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MAST3 (microtubule associated serine/threonine kinase 3)

Identity

Alias (NCBI)-
HGNC (Hugo) MAST3
HGNC Alias symbKIAA0561
LocusID (NCBI) 23031
Atlas_Id 43354
Location 19p13.11  [Link to chromosome band 19p13]
Location_base_pair Starts at 18097778 and ends at 18151686 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CAV1 (7q31.2)::MAST3 (19p13.11)MAST3 (19p13.11)::EHMT2 (6p21.33)NR2F6 (19p13.11)::MAST3 (19p13.11)
PCYOX1 (2p13.3)::MAST3 (19p13.11)TBL1XR1 (3q26.32)::MAST3 (19p13.11)TBL1XR1 3q26.32::MAST3 19p13.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)MAST3   19036
Cards
Entrez_Gene (NCBI)MAST3    microtubule associated serine/threonine kinase 3
Aliases
GeneCards (Weizmann)MAST3
Ensembl hg19 (Hinxton)ENSG00000099308 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000099308 [Gene_View]  ENSG00000099308 [Sequence]  chr19:18097778-18151686 [Contig_View]  MAST3 [Vega]
ICGC DataPortalENSG00000099308
TCGA cBioPortalMAST3
AceView (NCBI)MAST3
Genatlas (Paris)MAST3
SOURCE (Princeton)MAST3
Genetics Home Reference (NIH)MAST3
Genomic and cartography
GoldenPath hg38 (UCSC)MAST3  -     chr19:18097778-18151686 +  19p13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MAST3  -     19p13.11   [Description]    (hg19-Feb_2009)
GoldenPathMAST3 - 19p13.11 [CytoView hg19]  MAST3 - 19p13.11 [CytoView hg38]
ImmunoBaseENSG00000099308
Genome Data Viewer NCBIMAST3 [Mapview hg19]  
OMIM612258   
Gene and transcription
Genbank (Entrez)AB011133 BI907332 BQ340083 DA134568 DQ580260
RefSeq transcript (Entrez)NM_001393501 NM_001393502 NM_001393503 NM_001393504 NM_001393505 NM_001393506 NM_001393507 NM_001393508 NM_001393509 NM_001393510 NM_001393511 NM_001393512 NM_001393513 NM_001393514 NM_001393515 NM_001393516 NM_001393517 NM_001393518 NM_001393519 NM_001393520 NM_001393521 NM_015016
Consensus coding sequences : CCDS (NCBI)MAST3
Gene ExpressionMAST3 [ NCBI-GEO ]   MAST3 [ EBI - ARRAY_EXPRESS ]   MAST3 [ SEEK ]   MAST3 [ MEM ]
Gene Expression Viewer (FireBrowse)MAST3 [ Firebrowse - Broad ]
GenevisibleExpression of MAST3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23031
GTEX Portal (Tissue expression)MAST3
Human Protein AtlasENSG00000099308-MAST3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60307   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60307  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60307
PhosPhoSitePlusO60307
Domaine pattern : Prosite (Expaxy)AGC_KINASE_CTER (PS51285)    PDZ (PS50106)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)AGC-kinase_C    Kinase-like_dom_sf    MA_Ser/Thr_Kinase_dom    MAST    MAST_pre-PK_dom_sf    PDZ    PDZ_6    PDZ_sf    Prot_kinase_dom    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)DUF1908 (PF08926)    PDZ_6 (PF17820)    Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam08926    pfam17820    pfam00069   
Domain families : Smart (EMBL)PDZ (SM00228)  S_TKc (SM00220)  
Conserved Domain (NCBI)MAST3
PDB (RSDB)1V9V    3KHF   
PDB Europe1V9V    3KHF   
PDB (PDBSum)1V9V    3KHF   
PDB (IMB)1V9V    3KHF   
Structural Biology KnowledgeBase1V9V    3KHF   
SCOP (Structural Classification of Proteins)1V9V    3KHF   
CATH (Classification of proteins structures)1V9V    3KHF   
SuperfamilyO60307
AlphaFold pdb e-kbO60307   
Human Protein Atlas [tissue]ENSG00000099308-MAST3 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)O60307
IntAct (EBI)O60307
BioGRIDMAST3
STRING (EMBL)MAST3
ZODIACMAST3
Ontologies - Pathways
QuickGOO60307
Ontology : AmiGOmagnesium ion binding  protein serine/threonine kinase activity  protein serine/threonine/tyrosine kinase activity  protein binding  ATP binding  cytoskeleton organization  peptidyl-serine phosphorylation  intracellular signal transduction  protein serine kinase activity  
Ontology : EGO-EBImagnesium ion binding  protein serine/threonine kinase activity  protein serine/threonine/tyrosine kinase activity  protein binding  ATP binding  cytoskeleton organization  peptidyl-serine phosphorylation  intracellular signal transduction  protein serine kinase activity  
NDEx NetworkMAST3
Atlas of Cancer Signalling NetworkMAST3
Wikipedia pathwaysMAST3
Orthology - Evolution
OrthoDB23031
GeneTree (enSembl)ENSG00000099308
Phylogenetic Trees/Animal Genes : TreeFamMAST3
Homologs : HomoloGeneMAST3
Homology/Alignments : Family Browser (UCSC)MAST3
Gene fusions - Rearrangements
Fusion : MitelmanNR2F6::MAST3 [19p13.11/19p13.11]  
Fusion : MitelmanTBL1XR1::MAST3 [3q26.32/19p13.11]  
Fusion : QuiverMAST3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMAST3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MAST3
dbVarMAST3
ClinVarMAST3
MonarchMAST3
1000_GenomesMAST3 
Exome Variant ServerMAST3
GNOMAD BrowserENSG00000099308
Varsome BrowserMAST3
ACMGMAST3 variants
VarityO60307
Genomic Variants (DGV)MAST3 [DGVbeta]
DECIPHERMAST3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMAST3 
Mutations
ICGC Data PortalMAST3 
TCGA Data PortalMAST3 
Broad Tumor PortalMAST3
OASIS PortalMAST3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMAST3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMAST3
Mutations and Diseases : HGMDMAST3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMAST3
DgiDB (Drug Gene Interaction Database)MAST3
DoCM (Curated mutations)MAST3
CIViC (Clinical Interpretations of Variants in Cancer)MAST3
Cancer3DMAST3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612258   
Orphanet
DisGeNETMAST3
MedgenMAST3
Genetic Testing Registry MAST3
NextProtO60307 [Medical]
GENETestsMAST3
Target ValidationMAST3
Huge Navigator MAST3 [HugePedia]
ClinGenMAST3
Clinical trials, drugs, therapy
MyCancerGenomeMAST3
Protein Interactions : CTDMAST3
Pharm GKB GenePA134877725
PharosO60307
Clinical trialMAST3
Miscellaneous
canSAR (ICR)MAST3
HarmonizomeMAST3
ARCHS4MAST3
DataMed IndexMAST3
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMAST3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Jan 20 12:43:24 CET 2022

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