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MAP7 (microtubule associated protein 7)

Identity

Alias_symbol (synonym)E-MAP-115
Other aliasEMAP115
HGNC (Hugo) MAP7
LocusID (NCBI) 9053
Atlas_Id 50426
Location 6q23.3  [Link to chromosome band 6q23]
Location_base_pair Starts at 136342281 and ends at 136550819 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BCLAF1 (6q23.3) / MAP7 (6q23.3)MAP7 (6q23.3) / ARG1 (6q23.2)MAP7 (6q23.3) / CNKSR3 (6q25.2)
MAP7 (6q23.3) / ECHDC1 (6q22.33)MAP7 (6q23.3) / GATAD2B (1q21.3)MAP7 (6q23.3) / MAP3K5 (6q23.3)
MAP7 (6q23.3) / MAP7 (6q23.3)MAP7 (6q23.3) / ZBTB20 (3q13.31)STAR (8p11.23) / MAP7 (6q23.3)
BCLAF1 6q23.3 / MAP7 6q23.3MAP7 6q23.3 / ARG1 6q23.2MAP7 6q23.3 / CNKSR3 6q25.2
MAP7 6q23.3 / ECHDC1 6q22.33MAP7 6q23.3 / MAP3K5 6q23.3MAP7 6q23.3 / ZBTB20 3q13.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 9 ]
  t(3;6)(q13;q23) MAP7/ZBTB20
t(6;6)(q22;q23) MAP7/ECHDC1
t(6;6)(q22;q23) MAP7/TPD52L1
BCLAF1/MAP7 (6q23)
MAP7/AHI1 (6q23)
MAP7/ARG1 (6q23)
MAP7/MAP3K5 (6q23)
t(6;6)(q23;q25) MAP7/AKAP12
t(6;6)(q23;q25) MAP7/CNKSR3


