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MAPK13 (mitogen-activated protein kinase 13)

Written2009-12Maria Isabel Cerezo-Guisado, Ana Cuenda
Centro Nacional de Biotecnologia-CSIC, Department of Immunology, Oncology, Madrid, Spain

(Note : for Links provided by Atlas : click)


Alias (NCBI)MGC99536
HGNC (Hugo) MAPK13
HGNC Alias symbSAPK4
HGNC Previous namePRKM13
LocusID (NCBI) 5603
Atlas_Id 41291
Location 6p21.31  [Link to chromosome band 6p21]
Location_base_pair Starts at 36130513 and ends at 36144521 bp from pter ( according to GRCh38/hg38-Dec_2013)  [Mapping MAPK13.png]
  MAPK13 genomic context (chromosome 6, location 6p21.31).
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)


  Genomic organization of MAPK13 gene on chromosome 6p21.31. The boxes indicate coding regions (exon 1-12) of the gene.
Description The MAPK13 entire gene spans 9.58 Kb on the short arm of chromosome 6. It contains 12 exons.
Transcription The MAPK13 gene encodes a 365 amino-acid protein of about 40 KDa. No splice variants have been reported.
Pseudogene No human or mouse pseudogene known.


Note p38delta (MAPK13), also known as Stress-activated protein kinase 4 (SAPK4) belongs to the p38 subfamily of MAPKs. The p38MAPK subfamily is composed by four members encoded by different genes, which share high sequence homologues and are designated as p38alpha (MAPK14, or SAPK2a), p38beta (MAPK11 or SAPK2b), p38gamma (MAPK12 or SAPK3) and p38delta (MAPK13 or SAPK4). They are about 60% identical in their amino acid sequence but differ in their expression patterns, substrate specificities and sensitivities to chemical inhibitors (Iñesta-Vaquera et al., 2008). All p38 MAPKs are strongly activated in vivo by environmental stresses and inflammatory cytokines, and less by serum and growth factors.
  Schematic representation of the p38delta (MAPK13) protein structure. Kinase Domain, catalytic kinase domain; TGY, sequence motif containing the regulatory phosphorylation residues.
Description p38delta (MAPK13) is a Serine/Threonine protein kinase of 365 amino acids with a predicted molecular mass of 40 kDa. It possesses the conserved amino acid domains (I-XI) characteristic of protein kinases (Goedert et al., 1997). The Thr180 and Tyr182 residues in subdomain VIII are in an equivalent position to the TXY sequence in known MAPKs. The activation of p38delta (MAPK13) occurs via dual phosphorilation of its TGY motif, in the activation loop, by MKK3 and MKK6, although it is preferentially activated by MKK3 in mouse embryonic fibroblasts (Remy et al., 2009).
Expression p38delta (MAPK13) mRNA is widely expressed with high levels of expression in testes, pancreas, kidney and small intestine.
Localisation p38delta (MAPK13) localizes to the cytoplasm and nucleus of cultured cells.
Function p38delta (MAPK13) phosphorylates typical p38 MAPK substrates such as the transcription factors ATF2, Elk-1 or SAP1. However, it cannot phosphorylate MAPKAPK2 or MAPKAPK3, which are good substrates for other p38 MAPK isoforms (Cuenda et al., 1997; Goedert et al., 1997). p38delta possibly plays a role in cytoskeleton regulation as it has been reported to phosphorylate the cytoplasmic protein stathmin, which has been linked to regulation of microtubule dynamics (Parker et al., 1998). Microtubule-associated protein Tau is another protein substrate of p38delta (Goedert et al., 1997; Feijoo et al., 2005; Yoshida and Goedert, 2006). In addition p38delta plays a role in the regulation of protein translation by phosphorylating and inactivating the (Knebel et al., 2001; Knebel et al., 2002). p38delta also plays a key role in the regulation of insulin secretion as well as in the survival of pancreatic beta cells, since p38delta catalyzes an inhibitory phosphorylation of the protein kinase D1 (PDK1), which controls insuline exocytosis in pancreatic beta cells (Sumara et al., 2009). p38delta has been suggested to play an important role in inducing keratinocyte differentiation by regulating the expression of involucrin, which is a protein expressed during keratinocyte differentiation (Eckert et al., 2003). Activation of exogenously expressed p38delta by differentiation-inducing agents such as a bioactive green tea polyphenol (EGCG), okadaic acid (OA) or the phorbol ester TPA, correlated with increased involucrin promoter activity in keratinocytes via increased activity at AP1, Sp1 and C/EBP sites (Balasubramanian et al., 2002; Efimova et al., 2003). The mechanisms by which p38delta may regulates keratinocyte differentiation is still unknown, although it has been reported that in keratinocytes expressing exogenous p38delta this forms a complex with ERK1/ERK2 (Efimova et al., 2003; Eckert et al., 2004). Additional data supporting the idea that p38delta may play a role in keratinocyte differentiation come from a study carried out in lesional psoriasis skin (Johansen et al., 2005). It has been shown that the activity of p38alpha, p38beta and p38delta are augmented in lesional psoriasis skin compared with nonlesional psoriasis skin (Johansen et al., 2005). Alternatively, it has been also claimed that p38delta may have a dual role in keratinocytes contributing not only to the differentiation process, but also to their apoptosis in a PKCdelta dependent manner, and in response to OA or H2O2 (Efimova et al., 2004; Kraft et al., 2007).
Homology p38delta (MAPK13) shows 70% identity with p38gamma (MAPK12), 60% sequence identity with p38alpha (MAPK14) and p38beta (MAPK11), 45% identity with HOG1 from S. cerevisiae, 47% identity with human SAP kinase-1 (JNK1) and 42% identity with p42 MAPkinase (ERK2).

