MAPRE3 (microtubule associated protein RP/EB family member 3)

2003-06-01  

Identity

HGNC
LOCATION
2p23.3
LOCUSID
ALIAS
EB3,EBF3,EBF3-S,RP3
FUSION GENES

Other Information

Locus ID:

NCBI: 22924
MIM: 605788
HGNC: 6892
Ensembl: ENSG00000084764

Variants:

dbSNP: 22924
ClinVar: 22924
TCGA: ENSG00000084764
COSMIC: MAPRE3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000084764ENST00000233121Q9UPY8
ENSG00000084764ENST00000402218Q9UPY8
ENSG00000084764ENST00000405074Q9UPY8
ENSG00000084764ENST00000458529C9JB30
ENSG00000084764ENST00000648289Q9UPY8

Expression (GTEx)

0
50
100
150
200
250

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
192552452009Mammalian end binding proteins control persistent microtubule growth.149
217683262011EB1 and EB3 promote cilia biogenesis by several centrosome-related mechanisms.49
145146682003Characterization of functional domains of human EB1 family proteins.35
196960282009Mitotic regulation of the stability of microtubule plus-end tracking protein EB3 by ubiquitin ligase SIAH-1 and Aurora mitotic kinases.26
200083242010Molecular insights into mammalian end-binding protein heterodimerization.26
237122602013Aurora B spatially regulates EB3 phosphorylation to coordinate daughter cell adhesion with cytokinesis.26
231597402012VE-cadherin signaling induces EB3 phosphorylation to suppress microtubule growth and assemble adherens junctions.22
288145702017EB1 and EB3 regulate microtubule minus end organization and Golgi morphology.15
222754342012Apico-basal elongation requires a drebrin-E-EB3 complex in columnar human epithelial cells.11
240402502013End binding proteins are obligatory dimers.11

Citation

Dessen P

MAPRE3 (microtubule associated protein RP/EB family member 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41298/mapre3