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MAPRE2 (microtubule associated protein RP/EB family member 2)

Identity

Alias_symbol (synonym)RP1
EB1
EB2
Other aliasCSCSC2
HGNC (Hugo) MAPRE2
LocusID (NCBI) 10982
Atlas_Id 41297
Location 18q12.1  [Link to chromosome band 18q12]
Location_base_pair Starts at 32556892 and ends at 32723432 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ELP2 (18q12.2) / MAPRE2 (18q12.1)MAPRE2 (18q12.1) / GAB1 (4q31.21)MAPRE2 (18q12.1) / MAPRE2 (18q12.1)
ELP2 18q12.2 / MAPRE2 18q12.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MAPRE2   6891
Cards
Entrez_Gene (NCBI)MAPRE2  10982  microtubule associated protein RP/EB family member 2
AliasesCSCSC2; EB1; EB2; RP1
GeneCards (Weizmann)MAPRE2
Ensembl hg19 (Hinxton)ENSG00000166974 [Gene_View]  chr18:32556892-32723432 [Contig_View]  MAPRE2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000166974 [Gene_View]  chr18:32556892-32723432 [Contig_View]  MAPRE2 [Vega]
ICGC DataPortalENSG00000166974
TCGA cBioPortalMAPRE2
AceView (NCBI)MAPRE2
Genatlas (Paris)MAPRE2
WikiGenes10982
SOURCE (Princeton)MAPRE2
Genetics Home Reference (NIH)MAPRE2
Genomic and cartography
GoldenPath hg19 (UCSC)MAPRE2  -     chr18:32556892-32723432 +  18q12.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MAPRE2  -     18q12.1   [Description]    (hg38-Dec_2013)
EnsemblMAPRE2 - 18q12.1 [CytoView hg19]  MAPRE2 - 18q12.1 [CytoView hg38]
Mapping of homologs : NCBIMAPRE2 [Mapview hg19]  MAPRE2 [Mapview hg38]
OMIM605789   
Gene and transcription
Genbank (Entrez)AB016823 AK090945 AK294833 AK296251 AK315766
RefSeq transcript (Entrez)NM_001143826 NM_001143827 NM_001256420 NM_014268
RefSeq genomic (Entrez)NC_000018 NC_018929 NT_010966 NW_004929410
Consensus coding sequences : CCDS (NCBI)MAPRE2
Cluster EST : UnigeneHs.532824 [ NCBI ]
CGAP (NCI)Hs.532824
Alternative Splicing GalleryENSG00000166974
Gene ExpressionMAPRE2 [ NCBI-GEO ]   MAPRE2 [ EBI - ARRAY_EXPRESS ]   MAPRE2 [ SEEK ]   MAPRE2 [ MEM ]
Gene Expression Viewer (FireBrowse)MAPRE2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10982
GTEX Portal (Tissue expression)MAPRE2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15555   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15555  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15555
Splice isoforms : SwissVarQ15555
PhosPhoSitePlusQ15555
Domaine pattern : Prosite (Expaxy)CH (PS50021)    EB1_C (PS51230)   
Domains : Interpro (EBI)CH-domain    EB1_C    MAPRE    RP1/EB2_vertebrate   
Domain families : Pfam (Sanger)CH (PF00307)    EB1 (PF03271)   
Domain families : Pfam (NCBI)pfam00307    pfam03271   
Conserved Domain (NCBI)MAPRE2
DMDM Disease mutations10982
Blocks (Seattle)MAPRE2
SuperfamilyQ15555
Human Protein AtlasENSG00000166974
Peptide AtlasQ15555
HPRD16157
IPIIPI00003420   IPI00552652   IPI00903288   IPI00915767   IPI00916186   
Protein Interaction databases
DIP (DOE-UCLA)Q15555
IntAct (EBI)Q15555
FunCoupENSG00000166974
BioGRIDMAPRE2
STRING (EMBL)MAPRE2
ZODIACMAPRE2
Ontologies - Pathways
QuickGOQ15555
Ontology : AmiGOprotein binding  cytoplasm  mitotic nuclear division  signal transduction  microtubule binding  cell proliferation  microtubule cytoskeleton  microtubule plus-end  cell division  
Ontology : EGO-EBIprotein binding  cytoplasm  mitotic nuclear division  signal transduction  microtubule binding  cell proliferation  microtubule cytoskeleton  microtubule plus-end  cell division  
NDEx NetworkMAPRE2
Atlas of Cancer Signalling NetworkMAPRE2
Wikipedia pathwaysMAPRE2
Orthology - Evolution
OrthoDB10982
GeneTree (enSembl)ENSG00000166974
Phylogenetic Trees/Animal Genes : TreeFamMAPRE2
HOVERGENQ15555
HOGENOMQ15555
Homologs : HomoloGeneMAPRE2
Homology/Alignments : Family Browser (UCSC)MAPRE2
Gene fusions - Rearrangements
Fusion : MitelmanELP2/MAPRE2 [18q12.2/18q12.1]  [t(18;18)(q12;q12)]  
Fusion: TCGAELP2 18q12.2 MAPRE2 18q12.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMAPRE2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MAPRE2
dbVarMAPRE2
ClinVarMAPRE2
1000_GenomesMAPRE2 
Exome Variant ServerMAPRE2
ExAC (Exome Aggregation Consortium)MAPRE2 (select the gene name)
Genetic variants : HAPMAP10982
Genomic Variants (DGV)MAPRE2 [DGVbeta]
DECIPHER (Syndromes)18:32556892-32723432  ENSG00000166974
CONAN: Copy Number AnalysisMAPRE2 
Mutations
ICGC Data PortalMAPRE2 
TCGA Data PortalMAPRE2 
Broad Tumor PortalMAPRE2
OASIS PortalMAPRE2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMAPRE2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMAPRE2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MAPRE2
DgiDB (Drug Gene Interaction Database)MAPRE2
DoCM (Curated mutations)MAPRE2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MAPRE2 (select a term)
intoGenMAPRE2
Cancer3DMAPRE2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605789   
Orphanet2317   
MedgenMAPRE2
Genetic Testing Registry MAPRE2
NextProtQ15555 [Medical]
TSGene10982
GENETestsMAPRE2
Huge Navigator MAPRE2 [HugePedia]
snp3D : Map Gene to Disease10982
BioCentury BCIQMAPRE2
ClinGenMAPRE2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10982
Chemical/Pharm GKB GenePA30635
Clinical trialMAPRE2
Miscellaneous
canSAR (ICR)MAPRE2 (select the gene name)
Probes
Litterature
PubMed54 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMAPRE2
EVEXMAPRE2
GoPubMedMAPRE2
iHOPMAPRE2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:14:32 CET 2017

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