MAP1LC3C (microtubule associated protein 1 light chain 3 gamma)

2015-02-01  

Identity

HGNC
LOCATION
1q43
LOCUSID
ALIAS
ATG8J,LC3C

Other Information

Locus ID:

NCBI: 440738
MIM: 609605
HGNC: 13353
Ensembl: ENSG00000197769

Variants:

dbSNP: 440738
ClinVar: 440738
TCGA: ENSG00000197769
COSMIC: MAP1LC3C

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197769ENST00000357246Q9BXW4

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Cellular responses to stressREACTOMER-HSA-2262752
MacroautophagyREACTOMER-HSA-1632852
FerroptosisKEGGko04216
FerroptosisKEGGhsa04216

References

Pubmed IDYearTitleCitations
230223822012LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy.109
264310262015TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER Export.36
243004352014Autophagy suppresses melanoma tumorigenesis by inducing senescence.23
278808992016LC3C Contributes to Vpu-Mediated Antagonism of BST2/Tetherin Restriction on HIV-1 Release through a Non-canonical Autophagy Pathway.13
284046432017The BEACH-containing protein WDR81 coordinates p62 and LC3C to promote aggrephagy.13
291495992017Autophagosomal Content Profiling Reveals an LC3C-Dependent Piecemeal Mitophagy Pathway.0

Citation

Dessen P

MAP1LC3C (microtubule associated protein 1 light chain 3 gamma)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/54959/map1lc3c