Implicated in

Entity Skin cancer
Oncogenesis It has been suggested that p38delta functions as positive regulator of skin tumorogenesis by promoting cell proliferation and tumor development in epidermis (Schindler et al., 2009).
Entity Cholangiocarcinoma
Oncogenesis p38delta may serve as a diagnostic marker for expression cholangiocarcinoma (CC), since its expression is upregulated in CC relative to hepatocellularcarcinoma (HCC) and to normal biliary tract tissue (Li-Sher et al., 2009). It has been suggested that p38delta is important for motility and invasion of CC cells (Li-Sher et al., 2009).
Entity Malignant Pleural Mesothelioma
Oncogenesis MAPK13 gene is hypermethylated in Malignant Pleural Mesothelioma (MPM) cell lines (Goto et al., 2009).
Entity Alzheimer disease
Note The protein Tau is a good in vitro substrate for the p38 isoforms p38delta and p38gamma, and its phosphorylation by these two enzymes results in a reduction in its ability to promote microtubule assembly (Goedert et al., 1997b; Feijoo et al., 2005). Moreover, overexpression of p38gamma in neuroblastoma, induces Tau phosphorylation which correlates with a decrease on Tau associated to the cytoskeleton and an increase of soluble Tau (Jenkins et al., 2000). It has been reported as well that p38delta is the major Tau kinase in neuroblastoma in response to osmotic shock (Feijoo et al., 2005) and that the p38MAPK activator, MKK6, has also been found to be active in neurodegenerative diseases (Zhu et al., 2001). Moreover, oxidant agents implicated in Alzheimer's disease can cause hyperphosphorylation in rat brain and also induce the activation of p38delta, indicating that this kinase may be involved in Tau phosphorylation (Yin et al., 2006). On the other hand, it has been shown using phosphospecific antibodies that p38MAPKs phosphorylate Tau on residues phosphorylated in a Tau obtained from patients suffering Alzheimer's disease (Goedert et al., 1997b; Feijoo et al., 2005).
Entity Diabetes type 2 (diabetes mellitus)
Note p38delta plays a key role in the regulation of insulin secretion as well as in the survival of pancreatic beta cells (Sumara et al., 2009).