External links

Nomenclature
HGNC (Hugo)MAP7   6869
Cards
Entrez_Gene (NCBI)MAP7  9053  microtubule associated protein 7
AliasesE-MAP-115; EMAP115
GeneCards (Weizmann)MAP7
Ensembl hg19 (Hinxton)ENSG00000135525 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135525 [Gene_View]  ENSG00000135525 [Sequence]  chr6:136342281-136550819 [Contig_View]  MAP7 [Vega]
ICGC DataPortalENSG00000135525
TCGA cBioPortalMAP7
AceView (NCBI)MAP7
Genatlas (Paris)MAP7
WikiGenes9053
SOURCE (Princeton)MAP7
Genetics Home Reference (NIH)MAP7
Genomic and cartography
GoldenPath hg38 (UCSC)MAP7  -     chr6:136342281-136550819 -  6q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MAP7  -     6q23.3   [Description]    (hg19-Feb_2009)
EnsemblMAP7 - 6q23.3 [CytoView hg19]  MAP7 - 6q23.3 [CytoView hg38]
Mapping of homologs : NCBIMAP7 [Mapview hg19]  MAP7 [Mapview hg38]
OMIM604108   
Gene and transcription
Genbank (Entrez)AB073649 AI344295 AJ242501 AJ242502 AJ420541
RefSeq transcript (Entrez)NM_001198608 NM_001198609 NM_001198611 NM_001198614 NM_001198615 NM_001198616 NM_001198617 NM_001198618 NM_001198619 NM_003980
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MAP7
Cluster EST : UnigeneHs.486548 [ NCBI ]
CGAP (NCI)Hs.486548
Alternative Splicing GalleryENSG00000135525
Gene ExpressionMAP7 [ NCBI-GEO ]   MAP7 [ EBI - ARRAY_EXPRESS ]   MAP7 [ SEEK ]   MAP7 [ MEM ]
Gene Expression Viewer (FireBrowse)MAP7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9053
GTEX Portal (Tissue expression)MAP7
Human Protein AtlasENSG00000135525-MAP7 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14244   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14244  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14244
Splice isoforms : SwissVarQ14244
PhosPhoSitePlusQ14244
Domains : Interpro (EBI)MAP7    MAP7_fam   
Domain families : Pfam (Sanger)MAP7 (PF05672)   
Domain families : Pfam (NCBI)pfam05672   
Conserved Domain (NCBI)MAP7
DMDM Disease mutations9053
Blocks (Seattle)MAP7
SuperfamilyQ14244
Human Protein Atlas [tissue]ENSG00000135525-MAP7 [tissue]
Peptide AtlasQ14244
HPRD04982
IPIIPI00939172   IPI00942205   IPI00020771   IPI00976733   IPI00022628   IPI00797162   IPI00985007   IPI00982359   
Protein Interaction databases
DIP (DOE-UCLA)Q14244
IntAct (EBI)Q14244
FunCoupENSG00000135525
BioGRIDMAP7
STRING (EMBL)MAP7
ZODIACMAP7
Ontologies - Pathways
QuickGOQ14244
Ontology : AmiGOmicrotubule cytoskeleton organization  signaling receptor binding  structural molecule activity  protein binding  cytosol  microtubule  microtubule associated complex  response to osmotic stress  establishment or maintenance of cell polarity  microtubule cytoskeleton  microtubule cytoskeleton  basolateral plasma membrane  axon  perinuclear region of cytoplasm  protein localization to plasma membrane  
Ontology : EGO-EBImicrotubule cytoskeleton organization  signaling receptor binding  structural molecule activity  protein binding  cytosol  microtubule  microtubule associated complex  response to osmotic stress  establishment or maintenance of cell polarity  microtubule cytoskeleton  microtubule cytoskeleton  basolateral plasma membrane  axon  perinuclear region of cytoplasm  protein localization to plasma membrane  
NDEx NetworkMAP7
Atlas of Cancer Signalling NetworkMAP7
Wikipedia pathwaysMAP7
Orthology - Evolution
OrthoDB9053
GeneTree (enSembl)ENSG00000135525
Phylogenetic Trees/Animal Genes : TreeFamMAP7
HOVERGENQ14244
HOGENOMQ14244
Homologs : HomoloGeneMAP7
Homology/Alignments : Family Browser (UCSC)MAP7
Gene fusions - Rearrangements
Fusion : MitelmanBCLAF1/MAP7 [6q23.3/6q23.3]  [t(6;6)(q23;q23)]  
Fusion : MitelmanMAP7/ARG1 [6q23.3/6q23.2]  [t(6;6)(q23;q23)]  
Fusion : MitelmanMAP7/CNKSR3 [6q23.3/6q25.2]  [t(6;6)(q23;q25)]  
Fusion : MitelmanMAP7/ECHDC1 [6q23.3/6q22.33]  [t(6;6)(q22;q23)]  
Fusion : MitelmanMAP7/MAP3K5 [6q23.3/6q23.3]  [t(6;6)(q23;q23)]  
Fusion : MitelmanMAP7/ZBTB20 [6q23.3/3q13.31]  [t(3;6)(q13;q23)]  
Fusion PortalBCLAF1 6q23.3 MAP7 6q23.3 BRCA
Fusion PortalMAP7 6q23.3 ARG1 6q23.2 BRCA
Fusion PortalMAP7 6q23.3 CNKSR3 6q25.2 BRCA
Fusion PortalMAP7 6q23.3 ECHDC1 6q22.33 BRCA
Fusion PortalMAP7 6q23.3 MAP3K5 6q23.3 PRAD
Fusion PortalMAP7 6q23.3 ZBTB20 3q13.31 KIRC
Fusion : QuiverMAP7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMAP7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MAP7
dbVarMAP7
ClinVarMAP7
1000_GenomesMAP7 
Exome Variant ServerMAP7
ExAC (Exome Aggregation Consortium)ENSG00000135525
GNOMAD BrowserENSG00000135525
Varsome BrowserMAP7
Genetic variants : HAPMAP9053
Genomic Variants (DGV)MAP7 [DGVbeta]
DECIPHERMAP7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMAP7 
Mutations
ICGC Data PortalMAP7 
TCGA Data PortalMAP7 
Broad Tumor PortalMAP7
OASIS PortalMAP7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMAP7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMAP7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MAP7
DgiDB (Drug Gene Interaction Database)MAP7
DoCM (Curated mutations)MAP7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MAP7 (select a term)
intoGenMAP7
Cancer3DMAP7(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604108   
Orphanet
DisGeNETMAP7
MedgenMAP7
Genetic Testing Registry MAP7
NextProtQ14244 [Medical]
TSGene9053
GENETestsMAP7
Target ValidationMAP7
Huge Navigator MAP7 [HugePedia]
snp3D : Map Gene to Disease9053
BioCentury BCIQMAP7
ClinGenMAP7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9053
Chemical/Pharm GKB GenePA30615
Clinical trialMAP7
Miscellaneous
canSAR (ICR)MAP7 (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMAP7
EVEXMAP7
GoPubMedMAP7
iHOPMAP7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:18:52 CET 2018

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