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MARCHF1 (membrane associated ring-CH-type finger 1)

Identity

Alias (NCBI)MARCH-I
MARCH1
RNF171
HGNC (Hugo) MARCHF1
HGNC Alias symbFLJ20668
MARCH-I
RNF171
HGNC Previous name02-Mar
HGNC Previous namemembrane-associated ring finger (C3HC4) 1
 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
LocusID (NCBI) 55016
Atlas_Id 56895
Location 4q32.2-q32.3  [Link to chromosome band 4q32]
Location_base_pair Starts at 163524298 and ends at 163613534 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute



Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(4;4)(q21;q32) MARCH1/PTPN13


External links

Nomenclature
HGNC (Hugo)MARCHF1   26077
Cards
Entrez_Gene (NCBI)MARCHF1  55016  membrane associated ring-CH-type finger 1
AliasesMARCH-I; MARCH1; RNF171
GeneCards (Weizmann)MARCHF1
Ensembl hg19 (Hinxton)ENSG00000145416 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000145416 [Gene_View]  ENSG00000145416 [Sequence]  chr4:163524298-163613534 [Contig_View]  MARCHF1 [Vega]
ICGC DataPortalENSG00000145416
TCGA cBioPortalMARCHF1
AceView (NCBI)MARCHF1
Genatlas (Paris)MARCHF1
WikiGenes55016
SOURCE (Princeton)MARCHF1
Genetics Home Reference (NIH)MARCHF1
Genomic and cartography
GoldenPath hg38 (UCSC)MARCHF1  -     chr4:163524298-163613534 -  -   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MARCHF1  -     -   [Description]    (hg19-Feb_2009)
GoldenPathMARCHF1 - - [CytoView hg19]  MARCHF1 - - [CytoView hg38]
ImmunoBaseENSG00000145416
genome Data Viewer NCBIMARCHF1 [Mapview hg19]  
OMIM613331   
Gene and transcription
Genbank (Entrez)AK000675 AK025005 AK091335 AK289711 AK301408
RefSeq transcript (Entrez)NM_001166373 NM_017923
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MARCHF1
Alternative Splicing GalleryENSG00000145416
Gene ExpressionMARCHF1 [ NCBI-GEO ]   MARCHF1 [ EBI - ARRAY_EXPRESS ]   MARCHF1 [ SEEK ]   MARCHF1 [ MEM ]
Gene Expression Viewer (FireBrowse)MARCHF1 [ Firebrowse - Broad ]
GenevisibleExpression of MARCHF1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55016
GTEX Portal (Tissue expression)MARCHF1
Human Protein AtlasENSG00000145416-MARCHF1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TCQ1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TCQ1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TCQ1
Splice isoforms : SwissVarQ8TCQ1
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ8TCQ1
Domaine pattern : Prosite (Expaxy)ZF_RING_CH (PS51292)   
Domains : Interpro (EBI)Znf_RING-CH    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)RINGv (PF12906)   
Domain families : Pfam (NCBI)pfam12906   
Domain families : Smart (EMBL)RINGv (SM00744)  
Conserved Domain (NCBI)MARCHF1
DMDM Disease mutations55016
Blocks (Seattle)MARCHF1
SuperfamilyQ8TCQ1
Human Protein Atlas [tissue]ENSG00000145416-MARCHF1 [tissue]
Peptide AtlasQ8TCQ1
IPIIPI00382922   IPI00016724   IPI00965590   IPI00922039   IPI00965098   
Protein Interaction databases
DIP (DOE-UCLA)Q8TCQ1
IntAct (EBI)Q8TCQ1
FunCoupENSG00000145416
BioGRIDMARCHF1
STRING (EMBL)MARCHF1
ZODIACMARCHF1
Ontologies - Pathways
QuickGOQ8TCQ1
Ontology : AmiGOprotein polyubiquitination  protein polyubiquitination  protein polyubiquitination  antigen processing and presentation of peptide antigen via MHC class II  antigen processing and presentation of peptide antigen via MHC class II  cytoplasm  lysosome  lysosome  lysosomal membrane  endosome  endoplasmic reticulum membrane  plasma membrane  immune response  immune response  zinc ion binding  integral component of membrane  cytoplasmic vesicle membrane  early endosome membrane  early endosome membrane  late endosome membrane  late endosome membrane  trans-Golgi network membrane  MHC protein binding  MHC protein binding  ubiquitin protein ligase activity  ubiquitin protein ligase activity  
Ontology : EGO-EBIprotein polyubiquitination  protein polyubiquitination  protein polyubiquitination  antigen processing and presentation of peptide antigen via MHC class II  antigen processing and presentation of peptide antigen via MHC class II  cytoplasm  lysosome  lysosome  lysosomal membrane  endosome  endoplasmic reticulum membrane  plasma membrane  immune response  immune response  zinc ion binding  integral component of membrane  cytoplasmic vesicle membrane  early endosome membrane  early endosome membrane  late endosome membrane  late endosome membrane  trans-Golgi network membrane  MHC protein binding  MHC protein binding  ubiquitin protein ligase activity  ubiquitin protein ligase activity  
NDEx NetworkMARCHF1
Atlas of Cancer Signalling NetworkMARCHF1
Wikipedia pathwaysMARCHF1
Orthology - Evolution
OrthoDB55016
GeneTree (enSembl)ENSG00000145416
Phylogenetic Trees/Animal Genes : TreeFamMARCHF1
HOGENOMQ8TCQ1
Homologs : HomoloGeneMARCHF1
Homology/Alignments : Family Browser (UCSC)MARCHF1
Gene fusions - Rearrangements
Fusion : QuiverMARCHF1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMARCHF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MARCHF1
dbVarMARCHF1
ClinVarMARCHF1
1000_GenomesMARCHF1 
Exome Variant ServerMARCHF1
GNOMAD BrowserENSG00000145416
Varsome BrowserMARCHF1
Genetic variants : HAPMAP55016
Genomic Variants (DGV)MARCHF1 [DGVbeta]
DECIPHERMARCHF1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMARCHF1 
Mutations
ICGC Data PortalMARCHF1 
TCGA Data PortalMARCHF1 
Broad Tumor PortalMARCHF1
OASIS PortalMARCHF1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDMARCHF1
BioMutasearch MARCHF1
DgiDB (Drug Gene Interaction Database)MARCHF1
DoCM (Curated mutations)MARCHF1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MARCHF1 (select a term)
intoGenMARCHF1
Cancer3DMARCHF1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613331   
Orphanet
DisGeNETMARCHF1
MedgenMARCHF1
Genetic Testing Registry MARCHF1
NextProtQ8TCQ1 [Medical]
TSGene55016
GENETestsMARCHF1
Target ValidationMARCHF1
Huge Navigator MARCHF1 [HugePedia]
snp3D : Map Gene to Disease55016
BioCentury BCIQMARCHF1
ClinGenMARCHF1
Clinical trials, drugs, therapy
Protein Interactions : CTD55016
Clinical trialMARCHF1
Miscellaneous
canSAR (ICR)MARCHF1 (select the gene name)
HarmonizomeMARCHF1
DataMed IndexMARCHF1
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMARCHF1
EVEXMARCHF1
GoPubMedMARCHF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jul 16 15:22:14 CEST 2020

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