Green tea polyphenol stimulates a Ras, MEKK1, MEK3, and p38 cascade to increase activator protein 1 factor-dependent involucrin gene expression in normal human keratinocytes.
Balasubramanian S, Efimova T, Eckert RL.
J Biol Chem. 2002 Jan 18;277(3):1828-36. Epub 2001 Nov 6.
PMID 11698415
Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38).
Cuenda A, Cohen P, Buee-Scherrer V, Goedert M.
EMBO J. 1997 Jan 15;16(2):295-305.
PMID 9029150
p38 MAP-kinases pathway regulation, function and role in human diseases.
Cuenda A, Rousseau S.
Biochim Biophys Acta. 2007 Aug;1773(8):1358-75. Epub 2007 Mar 24. (REVIEW)
PMID 17481747
Antioxidants regulate normal human keratinocyte differentiation.
Eckert RL, Crish JF, Efimova T, Balasubramanian S.
Biochem Pharmacol. 2004 Sep 15;68(6):1125-31.
PMID 15313409
p38 Mitogen-activated protein kinases on the body surface--a function for p38 delta.
Eckert RL, Efimova T, Balasubramanian S, Crish JF, Bone F, Dashti S.
J Invest Dermatol. 2003 May;120(5):823-8. (REVIEW)
PMID 12713588
Protein kinase Cdelta regulates keratinocyte death and survival by regulating activity and subcellular localization of a p38delta-extracellular signal-regulated kinase 1/2 complex.
Efimova T, Broome AM, Eckert RL.
Mol Cell Biol. 2004 Sep;24(18):8167-83.
PMID 15340077
Evidence that phosphorylation of the microtubule-associated protein Tau by SAPK4/p38delta at Thr50 promotes microtubule assembly.
Feijoo C, Campbell DG, Jakes R, Goedert M, Cuenda A.
J Cell Sci. 2005 Jan 15;118(Pt 2):397-408. Epub 2005 Jan 4.
PMID 15632108
Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases.
Goedert M, Cuenda A, Craxton M, Jakes R, Cohen P.
EMBO J. 1997a Jun 16;16(12):3563-71.
PMID 9218798
Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases.
Goedert M, Hasegawa M, Jakes R, Lawler S, Cuenda A, Cohen P.
FEBS Lett. 1997b Jun 2;409(1):57-62.
PMID 9199504
Epigenetic profiles distinguish malignant pleural mesothelioma from lung adenocarcinoma.
Goto Y, Shinjo K, Kondo Y, Shen L, Toyota M, Suzuki H, Gao W, An B, Fujii M, Murakami H, Osada H, Taniguchi T, Usami N, Kondo M, Hasegawa Y, Shimokata K, Matsuo K, Hida T, Fujimoto N, Kishimoto T, Issa JP, Sekido Y.
Cancer Res. 2009 Dec 1;69(23):9073-82. Epub 2009 Nov 3.
PMID 19887624
Alternative p38MAPK pathways. Stress activated protein kinases.
Inesta-Vaquera F., Sabio G., Kuma Y, Cuenda A
Topics in Current Genetics. Springer-Verlag Berlin Heidelberg (DOI 10-1007/978-3-540-75569-2) 2008; 20:17-26
Modulation of tau phosphorylation and intracellular localization by cellular stress.
Jenkins SM, Zinnerman M, Garner C, Johnson GV.
Biochem J. 2000 Jan 15;345 Pt 2:263-70.
PMID 10620503
The mitogen-activated protein kinases p38 and ERK1/2 are increased in lesional psoriatic skin.
Johansen C, Kragballe K, Westergaard M, Henningsen J, Kristiansen K, Iversen L.
