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MAST4 (microtubule associated serine/threonine kinase family member 4)

Identity

Alias (NCBI)-
HGNC (Hugo) MAST4
HGNC Alias symbKIAA0303
LocusID (NCBI) 375449
Atlas_Id 43355
Location 5q12.3  [Link to chromosome band 5q12]
Location_base_pair Starts at 66596393 and ends at 66986523 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
IFT80 (3q25.33) / MAST4 (5q12.3)MAST4 (5q12.3) / ABR (17p13.3)MAST4 (5q12.3) / COL12A1 (6q13)
MAST4 (5q12.3) / MAST4 (5q12.3)MAST4 (5q12.3) / MRPS27 (5q13.2)MAST4 (5q12.3) / NLN (5q12.3)
NDUFAF2 (5q12.1) / MAST4 (5q12.3)MAST4 5q12.3 / MRPS27 5q13.2MAST4 5q12.3 / NLN 5q12.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)MAST4   19037
Cards
Entrez_Gene (NCBI)MAST4    microtubule associated serine/threonine kinase family member 4
Aliases
GeneCards (Weizmann)MAST4
Ensembl hg19 (Hinxton)ENSG00000069020 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000069020 [Gene_View]  ENSG00000069020 [Sequence]  chr5:66596393-66986523 [Contig_View]  MAST4 [Vega]
ICGC DataPortalENSG00000069020
TCGA cBioPortalMAST4
AceView (NCBI)MAST4
Genatlas (Paris)MAST4
SOURCE (Princeton)MAST4
Genetics Home Reference (NIH)MAST4
Genomic and cartography
GoldenPath hg38 (UCSC)MAST4  -     chr5:66596393-66986523 +  5q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)MAST4  -     5q12.3   [Description]    (hg19-Feb_2009)
GoldenPathMAST4 - 5q12.3 [CytoView hg19]  MAST4 - 5q12.3 [CytoView hg38]
ImmunoBaseENSG00000069020
Genome Data Viewer NCBIMAST4 [Mapview hg19]  
OMIM618002   
Gene and transcription
Genbank (Entrez)AB002301 AK057601 AK131421 AK296707 AK299538
RefSeq transcript (Entrez)NM_001164664 NM_001290226 NM_001290227 NM_001290228 NM_001297651 NM_001393524 NM_001393525 NM_001393526 NM_001393527 NM_001393528 NM_015183 NM_198828
Consensus coding sequences : CCDS (NCBI)MAST4
Gene ExpressionMAST4 [ NCBI-GEO ]   MAST4 [ EBI - ARRAY_EXPRESS ]   MAST4 [ SEEK ]   MAST4 [ MEM ]
Gene Expression Viewer (FireBrowse)MAST4 [ Firebrowse - Broad ]
GenevisibleExpression of MAST4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)375449
GTEX Portal (Tissue expression)MAST4
Human Protein AtlasENSG00000069020-MAST4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15021   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15021  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15021
PhosPhoSitePlusO15021
Domaine pattern : Prosite (Expaxy)AGC_KINASE_CTER (PS51285)    PDZ (PS50106)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)AGC-kinase_C    Kinase-like_dom_sf    MA_Ser/Thr_Kinase_dom    MAST    MAST_pre-PK_dom_sf    PDZ    PDZ_6    PDZ_sf    Prot_kinase_dom    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)DUF1908 (PF08926)    PDZ_6 (PF17820)    Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam08926    pfam17820    pfam00069   
Domain families : Smart (EMBL)PDZ (SM00228)  S_TKc (SM00220)  
Conserved Domain (NCBI)MAST4
PDB (RSDB)2W7R   
PDB Europe2W7R   
PDB (PDBSum)2W7R   
PDB (IMB)2W7R   
Structural Biology KnowledgeBase2W7R   
SCOP (Structural Classification of Proteins)2W7R   
CATH (Classification of proteins structures)2W7R   
SuperfamilyO15021
AlphaFold pdb e-kbO15021   
Human Protein Atlas [tissue]ENSG00000069020-MAST4 [tissue]
HPRD14195
Protein Interaction databases
DIP (DOE-UCLA)O15021
IntAct (EBI)O15021
BioGRIDMAST4
STRING (EMBL)MAST4
ZODIACMAST4
Ontologies - Pathways
QuickGOO15021
Ontology : AmiGOmagnesium ion binding  protein serine/threonine kinase activity  ATP binding  cytoplasm  cytoskeleton organization  peptidyl-serine phosphorylation  intracellular signal transduction  protein serine kinase activity  protein threonine kinase activity  
Ontology : EGO-EBImagnesium ion binding  protein serine/threonine kinase activity  ATP binding  cytoplasm  cytoskeleton organization  peptidyl-serine phosphorylation  intracellular signal transduction  protein serine kinase activity  protein threonine kinase activity  
NDEx NetworkMAST4
Atlas of Cancer Signalling NetworkMAST4
Wikipedia pathwaysMAST4
Orthology - Evolution
OrthoDB375449
GeneTree (enSembl)ENSG00000069020
Phylogenetic Trees/Animal Genes : TreeFamMAST4
Homologs : HomoloGeneMAST4
Homology/Alignments : Family Browser (UCSC)MAST4
Gene fusions - Rearrangements
Fusion : MitelmanERBB2IP/MAST4 [5q12.3/5q12.3]  
Fusion : MitelmanMAST4/MRPS27 [5q12.3/5q13.2]  
Fusion : MitelmanMAST4/NLN [5q12.3/5q12.3]  
Fusion : MitelmanNDUFAF2/MAST4 [5q12.1/5q12.3]  
Fusion : QuiverMAST4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerMAST4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)MAST4
dbVarMAST4
ClinVarMAST4
MonarchMAST4
1000_GenomesMAST4 
Exome Variant ServerMAST4
GNOMAD BrowserENSG00000069020
Varsome BrowserMAST4
ACMGMAST4 variants
VarityO15021
Genomic Variants (DGV)MAST4 [DGVbeta]
DECIPHERMAST4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisMAST4 
Mutations
ICGC Data PortalMAST4 
TCGA Data PortalMAST4 
Broad Tumor PortalMAST4
OASIS PortalMAST4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICMAST4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DMAST4
Mutations and Diseases : HGMDMAST4
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaMAST4
DgiDB (Drug Gene Interaction Database)MAST4
DoCM (Curated mutations)MAST4
CIViC (Clinical Interpretations of Variants in Cancer)MAST4
Cancer3DMAST4
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM618002   
Orphanet
DisGeNETMAST4
MedgenMAST4
Genetic Testing Registry MAST4
NextProtO15021 [Medical]
GENETestsMAST4
Target ValidationMAST4
Huge Navigator MAST4 [HugePedia]
ClinGenMAST4
Clinical trials, drugs, therapy
MyCancerGenomeMAST4
Protein Interactions : CTDMAST4
Pharm GKB GenePA134920494
PharosO15021
Clinical trialMAST4
Miscellaneous
canSAR (ICR)MAST4
HarmonizomeMAST4
DataMed IndexMAST4
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXMAST4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:17:56 CEST 2021

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