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MAPK8IP3 (mitogen-activated protein kinase 8 interacting protein 3)

Identity

Alias_symbol (synonym)KIAA1066
JSAP1
JIP3
syd
Other aliasJIP-3
SYD2
HGNC (Hugo) MAPK8IP3
LocusID (NCBI) 23162
Atlas_Id 43350
Location 16p13.3  [Link to chromosome band 16p13]
Location_base_pair Starts at 1706220 and ends at 1770317 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MAPK8IP3 (16p13.3) / ANTXR1 (2p13.3)MAPK8IP3 (16p13.3) / GGA2 (16p12.2)MAPK8IP3 (16p13.3) / HN1L (16p13.3)
MAPK8IP3 (16p13.3) / IPO13 (1p34.1)MAPK8IP3 (16p13.3) / NXN (17p13.3)MAPK8IP3 (16p13.3) / TELO2 (16p13.3)
MAPK8IP3 (16p13.3) / TNRC18 (7p22.1)MAPK8IP3 16p13.3 / TELO2 16p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MAPK8IP3   6884
Cards
Entrez_Gene (NCBI)MAPK8IP3  23162  mitogen-activated protein kinase 8 interacting protein 3
AliasesJIP-3; JIP3; JSAP1; SYD2; 
syd
GeneCards (Weizmann)MAPK8IP3
Ensembl hg19 (Hinxton)ENSG00000138834 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138834 [Gene_View]  chr16:1706220-1770317 [Contig_View]  MAPK8IP3 [Vega]
ICGC DataPortalENSG00000138834
TCGA cBioPortalMAPK8IP3
AceView (NCBI)MAPK8IP3
Genatlas (Paris)MAPK8IP3
WikiGenes23162
SOURCE (Princeton)MAPK8IP3
Genetics Home Reference (NIH)MAPK8IP3
Genomic and cartography
GoldenPath hg38 (UCSC)MAPK8IP3  -     chr16:1706220-1770317 +  16p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MAPK8IP3  -     16p13.3   [Description]    (hg19-Feb_2009)
EnsemblMAPK8IP3 - 16p13.3 [CytoView hg19]  MAPK8IP3 - 16p13.3 [CytoView hg38]
Mapping of homologs : NCBIMAPK8IP3 [Mapview hg19]  MAPK8IP3 [Mapview hg38]
OMIM605431   
Gene and transcription
Genbank (Entrez)AB028989 AB621811 AI291346 AK024437 BC087861
RefSeq transcript (Entrez)NM_001040439 NM_001318852 NM_015133
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MAPK8IP3
Cluster EST : UnigeneHs.207763 [ NCBI ]
CGAP (NCI)Hs.207763
Alternative Splicing GalleryENSG00000138834
Gene ExpressionMAPK8IP3 [ NCBI-GEO ]   MAPK8IP3 [ EBI - ARRAY_EXPRESS ]   MAPK8IP3 [ SEEK ]   MAPK8IP3 [ MEM ]
Gene Expression Viewer (FireBrowse)MAPK8IP3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23162
GTEX Portal (Tissue expression)MAPK8IP3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UPT6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UPT6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UPT6
Splice isoforms : SwissVarQ9UPT6
PhosPhoSitePlusQ9UPT6
Domaine pattern : Prosite (Expaxy)RH1 (PS51776)    RH2 (PS51777)   
Domains : Interpro (EBI)JIP_LZII    JNK/Rab-associated_protein-1_N    WD40/YVTN_repeat-like_dom    WD40_repeat_dom   
Domain families : Pfam (Sanger)JIP_LZII (PF16471)    Jnk-SapK_ap_N (PF09744)   
Domain families : Pfam (NCBI)pfam16471    pfam09744   
Conserved Domain (NCBI)MAPK8IP3
DMDM Disease mutations23162
Blocks (Seattle)MAPK8IP3
PDB (SRS)4PXJ   
PDB (PDBSum)4PXJ   
PDB (IMB)4PXJ   
PDB (RSDB)4PXJ   
Structural Biology KnowledgeBase4PXJ   
SCOP (Structural Classification of Proteins)4PXJ   
CATH (Classification of proteins structures)4PXJ   
SuperfamilyQ9UPT6
