MARCHF9 (membrane associated ring-CH-type finger 9)

2018-11-01  

Identity

HGNC
MARCHF9
LOCATION
12q14.1
LOCUSID
92979
ALIAS
MARCH-IX,MARCH9,RNF179

Other Information

Locus ID:

NCBI: 92979
MIM: 613336
HGNC: 25139
Ensembl: ENSG00000139266

Variants:

dbSNP: 92979
ClinVar: 92979
TCGA: ENSG00000139266
COSMIC: MARCHF9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139266ENST00000266643Q86YJ5
ENSG00000139266ENST00000548358Q86YJ5

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
171743072007MARCH-IX mediates ubiquitination and downregulation of ICAM-1.25
208709412010Stress-regulated targeting of the NKG2D ligand Mult1 by a membrane-associated RING-CH family E3 ligase.17
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
285595422017MARCH9-mediated ubiquitination regulates MHC I export from the TGN.9
299216982018Computational Characterization of Suppressive Immune Microenvironments in Glioblastoma.7
302784502018MARCH9 Suppresses Lung Adenocarcinoma Progression by Downregulating ICAM-1.2
305541442019A serine in the first transmembrane domain of the human E3 ubiquitin ligase MARCH9 is critical for down-regulation of its protein substrates.2

Citation

Dessen P

MARCHF9 (membrane associated ring-CH-type finger 9)

Atlas Genet Cytogenet Oncol Haematol. 2018-11-01

Online version: http://atlasgeneticsoncology.org/gene/57665/marchf9