Br J Dermatol. 2005 Jan;152(1):37-42.
PMID 15656798
Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and -insensitive pathways.
Knebel A, Haydon CE, Morrice N, Cohen P.
Biochem J. 2002 Oct 15;367(Pt 2):525-32.
PMID 12171600
A novel method to identify protein kinase substrates: eEF2 kinase is phosphorylated and inhibited by SAPK4/p38delta.
Knebel A, Morrice N, Cohen P.
EMBO J. 2001 Aug 15;20(16):4360-9.
PMID 11500363
Activation of PKCdelta and p38delta MAPK during okadaic acid dependent keratinocyte apoptosis.
Kraft CA, Efimova T, Eckert RL.
Arch Dermatol Res. 2007 May;299(2):71-83. Epub 2007 Jan 26.
PMID 17256148
Identification of stathmin as a novel substrate for p38 delta.
Parker CG, Hunt J, Diener K, McGinley M, Soriano B, Keesler GA, Bray J, Yao Z, Wang XS, Kohno T, Lichenstein HS.
Biochem Biophys Res Commun. 1998 Aug 28;249(3):791-6.
PMID 9731215
Differential activation of p38MAPK isoforms by MKK6 and MKK3.
Remy G, Risco AM, Inesta-Vaquera FA, Gonzalez-Teran B, Sabio G, Davis RJ, Cuenda A.
Cell Signal. 2009 Dec 11. [Epub ahead of print]
PMID 20004242
p38delta Mitogen-activated protein kinase is essential for skin tumor development in mice.
Schindler EM, Hindes A, Gribben EL, Burns CJ, Yin Y, Lin MH, Owen RJ, Longmore GD, Kissling GE, Arthur JS, Efimova T.
Cancer Res. 2009 Jun 1;69(11):4648-55. Epub 2009 May 19.
PMID 19458068
Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis.
Sumara G, Formentini I, Collins S, Sumara I, Windak R, Bodenmiller B, Ramracheya R, Caille D, Jiang H, Platt KA, Meda P, Aebersold R, Rorsman P, Ricci R.
Cell. 2009 Jan 23;136(2):235-48. Epub 2009 Jan 8.
PMID 19135240
p38delta/MAPK13 as a diagnostic marker for cholangiocarcinoma and its involvement in cell motility and invasion.
Tan FL, Ooi A, Huang D, Wong JC, Qian CN, Chao C, Ooi L, Tan YM, Chung A, Cheow PC, Zhang Z, Petillo D, Yang XJ, Teh BT.
Int J Cancer. 2009 Oct 8. [Epub ahead of print]
PMID 19816939
Signal integration by JNK and p38 MAPK pathways in cancer development.
Wagner EF, Nebreda AR.
Nat Rev Cancer. 2009 Aug;9(8):537-49. (REVIEW)
PMID 19629069
Melatonin arrests peroxynitrite-induced tau hyperphosphorylation and the overactivation of protein kinases in rat brain.
Yin J, Liu YH, Xu YF, Zhang YJ, Chen JG, Shu BH, Wang JZ.
J Pineal Res. 2006 Sep;41(2):124-9.
PMID 16879317
Sequential phosphorylation of tau protein by cAMP-dependent protein kinase and SAPK4/p38delta or JNK2 in the presence of heparin generates the AT100 epitope.
Yoshida H, Goedert M.
J Neurochem. 2006 Oct;99(1):154-64.
PMID 16987243
Activation of MKK6, an upstream activator of p38, in Alzheimer's disease.
Zhu X, Rottkamp CA, Hartzler A, Sun Z, Takeda A, Boux H, Shimohama S, Perry G, Smith MA.
J Neurochem. 2001 Oct;79(2):311-8.
PMID 11677259


