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MARCH10 (membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase)

Identity

Alias_namesRNF190
ring finger protein 190
membrane-associated ring finger (C3HC4) 10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
Alias_symbol (synonym)FLJ35757
MARCH-X
Other alias
HGNC (Hugo) MARCH10
LocusID (NCBI) 162333
Atlas_Id 68807
Location 17q23.2  [Link to chromosome band 17q23]
Location_base_pair Starts at 60778675 and ends at 60884014 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
BCAS3 (17q23.2) / MARCH10 (17q23.2)CUX1 (7q22.1) / MARCH10 (17q23.2)DLG4 (17p13.1) / MARCH10 (17q23.2)
MAPT (17q21.31) / MARCH10 (17q23.2)PITPNC1 (17q24.2) / MARCH10 (17q23.2)VMP1 (17q23.1) / MARCH10 (17q23.2)
CUX1 MARCH10MAPT MARCH10VMP1 MARCH10
PITPNC1 MARCH10DLG4 MARCH10BCAS3 MARCH10

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MARCH10   26655
Cards
Entrez_Gene (NCBI)MARCH10  162333  membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
AliasesMARCH-X; RNF190
GeneCards (Weizmann)MARCH10
Ensembl hg19 (Hinxton)ENSG00000173838 [Gene_View]  chr17:60778675-60884014 [Contig_View]  MARCH10 [Vega]
Ensembl hg38 (Hinxton)ENSG00000173838 [Gene_View]  chr17:60778675-60884014 [Contig_View]  MARCH10 [Vega]
ICGC DataPortalENSG00000173838
TCGA cBioPortalMARCH10
AceView (NCBI)MARCH10
Genatlas (Paris)MARCH10
WikiGenes162333
SOURCE (Princeton)MARCH10
Genetics Home Reference (NIH)MARCH10
Genomic and cartography
GoldenPath hg19 (UCSC)MARCH10  -     chr17:60778675-60884014 -  17q23.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)MARCH10  -     17q23.2   [Description]    (hg38-Dec_2013)
EnsemblMARCH10 - 17q23.2 [CytoView hg19]  MARCH10 - 17q23.2 [CytoView hg38]
Mapping of homologs : NCBIMARCH10 [Mapview hg19]  MARCH10 [Mapview hg38]
OMIM613337   
Gene and transcription
Genbank (Entrez)AI223162 AI262871 AK093076 AK097506 AK122947
RefSeq transcript (Entrez)NM_001100875 NM_001288779 NM_001288780 NM_152598
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)MARCH10
Cluster EST : UnigeneHs.665663 [ NCBI ]
CGAP (NCI)Hs.665663
Alternative Splicing GalleryENSG00000173838
Gene ExpressionMARCH10 [ NCBI-GEO ]   MARCH10 [ EBI - ARRAY_EXPRESS ]   MARCH10 [ SEEK ]   MARCH10 [ MEM ]
Gene Expression Viewer (FireBrowse)MARCH10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)162333
GTEX Portal (Tissue expression)MARCH10
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NA82   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NA82  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NA82
Splice isoforms : SwissVarQ8NA82
Catalytic activity : Enzyme6.3.2.- [ Enzyme-Expasy ]   6.3.2.-6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   
PhosPhoSitePlusQ8NA82
Domaine pattern : Prosite (Expaxy)ZF_RING_CH (PS51292)   
Domains : Interpro (EBI)Znf_RING-CH    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)RINGv (PF12906)   
Domain families : Pfam (NCBI)pfam12906   
Domain families : Smart (EMBL)RINGv (SM00744)  
Conserved Domain (NCBI)MARCH10
DMDM Disease mutations162333
Blocks (Seattle)MARCH10
SuperfamilyQ8NA82
Human Protein AtlasENSG00000173838
Peptide AtlasQ8NA82
HPRD08762
IPIIPI00793949   IPI00966809   
Protein Interaction databases
DIP (DOE-UCLA)Q8NA82
IntAct (EBI)Q8NA82
FunCoupENSG00000173838
BioGRIDMARCH10
STRING (EMBL)MARCH10
ZODIACMARCH10
Ontologies - Pathways
QuickGOQ8NA82
Ontology : AmiGOprotein binding  zinc ion binding  protein ubiquitination  ligase activity  
Ontology : EGO-EBIprotein binding  zinc ion binding  protein ubiquitination  ligase activity  
NDEx NetworkMARCH10
Atlas of Cancer Signalling NetworkMARCH10
Wikipedia pathwaysMARCH10
Orthology - Evolution
OrthoDB162333
GeneTree (enSembl)ENSG00000173838
Phylogenetic Trees/Animal Genes : TreeFamMARCH10
HOVERGENQ8NA82
HOGENOMQ8NA82
Homologs : HomoloGeneMARCH10
Homology/Alignments : Family Browser (UCSC)MARCH10
Gene fusions - Rearrangements
Fusion: TCGACUX1 MARCH10
Fusion: TCGAMAPT MARCH10
Fusion: TCGAVMP1 MARCH10
Fusion: TCGAPITPNC1 MARCH10
Fusion: TCGADLG4 MARCH10
Fusion: TCGABCAS3 MARCH10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMARCH10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MARCH10
dbVarMARCH10
ClinVarMARCH10
1000_GenomesMARCH10 
Exome Variant ServerMARCH10
ExAC (Exome Aggregation Consortium)MARCH10 (select the gene name)
Genetic variants : HAPMAP162333
Genomic Variants (DGV)MARCH10 [DGVbeta]
DECIPHER (Syndromes)17:60778675-60884014  ENSG00000173838
CONAN: Copy Number AnalysisMARCH10 
Mutations
ICGC Data PortalMARCH10 
TCGA Data PortalMARCH10 
Broad Tumor PortalMARCH10
OASIS PortalMARCH10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMARCH10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMARCH10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MARCH10
DgiDB (Drug Gene Interaction Database)MARCH10
DoCM (Curated mutations)MARCH10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MARCH10 (select a term)
intoGenMARCH10
Cancer3DMARCH10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613337   
Orphanet
MedgenMARCH10
Genetic Testing Registry MARCH10
NextProtQ8NA82 [Medical]
TSGene162333
GENETestsMARCH10
Huge Navigator MARCH10 [HugePedia]
snp3D : Map Gene to Disease162333
BioCentury BCIQMARCH10
ClinGenMARCH10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD162333
Chemical/Pharm GKB GenePA162395028
Clinical trialMARCH10
Miscellaneous
canSAR (ICR)MARCH10 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMARCH10
EVEXMARCH10
GoPubMedMARCH10
iHOPMARCH10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:27:43 CET 2017

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