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MARCH3 (membrane associated ring-CH-type finger 3)

Identity

Alias_namesmembrane-associated ring finger (C3HC4) 3
membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
Alias_symbol (synonym)MGC48332
MARCH-III
RNF173
Other alias
HGNC (Hugo) 3-Mar
LocusID (NCBI) 115123
Atlas_Id 68810
Location 5q23.2  [Link to chromosome band 5q23]
Location_base_pair Starts at 126867714 and ends at 127030808 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)3-Mar   28728
Cards
Entrez_Gene (NCBI)MARCH3  115123  membrane associated ring-CH-type finger 3
AliasesMARCH-III; RNF173
GeneCards (Weizmann)MARCH3
Ensembl hg19 (Hinxton)ENSG00000173926 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173926 [Gene_View]  chr5:126867714-127030808 [Contig_View]  MARCH3 [Vega]
ICGC DataPortalENSG00000173926
TCGA cBioPortalMARCH3
AceView (NCBI)MARCH3
Genatlas (Paris)MARCH3
WikiGenes115123
SOURCE (Princeton)MARCH3
Genetics Home Reference (NIH)MARCH3
Genomic and cartography
GoldenPath hg38 (UCSC)MARCH3  -     chr5:126867714-127030808 -  5q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MARCH3  -     5q23.2   [Description]    (hg19-Feb_2009)
EnsemblMARCH3 - 5q23.2 [CytoView hg19]  MARCH3 - 5q23.2 [CytoView hg38]
Mapping of homologs : NCBIMARCH3 [Mapview hg19]  MARCH3 [Mapview hg38]
OMIM613333   
Gene and transcription
Genbank (Entrez)AF055007 AK000103 AK290129 BC047569 BC146948
RefSeq transcript (Entrez)NM_178450
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MARCH3
Cluster EST : UnigeneHs.132441 [ NCBI ]
CGAP (NCI)Hs.132441
Alternative Splicing GalleryENSG00000173926
Gene ExpressionMARCH3 [ NCBI-GEO ]   MARCH3 [ EBI - ARRAY_EXPRESS ]   MARCH3 [ SEEK ]   MARCH3 [ MEM ]
Gene Expression Viewer (FireBrowse)MARCH3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)115123
GTEX Portal (Tissue expression)MARCH3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86UD3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86UD3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86UD3
Splice isoforms : SwissVarQ86UD3
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   
PhosPhoSitePlusQ86UD3
Domaine pattern : Prosite (Expaxy)ZF_RING_CH (PS51292)   
Domains : Interpro (EBI)MARCH-like    Znf_RING-CH    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)RINGv (PF12906)   
Domain families : Pfam (NCBI)pfam12906   
Domain families : Smart (EMBL)RINGv (SM00744)  
Conserved Domain (NCBI)MARCH3
DMDM Disease mutations115123
Blocks (Seattle)MARCH3
SuperfamilyQ86UD3
Human Protein AtlasENSG00000173926
Peptide AtlasQ86UD3
HPRD14362
IPIIPI00033653   IPI00967817   
Protein Interaction databases
DIP (DOE-UCLA)Q86UD3
IntAct (EBI)Q86UD3
FunCoupENSG00000173926
BioGRIDMARCH3
STRING (EMBL)MARCH3
ZODIACMARCH3
Ontologies - Pathways
QuickGOQ86UD3
Ontology : AmiGOlysosome  endosome  endocytosis  zinc ion binding  integral component of membrane  protein ubiquitination  transferase activity  cytoplasmic vesicle membrane  early endosome membrane  
Ontology : EGO-EBIlysosome  endosome  endocytosis  zinc ion binding  integral component of membrane  protein ubiquitination  transferase activity  cytoplasmic vesicle membrane  early endosome membrane  
NDEx NetworkMARCH3
Atlas of Cancer Signalling NetworkMARCH3
Wikipedia pathwaysMARCH3
Orthology - Evolution
OrthoDB115123
GeneTree (enSembl)ENSG00000173926
Phylogenetic Trees/Animal Genes : TreeFam3-Mar
HOVERGENQ86UD3
HOGENOMQ86UD3
Homologs : HomoloGeneMARCH3
Homology/Alignments : Family Browser (UCSC)MARCH3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMARCH3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MARCH3
dbVarMARCH3
ClinVarMARCH3
1000_GenomesMARCH3 
Exome Variant ServerMARCH3
ExAC (Exome Aggregation Consortium)MARCH3 (select the gene name)
Genetic variants : HAPMAP115123
Genomic Variants (DGV)MARCH3 [DGVbeta]
DECIPHERMARCH3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMARCH3 
Mutations
ICGC Data Portal3-Mar 
TCGA Data Portal3-Mar 
Broad Tumor Portal3-Mar
OASIS Portal3-Mar [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMARCH3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMD3-Mar
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
BioMutasearch MARCH3
DgiDB (Drug Gene Interaction Database)MARCH3
DoCM (Curated mutations)MARCH3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MARCH3 (select a term)
intoGenMARCH3
Cancer3DMARCH3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613333   
Orphanet
MedgenMARCH3
Genetic Testing Registry MARCH3
NextProtQ86UD3 [Medical]
TSGene115123
GENETestsMARCH3
Target ValidationMARCH3
Huge Navigator 3-Mar [HugePedia]
snp3D : Map Gene to Disease115123
BioCentury BCIQMARCH3
ClinGenMARCH3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD115123
Chemical/Pharm GKB GenePA134901491
Clinical trialMARCH3
Miscellaneous
canSAR (ICR)MARCH3 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMARCH3
EVEXMARCH3
GoPubMedMARCH3
iHOPMARCH3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:26:57 CEST 2017

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