Identity
HGNC
LOCATION
17q21.31
LOCUSID
ALIAS
DDPAC,FTDP-17,MAPTL,MSTD,MTBT1,MTBT2,PPND,PPP1R103,TAU,tau-40
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4137
MIM: 157140
HGNC: 6893
Ensembl: ENSG00000186868
Variants:
dbSNP: 4137
ClinVar: 4137
TCGA: ENSG00000186868
COSMIC: MAPT
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37264610 | 2024 | Tau in dementia with Lewy bodies. | 1 |
| 37530894 | 2024 | Associations of plasma NfL, GFAP, and t-tau with cerebral small vessel disease and incident dementia: longitudinal data of the AGES-Reykjavik Study. | 2 |
| 37577852 | 2024 | The relationship between APOE genotype, CSF Tau and cognition across the Alzheimer's disease spectrum, moderation and mediation role of insula network connectivity. | 1 |
| 37633469 | 2024 | Abnormal interaction of Rlip with mutant APP/Abeta and phosphorylated tau reduces wild-type Rlip levels and disrupt Rlip function in Alzheimer's disease. | 0 |
| 37639492 | 2024 | Plasma phosphorylated tau-217 exhibits sex-specific prognostication of cognitive decline and brain atrophy in cognitively unimpaired adults. | 4 |
| 37641913 | 2024 | Activation of transient receptor potential vanilloid 1 ameliorates tau accumulation-induced synaptic damage and cognitive dysfunction via autophagy enhancement. | 2 |
| 37703311 | 2024 | Glial reactivity and T cell infiltration in frontotemporal lobar degeneration with tau pathology. | 1 |
| 37725589 | 2024 | Temporal Profiles of P-Tau, T-Tau, and P-Tau:Tau Ratios in Cerebrospinal Fluid and Blood from Moderate-Severe Traumatic Brain Injury Patients and Relationship to 6-12 Month Global Outcomes. | 2 |
| 37820751 | 2024 | Apathy-like behaviour in tau mouse models of Alzheimer's disease and frontotemporal dementia. | 0 |
| 37837382 | 2024 | Combined Connectomics, MAPT Gene Expression, and Amyloid Deposition to Explain Regional Tau Deposition in Alzheimer Disease. | 1 |
| 37955806 | 2024 | DLK-MAPK Signaling Coupled with DNA Damage Promotes Intrinsic Neurotoxicity Associated with Non-Mutated Tau. | 3 |
| 37988169 | 2024 | Galectin-3 aggravates microglial activation and tau transmission in tauopathy. | 1 |
| 38073060 | 2024 | Tau and neurodegeneration. | 4 |
| 38086389 | 2024 | APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread. | 9 |
| 38123362 | 2024 | Spatiotemporal Correlation between Amyloid and Tau Accumulations Underlies Cognitive Changes in Aging. | 0 |
Citation
Dessen P
MAPT (microtubule associated protein tau)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/41299/mapt
