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MARCH5 (membrane associated ring-CH-type finger 5)

Identity

Alias_namesRNF153
ring finger protein 153
membrane-associated ring finger (C3HC4) 5
Alias_symbol (synonym)FLJ20445
MARCH-V
Other aliasMITOL
HGNC (Hugo) MARCH5
LocusID (NCBI) 54708
Atlas_Id 47489
Location 10q23.32  [Link to chromosome band 10q23]
Location_base_pair Starts at 92291163 and ends at 92353964 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MARCH5   26025
Cards
Entrez_Gene (NCBI)MARCH5  54708  membrane associated ring-CH-type finger 5
AliasesMARCH-V; MITOL; RNF153
GeneCards (Weizmann)MARCH5
Ensembl hg19 (Hinxton)ENSG00000198060 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198060 [Gene_View]  ENSG00000198060 [Sequence]  chr10:92291163-92353964 [Contig_View]  MARCH5 [Vega]
ICGC DataPortalENSG00000198060
TCGA cBioPortalMARCH5
AceView (NCBI)MARCH5
Genatlas (Paris)MARCH5
WikiGenes54708
SOURCE (Princeton)MARCH5
Genetics Home Reference (NIH)MARCH5
Genomic and cartography
GoldenPath hg38 (UCSC)MARCH5  -     chr10:92291163-92353964 +  10q23.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MARCH5  -     10q23.32   [Description]    (hg19-Feb_2009)
EnsemblMARCH5 - 10q23.32 [CytoView hg19]  MARCH5 - 10q23.32 [CytoView hg38]
Mapping of homologs : NCBIMARCH5 [Mapview hg19]  MARCH5 [Mapview hg38]
OMIM610637   
Gene and transcription
Genbank (Entrez)AB191202 AK000452 AK294799 AK309175 BC015480
RefSeq transcript (Entrez)NM_017824
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MARCH5
Cluster EST : UnigeneHs.573490 [ NCBI ]
CGAP (NCI)Hs.573490
Alternative Splicing GalleryENSG00000198060
Gene ExpressionMARCH5 [ NCBI-GEO ]   MARCH5 [ EBI - ARRAY_EXPRESS ]   MARCH5 [ SEEK ]   MARCH5 [ MEM ]
Gene Expression Viewer (FireBrowse)MARCH5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54708
GTEX Portal (Tissue expression)MARCH5
Human Protein AtlasENSG00000198060-MARCH5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NX47   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NX47  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NX47
Splice isoforms : SwissVarQ9NX47
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   
PhosPhoSitePlusQ9NX47
Domaine pattern : Prosite (Expaxy)ZF_RING_CH (PS51292)   
Domains : Interpro (EBI)MARCH-like    Znf_RING-CH    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)RINGv (PF12906)   
Domain families : Pfam (NCBI)pfam12906   
Domain families : Smart (EMBL)RINGv (SM00744)  
Conserved Domain (NCBI)MARCH5
DMDM Disease mutations54708
Blocks (Seattle)MARCH5
SuperfamilyQ9NX47
Human Protein Atlas [tissue]ENSG00000198060-MARCH5 [tissue]
Peptide AtlasQ9NX47
HPRD07909
IPIIPI00414168   
Protein Interaction databases
DIP (DOE-UCLA)Q9NX47
IntAct (EBI)Q9NX47
FunCoupENSG00000198060
BioGRIDMARCH5
STRING (EMBL)MARCH5
ZODIACMARCH5
Ontologies - Pathways
QuickGOQ9NX47
Ontology : AmiGOprotein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  mitochondrion  mitochondrial outer membrane  endoplasmic reticulum  endoplasmic reticulum membrane  zinc ion binding  membrane  integral component of membrane  GTPase binding  protein autoubiquitination  protein localization to mitochondrion  regulation of mitochondrial fission  positive regulation of mitochondrial fission  negative regulation of cell aging  
Ontology : EGO-EBIprotein polyubiquitination  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  mitochondrion  mitochondrial outer membrane  endoplasmic reticulum  endoplasmic reticulum membrane  zinc ion binding  membrane  integral component of membrane  GTPase binding  protein autoubiquitination  protein localization to mitochondrion  regulation of mitochondrial fission  positive regulation of mitochondrial fission  negative regulation of cell aging  
NDEx NetworkMARCH5
Atlas of Cancer Signalling NetworkMARCH5
Wikipedia pathwaysMARCH5
Orthology - Evolution
OrthoDB54708
GeneTree (enSembl)ENSG00000198060
Phylogenetic Trees/Animal Genes : TreeFamMARCH5
HOVERGENQ9NX47
HOGENOMQ9NX47
Homologs : HomoloGeneMARCH5
Homology/Alignments : Family Browser (UCSC)MARCH5
Gene fusions - Rearrangements
Fusion : QuiverMARCH5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMARCH5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MARCH5
dbVarMARCH5
ClinVarMARCH5
1000_GenomesMARCH5 
Exome Variant ServerMARCH5
ExAC (Exome Aggregation Consortium)ENSG00000198060
GNOMAD BrowserENSG00000198060
Varsome BrowserMARCH5
Genetic variants : HAPMAP54708
Genomic Variants (DGV)MARCH5 [DGVbeta]
DECIPHERMARCH5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMARCH5 
Mutations
ICGC Data PortalMARCH5 
TCGA Data PortalMARCH5 
Broad Tumor PortalMARCH5
OASIS PortalMARCH5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMARCH5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMARCH5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MARCH5
DgiDB (Drug Gene Interaction Database)MARCH5
DoCM (Curated mutations)MARCH5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MARCH5 (select a term)
intoGenMARCH5
Cancer3DMARCH5(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610637   
Orphanet
DisGeNETMARCH5
MedgenMARCH5
Genetic Testing Registry MARCH5
NextProtQ9NX47 [Medical]
TSGene54708
GENETestsMARCH5
Target ValidationMARCH5
Huge Navigator MARCH5 [HugePedia]
snp3D : Map Gene to Disease54708
BioCentury BCIQMARCH5
ClinGenMARCH5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54708
Chemical/Pharm GKB GenePA128394672
Clinical trialMARCH5
Miscellaneous
canSAR (ICR)MARCH5 (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMARCH5
EVEXMARCH5
GoPubMedMARCH5
iHOPMARCH5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:18:59 CET 2018

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