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MARC2 (mitochondrial amidoxime reducing component 2)

Identity

Alias_namesMOSC2
MOCO sulphurase C-terminal domain containing 2
Alias_symbol (synonym)FLJ20605
Other alias
HGNC (Hugo) 2-Mar
LocusID (NCBI) 54996
Atlas_Id 68805
Location 1q41  [Link to chromosome band 1q41]
Location_base_pair Starts at 220748246 and ends at 220784815 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MACF1 (1p34.3) / MARC2 (1q41)MARC2 (1q41) / C1orf143 ()PLCD4 (2q35) / MARC2 (1q41)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)2-Mar   26064
Cards
Entrez_Gene (NCBI)MARC2  54996  mitochondrial amidoxime reducing component 2
AliasesMOSC2
GeneCards (Weizmann)MARC2
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr1:220748246-220784815 [Contig_View]  MARC2 [Vega]
TCGA cBioPortalMARC2
AceView (NCBI)MARC2
Genatlas (Paris)MARC2
WikiGenes54996
SOURCE (Princeton)MARC2
Genetics Home Reference (NIH)MARC2
Genomic and cartography
GoldenPath hg38 (UCSC)MARC2  -     chr1:220748246-220784815 +  1q41   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MARC2  -     1q41   [Description]    (hg19-Feb_2009)
EnsemblMARC2 - 1q41 [CytoView hg19]  MARC2 - 1q41 [CytoView hg38]
Mapping of homologs : NCBIMARC2 [Mapview hg19]  MARC2 [Mapview hg38]
OMIM614127   
Gene and transcription
Genbank (Entrez)AA843271 AK000583 AK000612 AL136931 AM393019
RefSeq transcript (Entrez)NM_001317338 NM_001331042 NM_017898
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MARC2
Cluster EST : UnigeneHs.369042 [ NCBI ]
CGAP (NCI)Hs.369042
Gene ExpressionMARC2 [ NCBI-GEO ]   MARC2 [ EBI - ARRAY_EXPRESS ]   MARC2 [ SEEK ]   MARC2 [ MEM ]
Gene Expression Viewer (FireBrowse)MARC2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54996
GTEX Portal (Tissue expression)MARC2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ969Z3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ969Z3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ969Z3
Splice isoforms : SwissVarQ969Z3
Catalytic activity : Enzyme1.-.-.- [ Enzyme-Expasy ]   1.-.-.-1.-.-.- [ IntEnz-EBI ]   1.-.-.- [ BRENDA ]   1.-.-.- [ KEGG ]   
PhosPhoSitePlusQ969Z3
Domaine pattern : Prosite (Expaxy)MOSC (PS51340)   
Domains : Interpro (EBI)MoCF_Sase_C    MOSC_N    Pyrv_Knase-like_insert_dom   
Domain families : Pfam (Sanger)MOSC (PF03473)    MOSC_N (PF03476)   
Domain families : Pfam (NCBI)pfam03473    pfam03476   
Conserved Domain (NCBI)MARC2
DMDM Disease mutations54996
Blocks (Seattle)MARC2
SuperfamilyQ969Z3
Peptide AtlasQ969Z3
HPRD08628
IPIIPI00329552   IPI00827858   IPI00980402   IPI00640673   
Protein Interaction databases
DIP (DOE-UCLA)Q969Z3
IntAct (EBI)Q969Z3
BioGRIDMARC2
STRING (EMBL)MARC2
ZODIACMARC2
Ontologies - Pathways
QuickGOQ969Z3
Ontology : AmiGOmitochondrion  mitochondrion  mitochondrial outer membrane  mitochondrial inner membrane  peroxisome  xenobiotic metabolic process  nitrate reductase activity  molybdenum ion binding  pyridoxal phosphate binding  nitrate metabolic process  molybdopterin cofactor binding  detoxification of nitrogen compound  oxidation-reduction process  extracellular exosome  
Ontology : EGO-EBImitochondrion  mitochondrion  mitochondrial outer membrane  mitochondrial inner membrane  peroxisome  xenobiotic metabolic process  nitrate reductase activity  molybdenum ion binding  pyridoxal phosphate binding  nitrate metabolic process  molybdopterin cofactor binding  detoxification of nitrogen compound  oxidation-reduction process  extracellular exosome  
NDEx NetworkMARC2
Atlas of Cancer Signalling NetworkMARC2
Wikipedia pathwaysMARC2
Orthology - Evolution
OrthoDB54996
Phylogenetic Trees/Animal Genes : TreeFam2-Mar
HOVERGENQ969Z3
HOGENOMQ969Z3
Homologs : HomoloGeneMARC2
Homology/Alignments : Family Browser (UCSC)MARC2
Gene fusions - Rearrangements
Fusion: Tumor Portal MARC2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMARC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MARC2
dbVarMARC2
ClinVarMARC2
1000_GenomesMARC2 
Exome Variant ServerMARC2
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP54996
Genomic Variants (DGV)MARC2 [DGVbeta]
DECIPHERMARC2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMARC2 
Mutations
ICGC Data Portal2-Mar 
TCGA Data Portal2-Mar 
Broad Tumor Portal2-Mar
OASIS Portal2-Mar [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMARC2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMD2-Mar
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MARC2
DgiDB (Drug Gene Interaction Database)MARC2
DoCM (Curated mutations)MARC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MARC2 (select a term)
intoGenMARC2
Cancer3DMARC2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614127   
Orphanet
MedgenMARC2
Genetic Testing Registry MARC2
NextProtQ969Z3 [Medical]
TSGene54996
GENETestsMARC2
Target ValidationMARC2
Huge Navigator 2-Mar [HugePedia]
snp3D : Map Gene to Disease54996
BioCentury BCIQMARC2
ClinGenMARC2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54996
Chemical/Pharm GKB GenePA142671345
Clinical trialMARC2
Miscellaneous
canSAR (ICR)MARC2 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMARC2
EVEXMARC2
GoPubMedMARC2
iHOPMARC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:12:14 CET 2017

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