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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome

Donate (in Euros)

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MAOA (monoamine oxidase A)

Identity

Other namesMAO-A
HGNC (Hugo) MAOA
LocusID (NCBI) 4128
Location Xp11.3
Location_base_pair Starts at 43514155 and ends at 43606071 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

Other Solid tumors implicated (Data extracted from papers in the Atlas)

Solid Tumors AmeloblastomID5945

External links

Nomenclature
HGNC (Hugo)MAOA   6833
Cards
Entrez_Gene (NCBI)MAOA  4128  monoamine oxidase A
GeneCards (Weizmann)MAOA
Ensembl hg19 (Hinxton) [Gene_View]  chrX:43514155-43606071 [Contig_View]  MAOA [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chrX:43514155-43606071 [Contig_View]  MAOA [Vega]
cBioPortalMAOA
AceView (NCBI)MAOA
Genatlas (Paris)MAOA
WikiGenes4128
SOURCE (Princeton)MAOA
Genomic and cartography
GoldenPath hg19 (UCSC)MAOA  -     chrX:43514155-43606071 +  Xp11.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MAOA  -     Xp11.3   [Description]    (hg38-Dec_2013)
EnsemblMAOA - Xp11.3 [CytoView hg19]  MAOA - Xp11.3 [CytoView hg38]
Mapping of homologs : NCBIMAOA [Mapview hg19]  MAOA [Mapview hg38]
OMIM300615   309850   
Gene and transcription
Genbank (Entrez)AK223499 AK291769 AK293926 BC008064 BC044787
RefSeq transcript (Entrez)NM_000240 NM_001270458
RefSeq genomic (Entrez)AC_000155 NC_000023 NC_018934 NG_008957 NT_079573 NW_001842361 NW_004929439
Consensus coding sequences : CCDS (NCBI)MAOA
Cluster EST : UnigeneHs.183109 [ NCBI ]
CGAP (NCI)Hs.183109
Alternative Splicing : Fast-db (Paris)GSHG0031474
Gene ExpressionMAOA [ NCBI-GEO ]     MAOA [ SEEK ]   MAOA [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP21397 (Uniprot)
NextProtP21397  [Medical]
With graphics : InterProP21397
Splice isoforms : SwissVarP21397 (Swissvar)
Catalytic activity : Enzyme1.4.3.4 [ Enzyme-Expasy ]   1.4.3.41.4.3.4 [ IntEnz-EBI ]   1.4.3.4 [ BRENDA ]   1.4.3.4 [ KEGG ]   
Domains : Interpro (EBI)Amino_oxidase    Flavin_amine_oxidase   
Related proteins : CluSTrP21397
Domain families : Pfam (Sanger)Amino_oxidase (PF01593)   
Domain families : Pfam (NCBI)pfam01593   
DMDM Disease mutations4128
Blocks (Seattle)P21397
PDB (SRS)1H8Q    2BXR    2BXS    2Z5X    2Z5Y   
PDB (PDBSum)1H8Q    2BXR    2BXS    2Z5X    2Z5Y   
PDB (IMB)1H8Q    2BXR    2BXS    2Z5X    2Z5Y   
PDB (RSDB)1H8Q    2BXR    2BXS    2Z5X    2Z5Y   
Peptide AtlasP21397
HPRD02400
IPIIPI00008483   IPI00980468   
Protein Interaction databases
DIP (DOE-UCLA)P21397
IntAct (EBI)P21397
BioGRIDMAOA
IntegromeDBMAOA
STRING (EMBL)MAOA
Ontologies - Pathways
QuickGOP21397
Ontology : AmiGOmitochondrion  mitochondrial outer membrane  cellular biogenic amine metabolic process  xenobiotic metabolic process  synaptic transmission  neurotransmitter secretion  primary amine oxidase activity  integral component of membrane  neurotransmitter catabolic process  neurotransmitter biosynthetic process  dopamine catabolic process  small molecule metabolic process  oxidation-reduction process  
Ontology : EGO-EBImitochondrion  mitochondrial outer membrane  cellular biogenic amine metabolic process  xenobiotic metabolic process  synaptic transmission  neurotransmitter secretion  primary amine oxidase activity  integral component of membrane  neurotransmitter catabolic process  neurotransmitter biosynthetic process  dopamine catabolic process  small molecule metabolic process  oxidation-reduction process  
Pathways : KEGGGlycine, serine and threonine metabolism    Arginine and proline metabolism    Histidine metabolism    Tyrosine metabolism    Phenylalanine metabolism    Tryptophan metabolism    Drug metabolism - cytochrome P450    Serotonergic synapse    Dopaminergic synapse    Cocaine addiction    Amphetamine addiction    Alcoholism   
Protein Interaction DatabaseMAOA
DoCM (Curated mutations)MAOA
Wikipedia pathwaysMAOA
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerMAOA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MAOA
dbVarMAOA
ClinVarMAOA
1000_GenomesMAOA 
Exome Variant ServerMAOA
SNP (GeneSNP Utah)MAOA
SNP : HGBaseMAOA
Genetic variants : HAPMAPMAOA
Genomic Variants (DGV)MAOA [DGVbeta]
Mutations
Somatic Mutations in Cancer : COSMICMAOA 
CONAN: Copy Number AnalysisMAOA 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)X:43514155-43606071
Mutations and Diseases : HGMDMAOA
OMIM300615    309850   
MedgenMAOA
NextProtP21397 [Medical]
GENETestsMAOA
Disease Genetic AssociationMAOA
Huge Navigator MAOA [HugePedia]  MAOA [HugeCancerGEM]
snp3D : Map Gene to Disease4128
DGIdb (Drug Gene Interaction db)MAOA
General knowledge
Homologs : HomoloGeneMAOA
Homology/Alignments : Family Browser (UCSC)MAOA
Phylogenetic Trees/Animal Genes : TreeFamMAOA
Chemical/Protein Interactions : CTD4128
Chemical/Pharm GKB GenePA236
Clinical trialMAOA
Other databases
Probes
Litterature
PubMed435 Pubmed reference(s) in Entrez
CoreMineMAOA
GoPubMedMAOA
iHOPMAOA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 14 17:28:29 CET 2015

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jlhuret@AtlasGeneticsOncology.org.