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MARCH7 (membrane associated ring-CH-type finger 7)

Identity

Alias_namesAXOT
axotrophin
membrane-associated ring finger (C3HC4) 7
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
Alias_symbol (synonym)MARCH-VII
RNF177
Other aliasAXO
HGNC (Hugo) MARCH7
LocusID (NCBI) 64844
Atlas_Id 56062
Location 2q24.2  [Link to chromosome band 2q24]
Location_base_pair Starts at 159712457 and ends at 159768583 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MARCH7 (2q24.2) / ERMARD (6q27)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)MARCH7   17393
Cards
Entrez_Gene (NCBI)MARCH7  64844  membrane associated ring-CH-type finger 7
AliasesAXO; AXOT; MARCH-VII; RNF177
GeneCards (Weizmann)MARCH7
Ensembl hg19 (Hinxton)ENSG00000136536 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000136536 [Gene_View]  chr2:159712457-159768583 [Contig_View]  MARCH7 [Vega]
ICGC DataPortalENSG00000136536
TCGA cBioPortalMARCH7
AceView (NCBI)MARCH7
Genatlas (Paris)MARCH7
WikiGenes64844
SOURCE (Princeton)MARCH7
Genetics Home Reference (NIH)MARCH7
Genomic and cartography
GoldenPath hg38 (UCSC)MARCH7  -     chr2:159712457-159768583 +  2q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MARCH7  -     2q24.2   [Description]    (hg19-Feb_2009)
EnsemblMARCH7 - 2q24.2 [CytoView hg19]  MARCH7 - 2q24.2 [CytoView hg38]
Mapping of homologs : NCBIMARCH7 [Mapview hg19]  MARCH7 [Mapview hg38]
OMIM613334   
Gene and transcription
Genbank (Entrez)AI863394 AK022973 AK124225 AK222880 AK292836
RefSeq transcript (Entrez)NM_001282805 NM_001282806 NM_001282807 NM_022826
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MARCH7
Cluster EST : UnigeneHs.529272 [ NCBI ]
CGAP (NCI)Hs.529272
Alternative Splicing GalleryENSG00000136536
Gene ExpressionMARCH7 [ NCBI-GEO ]   MARCH7 [ EBI - ARRAY_EXPRESS ]   MARCH7 [ SEEK ]   MARCH7 [ MEM ]
Gene Expression Viewer (FireBrowse)MARCH7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64844
GTEX Portal (Tissue expression)MARCH7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H992   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H992  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H992
Splice isoforms : SwissVarQ9H992
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   
PhosPhoSitePlusQ9H992
Domaine pattern : Prosite (Expaxy)ZF_RING_CH (PS51292)   
Domains : Interpro (EBI)Znf_RING-CH    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)RINGv (PF12906)   
Domain families : Pfam (NCBI)pfam12906   
Domain families : Smart (EMBL)RINGv (SM00744)  
Conserved Domain (NCBI)MARCH7
DMDM Disease mutations64844
Blocks (Seattle)MARCH7
SuperfamilyQ9H992
Human Protein AtlasENSG00000136536
Peptide AtlasQ9H992
HPRD09817
IPIIPI00010195   IPI00917960   IPI00917546   IPI00927814   
Protein Interaction databases
DIP (DOE-UCLA)Q9H992
IntAct (EBI)Q9H992
FunCoupENSG00000136536
BioGRIDMARCH7
STRING (EMBL)MARCH7
ZODIACMARCH7
Ontologies - Pathways
QuickGOQ9H992
Ontology : AmiGOregulation of tolerance induction  zinc ion binding  protein ubiquitination  transferase activity  negative regulation of T cell proliferation  
Ontology : EGO-EBIregulation of tolerance induction  zinc ion binding  protein ubiquitination  transferase activity  negative regulation of T cell proliferation  
NDEx NetworkMARCH7
Atlas of Cancer Signalling NetworkMARCH7
Wikipedia pathwaysMARCH7
Orthology - Evolution
OrthoDB64844
GeneTree (enSembl)ENSG00000136536
Phylogenetic Trees/Animal Genes : TreeFamMARCH7
HOVERGENQ9H992
HOGENOMQ9H992
Homologs : HomoloGeneMARCH7
Homology/Alignments : Family Browser (UCSC)MARCH7
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMARCH7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MARCH7
dbVarMARCH7
ClinVarMARCH7
1000_GenomesMARCH7 
Exome Variant ServerMARCH7
ExAC (Exome Aggregation Consortium)MARCH7 (select the gene name)
Genetic variants : HAPMAP64844
Genomic Variants (DGV)MARCH7 [DGVbeta]
DECIPHERMARCH7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMARCH7 
Mutations
ICGC Data PortalMARCH7 
TCGA Data PortalMARCH7 
Broad Tumor PortalMARCH7
OASIS PortalMARCH7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMARCH7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMARCH7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MARCH7
DgiDB (Drug Gene Interaction Database)MARCH7
DoCM (Curated mutations)MARCH7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MARCH7 (select a term)
intoGenMARCH7
Cancer3DMARCH7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613334   
Orphanet
MedgenMARCH7
Genetic Testing Registry MARCH7
NextProtQ9H992 [Medical]
TSGene64844
GENETestsMARCH7
Target ValidationMARCH7
Huge Navigator MARCH7 [HugePedia]
snp3D : Map Gene to Disease64844
BioCentury BCIQMARCH7
ClinGenMARCH7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64844
Chemical/Pharm GKB GenePA25198
Clinical trialMARCH7
Miscellaneous
canSAR (ICR)MARCH7 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMARCH7
EVEXMARCH7
GoPubMedMARCH7
iHOPMARCH7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:06:22 CEST 2017

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