Identity
HGNC
LOCATION
20q11.22
LOCUSID
ALIAS
ATG8E,LC3,LC3A,MAP1ALC3,MAP1BLC3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84557
MIM: 601242
HGNC: 6838
Ensembl: ENSG00000101460
Variants:
dbSNP: 84557
ClinVar: 84557
TCGA: ENSG00000101460
COSMIC: MAP1LC3A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000101460 | ENST00000360668 | Q9H492 |
| ENSG00000101460 | ENST00000374837 | Q9H492 |
| ENSG00000101460 | ENST00000397709 | Q9H492 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38953845 | 2024 | The Role of LC3-Associated Phagocytosis Inhibits the Inflammatory Response in Aspergillus fumigatus Keratitis. | 0 |
| 38953845 | 2024 | The Role of LC3-Associated Phagocytosis Inhibits the Inflammatory Response in Aspergillus fumigatus Keratitis. | 0 |
| 36675134 | 2023 | Cytoplasmic Expression of TP53INP2 Modulated by Demethylase FTO and Mutant NPM1 Promotes Autophagy in Leukemia Cells. | 8 |
| 36766737 | 2023 | Mitophagy Effects of Protodioscin on Human Osteosarcoma Cells by Inhibition of p38MAPK Targeting NIX/LC3 Axis. | 2 |
| 37948986 | 2023 | Synovial fluid exosome-derived miR-182-5p alleviates osteoarthritis by downregulating TNFAIP8 and promoting autophagy through LC3 signaling. | 1 |
| 36675134 | 2023 | Cytoplasmic Expression of TP53INP2 Modulated by Demethylase FTO and Mutant NPM1 Promotes Autophagy in Leukemia Cells. | 8 |
| 36766737 | 2023 | Mitophagy Effects of Protodioscin on Human Osteosarcoma Cells by Inhibition of p38MAPK Targeting NIX/LC3 Axis. | 2 |
| 37948986 | 2023 | Synovial fluid exosome-derived miR-182-5p alleviates osteoarthritis by downregulating TNFAIP8 and promoting autophagy through LC3 signaling. | 1 |
| 34689707 | 2022 | Human platelets display dysregulated sepsis-associated autophagy, induced by altered LC3 protein-protein interaction of the Vici-protein EPG5. | 5 |
| 34974132 | 2022 | LC3 and NLRC5 interaction inhibits NLRC5-mediated MHC class I antigen presentation pathway in endometrial cancer. | 14 |
| 34978373 | 2022 | Synthesis of 20-Membered Macrocyclic Pseudo-Natural Products Yields Inducers of LC3 Lipidation. | 4 |
| 35008961 | 2022 | LC3/FtMt Colocalization Patterns Reveal the Progression of FtMt Accumulation in Nigral Neurons of Patients with Progressive Supranuclear Palsy. | 1 |
| 35057513 | 2022 | Intracellular Toxic Advanced Glycation End-Products in 1.4E7 Cell Line Induce Death with Reduction of Microtubule-Associated Protein 1 Light Chain 3 and p62. | 11 |
| 35163014 | 2022 | Role of Organic Cation Transporter 2 in Autophagy Induced by Platinum Derivatives. | 1 |
| 35310852 | 2022 | Recruitment of LC3 by Campylobacter jejuni to Bacterial Invasion Site on Host Cells via the Rac1-Mediated Signaling Pathway. | 3 |
Citation
Dessen P
MAP1LC3A (microtubule associated protein 1 light chain 3 alpha)
Atlas Genet Cytogenet Oncol Haematol. 2009-01-01
Online version: http://atlasgeneticsoncology.org/gene/50647/map1lc3a