This paper should be referenced as such :
Cerezo-Guisado, MI ; Cuenda, A
MAPK13 (mitogen-activated protein kinase 13)
Atlas Genet Cytogenet Oncol Haematol. 2010;14(10):911-914.
Free journal version : [ pdf ]   [ DOI ]

Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  dic(9;17)(p13;q11) PAX5::TAOK1
t(1;9)(q24;q34) RCSD1::ABL1

External links


HGNC (Hugo)MAPK13   6875
Entrez_Gene (NCBI)MAPK13    mitogen-activated protein kinase 13
AliasesMAPK; MAPK-13; PRKM13; SAPK4; 
GeneCards (Weizmann)MAPK13
Ensembl hg19 (Hinxton)ENSG00000156711 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000156711 [Gene_View]  ENSG00000156711 [Sequence]  chr6:36130513-36144521 [Contig_View]  MAPK13 [Vega]
ICGC DataPortalENSG00000156711
TCGA cBioPortalMAPK13
AceView (NCBI)MAPK13
Genatlas (Paris)MAPK13
SOURCE (Princeton)MAPK13
Genetics Home Reference (NIH)MAPK13
Genomic and cartography
GoldenPath hg38 (UCSC)MAPK13  -     chr6:36130513-36144521 +  6p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MAPK13  -     6p21.31   [Description]    (hg19-Feb_2009)
GoldenPathMAPK13 - 6p21.31 [CytoView hg19]  MAPK13 - 6p21.31 [CytoView hg38]
Genome Data Viewer NCBIMAPK13 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AB209586 AB451221 AB451344 AF004709 AF015256
RefSeq transcript (Entrez)NM_002754
Consensus coding sequences : CCDS (NCBI)MAPK13
Gene ExpressionMAPK13 [ NCBI-GEO ]   MAPK13 [ EBI - ARRAY_EXPRESS ]   MAPK13 [ SEEK ]   MAPK13 [ MEM ]
Gene Expression Viewer (FireBrowse)MAPK13 [ Firebrowse - Broad ]
GenevisibleExpression of MAPK13 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5603
GTEX Portal (Tissue expression)MAPK13
Human Protein AtlasENSG00000156711-MAPK13 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15264   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15264  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15264
Catalytic activity : Enzyme2.7.11.24 [ Enzyme-Expasy ] [ IntEnz-EBI ] [ BRENDA ] [ KEGG ]   [ MEROPS ]
Domaine pattern : Prosite (Expaxy)MAPK (PS01351)    PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)   
Domains : Interpro (EBI)Kinase-like_dom_sf    MAP_kinase_CS    MAPK_p38-like    p38delta    Prot_kinase_dom    Protein_kinase_ATP_BS   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
Conserved Domain (NCBI)MAPK13
PDB (RSDB)3COI    4EYJ    4EYM    4MYG    4YNO    5EKN    5EKO   
PDB Europe3COI    4EYJ    4EYM    4MYG    4YNO    5EKN    5EKO   
PDB (PDBSum)3COI    4EYJ    4EYM    4MYG    4YNO    5EKN    5EKO   
PDB (IMB)3COI    4EYJ    4EYM    4MYG    4YNO    5EKN    5EKO   
Structural Biology KnowledgeBase3COI    4EYJ    4EYM    4MYG    4YNO    5EKN    5EKO   
SCOP (Structural Classification of Proteins)3COI    4EYJ    4EYM    4MYG    4YNO    5EKN    5EKO   
CATH (Classification of proteins structures)3COI    4EYJ    4EYM    4MYG    4YNO    5EKN    5EKO   
AlphaFold pdb e-kbO15264   
Human Protein Atlas [tissue]ENSG00000156711-MAPK13 [tissue]
Protein Interaction databases
IntAct (EBI)O15264
Ontologies - Pathways
Ontology : AmiGOprotein serine/threonine kinase activity  protein serine/threonine kinase activity  MAP kinase activity  MAP kinase activity  protein binding  ATP binding  nucleus  cytoplasm  cytosol  response to osmotic stress  cell cycle  peptidyl-serine phosphorylation  positive regulation of interleukin-6 production  cellular response to UV  intracellular signal transduction  positive regulation of inflammatory response  stress-activated MAPK cascade  cellular response to hydrogen peroxide  cellular response to interleukin-1  cellular response to sorbitol  cellular response to anisomycin  protein serine kinase activity  protein threonine kinase activity  cellular response to sodium arsenite  
