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MAST3 (microtubule associated serine/threonine kinase 3)

Identity

Alias_symbol (synonym)KIAA0561
Other alias-
HGNC (Hugo) MAST3
LocusID (NCBI) 23031
Atlas_Id 43354
Location 19p13.11  [Link to chromosome band 19p13]
Location_base_pair Starts at 18097793 and ends at 18151689 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CAV1 (7q31.2) / MAST3 (19p13.11)MAST3 (19p13.11) / EHMT2 (6p21.33)NR2F6 (19p13.11) / MAST3 (19p13.11)
PCYOX1 (2p13.3) / MAST3 (19p13.11)TBL1XR1 (3q26.32) / MAST3 (19p13.11)TBL1XR1 3q26.32 / MAST3 19p13.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  t(3;19)(q26;p13) TBL1XR1/MAST3
NR2F6/MAST3 (19p13)
t(19;20)(p13;p12) CDS2/MAST3


External links

Nomenclature
HGNC (Hugo)MAST3   19036
Cards
Entrez_Gene (NCBI)MAST3  23031  microtubule associated serine/threonine kinase 3
Aliases
GeneCards (Weizmann)MAST3
Ensembl hg19 (Hinxton)ENSG00000099308 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000099308 [Gene_View]  ENSG00000099308 [Sequence]  chr19:18097793-18151689 [Contig_View]  MAST3 [Vega]
ICGC DataPortalENSG00000099308
TCGA cBioPortalMAST3
AceView (NCBI)MAST3
Genatlas (Paris)MAST3
WikiGenes23031
SOURCE (Princeton)MAST3
Genetics Home Reference (NIH)MAST3
Genomic and cartography
GoldenPath hg38 (UCSC)MAST3  -     chr19:18097793-18151689 +  19p13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MAST3  -     19p13.11   [Description]    (hg19-Feb_2009)
MAST3 - 19p13.11 [CytoView hg19]  MAST3 - 19p13.11 [CytoView hg38]
Mapping of homologs : NCBIMAST3 [Mapview hg19]  MAST3 [Mapview hg38]
OMIM612258   
Gene and transcription
Genbank (Entrez)AB011133 BI907332 BQ340083 DA134568 DQ580260
RefSeq transcript (Entrez)NM_015016
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)MAST3
Cluster EST : UnigeneHs.466184 [ NCBI ]
CGAP (NCI)Hs.466184
Alternative Splicing GalleryENSG00000099308
Gene ExpressionMAST3 [ NCBI-GEO ]   MAST3 [ EBI - ARRAY_EXPRESS ]   MAST3 [ SEEK ]   MAST3 [ MEM ]
Gene Expression Viewer (FireBrowse)MAST3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23031
GTEX Portal (Tissue expression)MAST3
Human Protein AtlasENSG00000099308-MAST3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60307   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60307  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60307
Splice isoforms : SwissVarO60307
PhosPhoSitePlusO60307
Domaine pattern : Prosite (Expaxy)AGC_KINASE_CTER (PS51285)    PDZ (PS50106)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)AGC-kinase_C    Kinase-like_dom_sf    MA_Ser/Thr_Kinase_dom    MAST    MAST_pre-PK_dom_sf    PDZ    PDZ_sf    Prot_kinase_dom    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)DUF1908 (PF08926)    PDZ (PF00595)    Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam08926    pfam00595    pfam00069   
Domain families : Smart (EMBL)PDZ (SM00228)  S_TKc (SM00220)  
Conserved Domain (NCBI)MAST3
DMDM Disease mutations23031
Blocks (Seattle)MAST3
PDB (RSDB)1V9V    3KHF   
PDB Europe1V9V    3KHF   
PDB (PDBSum)1V9V    3KHF   
PDB (IMB)1V9V    3KHF   
Structural Biology KnowledgeBase1V9V    3KHF   
SCOP (Structural Classification of Proteins)1V9V    3KHF   
CATH (Classification of proteins structures)1V9V    3KHF   
SuperfamilyO60307
Human Protein Atlas [tissue]ENSG00000099308-MAST3 [tissue]
Peptide AtlasO60307
IPIIPI00028932   
Protein Interaction databases
DIP (DOE-UCLA)O60307
IntAct (EBI)O60307
FunCoupENSG00000099308
BioGRIDMAST3
STRING (EMBL)MAST3
ZODIACMAST3
Ontologies - Pathways
QuickGOO60307
Ontology : AmiGOmagnesium ion binding  protein serine/threonine kinase activity  protein binding  ATP binding  cytoskeleton organization  peptidyl-serine phosphorylation  intracellular signal transduction  
Ontology : EGO-EBImagnesium ion binding  protein serine/threonine kinase activity  protein binding  ATP binding  cytoskeleton organization  peptidyl-serine phosphorylation  intracellular signal transduction  
NDEx NetworkMAST3
Atlas of Cancer Signalling NetworkMAST3
Wikipedia pathwaysMAST3
Orthology - Evolution
OrthoDB23031
GeneTree (enSembl)ENSG00000099308
Phylogenetic Trees/Animal Genes : TreeFamMAST3
HOGENOMO60307
Homologs : HomoloGeneMAST3
Homology/Alignments : Family Browser (UCSC)MAST3
Gene fusions - Rearrangements
Fusion : MitelmanNR2F6/MAST3 [19p13.11/19p13.11]  [t(19;19)(p13;p13)]  
Fusion : MitelmanTBL1XR1/MAST3 [3q26.32/19p13.11]  [t(3;19)(q26;p13)]  
Fusion PortalTBL1XR1 3q26.32 MAST3 19p13.11 OV
Fusion : QuiverMAST3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMAST3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MAST3
dbVarMAST3
ClinVarMAST3
1000_GenomesMAST3 
Exome Variant ServerMAST3
ExAC (Exome Aggregation Consortium)ENSG00000099308
GNOMAD BrowserENSG00000099308
Varsome BrowserMAST3
Genetic variants : HAPMAP23031
Genomic Variants (DGV)MAST3 [DGVbeta]
DECIPHERMAST3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMAST3 
Mutations
ICGC Data PortalMAST3 
TCGA Data PortalMAST3 
Broad Tumor PortalMAST3
OASIS PortalMAST3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMAST3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDMAST3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch MAST3
DgiDB (Drug Gene Interaction Database)MAST3
DoCM (Curated mutations)MAST3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)MAST3 (select a term)
intoGenMAST3
Cancer3DMAST3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612258   
Orphanet
DisGeNETMAST3
MedgenMAST3
Genetic Testing Registry MAST3
NextProtO60307 [Medical]
TSGene23031
GENETestsMAST3
Target ValidationMAST3
Huge Navigator MAST3 [HugePedia]
snp3D : Map Gene to Disease23031
BioCentury BCIQMAST3
ClinGenMAST3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23031
Chemical/Pharm GKB GenePA134877725
Clinical trialMAST3
Miscellaneous
canSAR (ICR)MAST3 (select the gene name)
DataMed IndexMAST3
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineMAST3
EVEXMAST3
GoPubMedMAST3
iHOPMAST3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu May 2 12:57:15 CEST 2019

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