Human Protein AtlasENSG00000138834
Peptide AtlasQ9UPT6
HPRD12014
IPIIPI00398504   IPI00219817   
Protein Interaction databases
DIP (DOE-UCLA)Q9UPT6
IntAct (EBI)Q9UPT6
FunCoupENSG00000138834
BioGRIDMAPK8IP3
STRING (EMBL)MAPK8IP3
ZODIACMAPK8IP3
Ontologies - Pathways
QuickGOQ9UPT6
Ontology : AmiGOGolgi membrane  MAP-kinase scaffold activity  MAP-kinase scaffold activity  protein binding  cytoplasm  activation of JUN kinase activity  JUN kinase binding  vesicle-mediated transport  vesicle-mediated transport  kinesin binding  kinesin binding  receptor signaling complex scaffold activity  regulation of JNK cascade  
Ontology : EGO-EBIGolgi membrane  MAP-kinase scaffold activity  MAP-kinase scaffold activity  protein binding  cytoplasm  activation of JUN kinase activity  JUN kinase binding  vesicle-mediated transport  vesicle-mediated transport  kinesin binding  kinesin binding  receptor signaling complex scaffold activity  regulation of JNK cascade  
Pathways : KEGGMAPK signaling pathway   
NDEx NetworkMAPK8IP3
Atlas of Cancer Signalling NetworkMAPK8IP3
Wikipedia pathwaysMAPK8IP3
Orthology - Evolution
OrthoDB23162
GeneTree (enSembl)ENSG00000138834
Phylogenetic Trees/Animal Genes : TreeFamMAPK8IP3
HOVERGENQ9UPT6
HOGENOMQ9UPT6
Homologs : HomoloGeneMAPK8IP3
Homology/Alignments : Family Browser (UCSC)MAPK8IP3
Gene fusions - Rearrangements
Fusion : MitelmanMAPK8IP3/TELO2 [16p13.3/16p13.3]  
Fusion: TCGAMAPK8IP3 16p13.3 TELO2 16p13.3 PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMAPK8IP3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MAPK8IP3
dbVarMAPK8IP3
ClinVarMAPK8IP3
1000_GenomesMAPK8IP3 
Exome Variant ServerMAPK8IP3
ExAC (Exome Aggregation Consortium)MAPK8IP3 (select the gene name)
Genetic variants : HAPMAP23162
Genomic Variants (DGV)MAPK8IP3 [DGVbeta]
DECIPHERMAPK8IP3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMAPK8IP3 
Mutations
ICGC Data PortalMAPK8IP3 
TCGA Data PortalMAPK8IP3 
Broad Tumor PortalMAPK8IP3
OASIS PortalMAPK8IP3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMAPK8IP3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMAPK8IP3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MAPK8IP3
DgiDB (Drug Gene Interaction Database)MAPK8IP3
DoCM (Curated mutations)MAPK8IP3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MAPK8IP3 (select a term)
intoGenMAPK8IP3
Cancer3DMAPK8IP3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605431   
Orphanet
MedgenMAPK8IP3
Genetic Testing Registry MAPK8IP3
NextProtQ9UPT6 [Medical]
TSGene23162
GENETestsMAPK8IP3
Target ValidationMAPK8IP3
Huge Navigator MAPK8IP3 [HugePedia]
snp3D : Map Gene to Disease23162
BioCentury BCIQMAPK8IP3
ClinGenMAPK8IP3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23162
Chemical/Pharm GKB GenePA30628
Clinical trialMAPK8IP3
Miscellaneous
canSAR (ICR)MAPK8IP3 (select the gene name)
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMAPK8IP3
EVEXMAPK8IP3
GoPubMedMAPK8IP3
iHOPMAPK8IP3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:58:44 CEST 2017

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