Ontology : EGO-EBIprotein serine/threonine kinase activity  protein serine/threonine kinase activity  MAP kinase activity  MAP kinase activity  protein binding  ATP binding  nucleus  cytoplasm  cytosol  response to osmotic stress  cell cycle  peptidyl-serine phosphorylation  positive regulation of interleukin-6 production  cellular response to UV  intracellular signal transduction  positive regulation of inflammatory response  stress-activated MAPK cascade  cellular response to hydrogen peroxide  cellular response to interleukin-1  cellular response to sorbitol  cellular response to anisomycin  protein serine kinase activity  protein threonine kinase activity  cellular response to sodium arsenite  
Pathways : BIOCARTAStathmin and breast cancer resistance to antimicrotubule agents [Genes]    Keratinocyte Differentiation [Genes]    MAPKinase Signaling Pathway [Genes]   
Pathways : KEGGMAPK signaling pathway    Rap1 signaling pathway    FoxO signaling pathway    Adrenergic signaling in cardiomyocytes    VEGF signaling pathway    Osteoclast differentiation    Toll-like receptor signaling pathway    NOD-like receptor signaling pathway    RIG-I-like receptor signaling pathway    T cell receptor signaling pathway    Fc epsilon RI signaling pathway    TNF signaling pathway    Leukocyte transendothelial migration    Neurotrophin signaling pathway    Retrograde endocannabinoid signaling    Dopaminergic synapse    GnRH signaling pathway    Progesterone-mediated oocyte maturation    Prolactin signaling pathway    Amyotrophic lateral sclerosis (ALS)    Epithelial cell signaling in Helicobacter pylori infection    Shigellosis    Salmonella infection    Pertussis    Leishmaniasis    Chagas disease (American trypanosomiasis)    Toxoplasmosis    Tuberculosis    Hepatitis C    Influenza A    Epstein-Barr virus infection    Proteoglycans in cancer   
REACTOMEO15264 [protein]
REACTOME PathwaysR-HSA-4420097 [pathway]   
NDEx NetworkMAPK13
Atlas of Cancer Signalling NetworkMAPK13
Wikipedia pathwaysMAPK13
Orthology - Evolution
GeneTree (enSembl)ENSG00000156711
Phylogenetic Trees/Animal Genes : TreeFamMAPK13
Homologs : HomoloGeneMAPK13
Homology/Alignments : Family Browser (UCSC)MAPK13
Gene fusions - Rearrangements
Fusion : FusionGDB2.7.11.1   
Fusion : QuiverMAPK13
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMAPK13 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MAPK13
Exome Variant ServerMAPK13
GNOMAD BrowserENSG00000156711
Varsome BrowserMAPK13
ACMGMAPK13 variants
Genomic Variants (DGV)MAPK13 [DGVbeta]
DECIPHERMAPK13 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMAPK13 
ICGC Data PortalMAPK13 
TCGA Data PortalMAPK13 
Broad Tumor PortalMAPK13
OASIS PortalMAPK13 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMAPK13  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMAPK13
Mutations and Diseases : HGMDMAPK13
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
DgiDB (Drug Gene Interaction Database)MAPK13
DoCM (Curated mutations)MAPK13
CIViC (Clinical Interpretations of Variants in Cancer)MAPK13
NCG (London)MAPK13
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Genetic Testing Registry MAPK13
NextProtO15264 [Medical]
Target ValidationMAPK13
Huge Navigator MAPK13 [HugePedia]
Clinical trials, drugs, therapy
Protein Interactions : CTDMAPK13
Pharm GKB GenePA30620
Pharm GKB PathwaysPA2032   
Clinical trialMAPK13
DataMed IndexMAPK13
PubMed86 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Oct 8 21:21:44 CEST 2021

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