (NCBI) 4128
Atlas_Id 51747
Location Xp11.3  [Link to chromosome band Xp11]
Location_base_pair Starts at 43654907 and ends at 43746824 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MAOA (Xp11.3) / ACTB (7p22.1)MAOA (Xp11.3) / MAOA (Xp11.3)MAOA (Xp11.3) / ZFPM1 (16q24.2)
OPHN1 (Xq12) / MAOA (Xp11.3)SPTLC3 (20p12.1) / MAOA (Xp11.3)OPHN1 Xq12 / MAOA Xp11.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)MAOA   6833
Cards
Entrez_Gene (NCBI)MAOA    monoamine oxidase A
AliasesBRNRS; MAO-A
GeneCards (Weizmann)MAOA
Ensembl hg19 (Hinxton)ENSG00000189221 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000189221 [Gene_View]  ENSG00000189221 [Sequence]  chrX:43654907-43746824 [Contig_View]  MAOA [Vega]
ICGC DataPortalENSG00000189221
TCGA cBioPortalMAOA
AceView (NCBI)MAOA
Genatlas (Paris)MAOA
SOURCE (Princeton)MAOA
Genetics Home Reference (NIH)MAOA
Genomic and cartography
GoldenPath hg38 (UCSC)MAOA  -     chrX:43654907-43746824 +  Xp11.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MAOA  -     Xp11.3   [Description]    (hg19-Feb_2009)
GoldenPathMAOA - Xp11.3 [CytoView hg19]  MAOA - Xp11.3 [CytoView hg38]
ImmunoBaseENSG00000189221
Genome Data Viewer NCBIMAOA [Mapview hg19]  
OMIM300615   309850   
Gene and transcription
Genbank (Entrez)AK223499 AK291769 AK293926 BC008064 BC044787
RefSeq transcript (Entrez)NM_000240 NM_001270458
Consensus coding sequences : CCDS (NCBI)MAOA
Gene ExpressionMAOA [ NCBI-GEO ]   MAOA [ EBI - ARRAY_EXPRESS ]   MAOA [ SEEK ]   MAOA [ MEM ]
Gene Expression Viewer (FireBrowse)MAOA [ Firebrowse - Broad ]
GenevisibleExpression of MAOA in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4128
GTEX Portal (Tissue expression)MAOA
Human Protein AtlasENSG00000189221-MAOA [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP21397   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP21397  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP21397
Catalytic activity : Enzyme1.4.3.4 [ Enzyme-Expasy ]   1.4.3.41.4.3.4 [ IntEnz-EBI ]   1.4.3.4 [ BRENDA ]   1.4.3.4 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusP21397
Domains : Interpro (EBI)Amino_oxidase    FAD/NAD-bd_sf    Flavin_amine_oxidase   
Domain families : Pfam (Sanger)Amino_oxidase (PF01593)   
Domain families : Pfam (NCBI)pfam01593   
Conserved Domain (NCBI)MAOA
PDB (RSDB)1H8Q    2BXR    2BXS    2Z5X    2Z5Y   
PDB Europe1H8Q    2BXR    2BXS    2Z5X    2Z5Y   
PDB (PDBSum)1H8Q    2BXR    2BXS    2Z5X    2Z5Y   
PDB (IMB)1H8Q    2BXR    2BXS    2Z5X    2Z5Y   
Structural Biology KnowledgeBase1H8Q    2BXR    2BXS    2Z5X    2Z5Y   
SCOP (Structural Classification of Proteins)1H8Q    2BXR    2BXS    2Z5X    2Z5Y   
CATH (Classification of proteins structures)1H8Q    2BXR    2BXS    2Z5X    2Z5Y   
SuperfamilyP21397
AlphaFold pdb e-kbP21397   
Human Protein Atlas [tissue]ENSG00000189221-MAOA [tissue]
HPRD02400
Protein Interaction databases
DIP (DOE-UCLA)P21397
IntAct (EBI)P21397
BioGRIDMAOA
STRING (EMBL)MAOA
ZODIACMAOA
Ontologies - Pathways
QuickGOP21397
Ontology : AmiGOprotein binding  mitochondrion  mitochondrion  mitochondrial outer membrane  cytosol  cellular biogenic amine metabolic process  xenobiotic metabolic process  primary amine oxidase activity  positive regulation of signal transduction  integral component of membrane  cytokine-mediated signaling pathway  neurotransmitter metabolic process  neurotransmitter catabolic process  dopamine catabolic process  monoamine oxidase activity  
Ontology : EGO-EBIprotein binding  mitochondrion  mitochondrion  mitochondrial outer membrane  cytosol  cellular biogenic amine metabolic process  xenobiotic metabolic process  primary amine oxidase activity  positive regulation of signal transduction  integral component of membrane  cytokine-mediated signaling pathway  neurotransmitter metabolic process  neurotransmitter catabolic process  dopamine catabolic process  monoamine oxidase activity  
Pathways : KEGGGlycine, serine and threonine metabolism    Arginine and proline metabolism    Histidine metabolism    Tyrosine metabolism    Phenylalanine metabolism    Tryptophan metabolism    Drug metabolism - cytochrome P450    Serotonergic synapse    Dopaminergic synapse    Cocaine addiction    Amphetamine addiction    Alcoholism   
NDEx NetworkMAOA
Atlas of Cancer Signalling NetworkMAOA
Wikipedia pathwaysMAOA
Orthology - Evolution
OrthoDB4128
GeneTree (enSembl)ENSG00000189221
Phylogenetic Trees/Animal Genes : TreeFamMAOA
Homologs : HomoloGeneMAOA
Homology/Alignments : Family Browser (UCSC)MAOA
Gene fusions - Rearrangements
Fusion : MitelmanOPHN1/MAOA [Xq12/Xp11.3]  
Fusion : MitelmanSPTLC3/MAOA [20p12.1/Xp11.3]  
Fusion : QuiverMAOA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMAOA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MAOA
dbVarMAOA
ClinVarMAOA
MonarchMAOA
1000_GenomesMAOA 
Exome Variant ServerMAOA
GNOMAD BrowserENSG00000189221
Varsome BrowserMAOA
ACMGMAOA variants
VarityP21397
Genomic Variants (DGV)MAOA [DGVbeta]
DECIPHERMAOA [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMAOA 
Mutations
ICGC Data PortalMAOA 
TCGA Data PortalMAOA 
Broad Tumor PortalMAOA
OASIS PortalMAOA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMAOA  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMAOA
Mutations and Diseases : HGMDMAOA
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMAOA
DgiDB (Drug Gene Interaction Database)MAOA
DoCM (Curated mutations)MAOA
CIViC (Clinical Interpretations of Variants in Cancer)MAOA
Cancer3DMAOA
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300615    309850   
Orphanet2747   
DisGeNETMAOA
MedgenMAOA
Genetic Testing Registry MAOA
NextProtP21397 [Medical]
GENETestsMAOA
Target ValidationMAOA
Huge Navigator MAOA [HugePedia]
ClinGenMAOA (curated)
Clinical trials, drugs, therapy
MyCancerGenomeMAOA
Protein Interactions : CTDMAOA
Pharm GKB GenePA236
Pharm GKB PathwaysPA161749006   
PharosP21397
Clinical trialMAOA
Miscellaneous
canSAR (ICR)MAOA
HarmonizomeMAOA
DataMed IndexMAOA
Probes
Litterature
PubMed499 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMAOA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:17:38 CEST 2021

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