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MARCH1 (membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase)

Identity

Alias_namesmembrane-associated ring finger (C3HC4) 1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
Alias_symbol (synonym)FLJ20668
MARCH-I
RNF171
Other alias
HGNC (Hugo) MARCH1
LocusID (NCBI) 55016
Atlas_Id 68806
Location 4q32.2  [Link to chromosome band 4q32]
Location_base_pair Starts at 164445450 and ends at 165304407 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MARCH1 (4q32.2) / PTPN13 (4q21.3)MARCH1 (4q32.2) / SKP1 (5q31.1)PSMB7 (9q33.3) / MARCH1 (4q32.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MARCH1   26077
Cards
Entrez_Gene (NCBI)MARCH1  55016  membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
AliasesMARCH-I; RNF171
GeneCards (Weizmann)MARCH1
Ensembl hg19 (Hinxton)ENSG00000145416 [Gene_View]  chr4:164445450-165304407 [Contig_View]  MARCH1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000145416 [Gene_View]  chr4:164445450-165304407 [Contig_View]  MARCH1 [Vega]
ICGC DataPortalENSG00000145416
TCGA cBioPortalMARCH1
AceView (NCBI)MARCH1
Genatlas (Paris)MARCH1
WikiGenes55016
SOURCE (Princeton)MARCH1
Genetics Home Reference (NIH)MARCH1
Genomic and cartography
GoldenPath hg19 (UCSC)MARCH1  -     chr4:164445450-165304407 -  4q32.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MARCH1  -     4q32.2   [Description]    (hg38-Dec_2013)
EnsemblMARCH1 - 4q32.2 [CytoView hg19]  MARCH1 - 4q32.2 [CytoView hg38]
Mapping of homologs : NCBIMARCH1 [Mapview hg19]  MARCH1 [Mapview hg38]
OMIM613331   
Gene and transcription
Genbank (Entrez)AK000675 AK025005 AK091335 AK289711 AK301408
RefSeq transcript (Entrez)NM_001166373 NM_017923
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)MARCH1
Cluster EST : UnigeneHs.608487 [ NCBI ]
CGAP (NCI)Hs.608487
Alternative Splicing GalleryENSG00000145416
Gene ExpressionMARCH1 [ NCBI-GEO ]   MARCH1 [ EBI - ARRAY_EXPRESS ]   MARCH1 [ SEEK ]   MARCH1 [ MEM ]
Gene Expression Viewer (FireBrowse)MARCH1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55016
GTEX Portal (Tissue expression)MARCH1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TCQ1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TCQ1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TCQ1
Splice isoforms : SwissVarQ8TCQ1
Catalytic activity : Enzyme6.3.2.- [ Enzyme-Expasy ]   6.3.2.-6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   
PhosPhoSitePlusQ8TCQ1
Domaine pattern : Prosite (Expaxy)ZF_RING_CH (PS51292)   
Domains : Interpro (EBI)Znf_RING-CH    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)RINGv (PF12906)   
Domain families : Pfam (NCBI)pfam12906   
Domain families : Smart (EMBL)RINGv (SM00744)  
Conserved Domain (NCBI)MARCH1
DMDM Disease mutations55016
Blocks (Seattle)MARCH1
SuperfamilyQ8TCQ1
Human Protein AtlasENSG00000145416
Peptide AtlasQ8TCQ1
HPRD07940
IPIIPI00382922   IPI00016724   IPI00965590   IPI00922039   IPI00965098   
Protein Interaction databases
DIP (DOE-UCLA)Q8TCQ1
IntAct (EBI)Q8TCQ1
FunCoupENSG00000145416
BioGRIDMARCH1
STRING (EMBL)MARCH1
ZODIACMARCH1
Ontologies - Pathways
QuickGOQ8TCQ1
Ontology : AmiGOprotein polyubiquitination  antigen processing and presentation of peptide antigen via MHC class II  ubiquitin-protein transferase activity  lysosome  lysosomal membrane  endosome  endoplasmic reticulum membrane  plasma membrane  immune response  zinc ion binding  integral component of membrane  ligase activity  cytoplasmic vesicle membrane  early endosome membrane  late endosome membrane  trans-Golgi network membrane  MHC protein binding  
Ontology : EGO-EBIprotein polyubiquitination  antigen processing and presentation of peptide antigen via MHC class II  ubiquitin-protein transferase activity  lysosome  lysosomal membrane  endosome  endoplasmic reticulum membrane  plasma membrane  immune response  zinc ion binding  integral component of membrane  ligase activity  cytoplasmic vesicle membrane  early endosome membrane  late endosome membrane  trans-Golgi network membrane  MHC protein binding  
NDEx NetworkMARCH1
Atlas of Cancer Signalling NetworkMARCH1
Wikipedia pathwaysMARCH1
Orthology - Evolution
OrthoDB55016
GeneTree (enSembl)ENSG00000145416
Phylogenetic Trees/Animal Genes : TreeFamMARCH1
HOVERGENQ8TCQ1
HOGENOMQ8TCQ1
Homologs : HomoloGeneMARCH1
Homology/Alignments : Family Browser (UCSC)MARCH1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMARCH1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MARCH1
dbVarMARCH1
ClinVarMARCH1
1000_GenomesMARCH1 
Exome Variant ServerMARCH1
ExAC (Exome Aggregation Consortium)MARCH1 (select the gene name)
Genetic variants : HAPMAP55016
Genomic Variants (DGV)MARCH1 [DGVbeta]
DECIPHER (Syndromes)4:164445450-165304407  ENSG00000145416
CONAN: Copy Number AnalysisMARCH1 
Mutations
ICGC Data PortalMARCH1 
TCGA Data PortalMARCH1 
Broad Tumor PortalMARCH1
OASIS PortalMARCH1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMARCH1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMARCH1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MARCH1
DgiDB (Drug Gene Interaction Database)MARCH1
DoCM (Curated mutations)MARCH1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MARCH1 (select a term)
intoGenMARCH1
Cancer3DMARCH1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613331   
Orphanet
MedgenMARCH1
Genetic Testing Registry MARCH1
NextProtQ8TCQ1 [Medical]
TSGene55016
GENETestsMARCH1
Huge Navigator MARCH1 [HugePedia]
snp3D : Map Gene to Disease55016
BioCentury BCIQMARCH1
ClinGenMARCH1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55016
Chemical/Pharm GKB GenePA134986392
Clinical trialMARCH1
Miscellaneous
canSAR (ICR)MARCH1 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMARCH1
EVEXMARCH1
GoPubMedMARCH1
iHOPMARCH1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:27:43 CET 2017

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