Atlas of Genetics and Cytogenetics in Oncology and Haematology

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MAX (MYC associated factor X)

Identity

Other namesbHLHd4
HGNC (Hugo) MAX
LocusID (NCBI) 4149
Location 14q23.3
Location_base_pair Starts at 65550457 and ends at 65569262 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)MAX   6913
Entrez_Gene (NCBI)MAX  4149  MYC associated factor X
Cards
GeneCards (Weizmann)MAX
Ensembl (Hinxton)ENSG00000125952 [Gene_View]  chr14:65550457-65569262 [Contig_View]  MAX [Vega]
AceView (NCBI)MAX
Genatlas (Paris)MAX
SOURCE (Stanford)NM_001271068 NM_001271069 NM_002382 NM_145112 NM_145113 NM_145114 NM_145116 NM_197957
Genomic and cartography
GoldenPath (UCSC)MAX  -  14q23.3   chr14:65550457-65569262 -  14q23.3   [Description]    (hg19-Feb_2009)
EnsemblMAX - 14q23.3 [CytoView]
Mapping of homologs : NCBIMAX [Mapview]
OMIM154950   171300   
Gene and transcription
Genbank (Entrez)AI652319 AI655674 AI769390 AI917842 AI954328
RefSeq transcript (SRS)NM_001271068 NM_001271069 NM_002382 NM_145112 NM_145113 NM_145114 NM_145116 NM_197957
RefSeq transcript (Entrez)NM_001271068 NM_001271069 NM_002382 NM_145112 NM_145113 NM_145114 NM_145116 NM_197957
RefSeq genomic (SRS)AC_000146 NC_000014 NC_018925 NG_029830 NT_026437 NW_001838111 NW_004078079
RefSeq genomic (Entrez)AC_000146 NC_000014 NC_018925 NG_029830 NT_026437 NW_001838111 NW_004078079
Consensus coding sequences : CCDS (NCBI)MAX
Cluster EST : UnigeneHs.285354 [ SRS ] Hs.285354 [ NCBI ]
CGAP (NCI)Hs.285354
Alternative Splicing : Fast-db (Paris)GSHG0009428
Alternative Splicing GalleryENSG00000125952
Gene ExpressionMAX [ NCBI-GEO ]   MAX [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP61244 (SRS) P61244 (Uniprot)
NextProtP61244
With graphics : InterProP61244
Splice isoforms : SwissVarP61244(Swissvar)
Domaine pattern : Prosite (SRS)BHLH (PS50888)   
Domaine pattern : Prosite (Expaxy)BHLH (PS50888)   
Domains : Interpro (SRS)HLH_dom   
Domains : Interpro (EBI)HLH_dom   
Related proteins : CluSTrP61244
Domain families : Pfam (SRS)HLH (PF00010)   
Domain families : Pfam (Sanger)HLH (PF00010)   
Domain families : Pfam (NCBI)pfam00010   
Domain families : Smart (EMBL)HLH (SM00353)  
DMDM4149
Blocks (Seattle)P61244
PDB (SRS)1AN2    1HLO    1NKP    1NLW    1R05   
PDB (PDBSum)1AN2    1HLO    1NKP    1NLW    1R05   
PDB (IMB)1AN2    1HLO    1NKP    1NLW    1R05   
PDB (RSDB)1AN2    1HLO    1NKP    1NLW    1R05   
Human Protein AtlasENSG00000125952
HPRD01113
IPIIPI00018214   IPI00219929   IPI00158128   IPI00910746   IPI01024818   IPI01026513   IPI01026141   IPI00978532   IPI01025079   IPI01024945   IPI01025539   IPI00377126   IPI00157813   IPI00060723   
Protein Interaction databases
DIP (DOE-UCLA)P61244
IntAct (EBI)P61244
FunCoupENSG00000125952
REACTOMEMAX
Protein Interaction Database4149
BioGRIDMAX
InParanoidP61244
Interologous Interaction database P61244
IntegromeDBMAX
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)MAX
SNP (GeneSNP Utah)MAX
SNP : HGBaseMAX
Genetic variants : HAPMAPMAX
Somatic Mutations in Cancer : COSMICMAX 
CONAN: Copy Number AnalysisMAX 
Mutations and Diseases : HGMDMAX
OMIM154950    171300   
GENETests154950    171300   
Disease Genetic AssociationMAX
Huge Navigator MAX [HugePedia]  MAX [HugeCancerGEM]
Genomic VariantsMAX  MAX [DGVbeta]
snp3D : Map Gene to Disease4149
General knowledge
Homologs : HomoloGeneMAX
Homology/Alignments : Family Browser (UCSC)MAX
Phylogenetic Trees/Animal Genes : TreeFamMAX
Chemical/Protein Interactions : CTD4149
Chemical/Pharm GKB GenePA30656
Clinical trialMAX
Cancer Resource (Charite)ENSG00000125952
Ontology : AmiGOsequence-specific DNA binding transcription factor activity  transcription cofactor activity  transcription coactivator activity  protein binding  nucleus  nucleolus  cytoplasm  transcription from RNA polymerase II promoter  protein complex assembly  cellular response to starvation  negative regulation of gene expression  PML body  dendrite  protein complex binding  response to insulin stimulus  protein homodimerization activity  sequence-specific DNA binding  protein heterodimerization activity  response to axon injury  neuron apoptotic process  retina development in camera-type eye  MLL1 complex  cellular response to peptide hormone stimulus  
Ontology : EGO-EBIsequence-specific DNA binding transcription factor activity  transcription cofactor activity  transcription coactivator activity  protein binding  nucleus  nucleolus  cytoplasm  transcription from RNA polymerase II promoter  protein complex assembly  cellular response to starvation  negative regulation of gene expression  PML body  dendrite  protein complex binding  response to insulin stimulus  protein homodimerization activity  sequence-specific DNA binding  protein heterodimerization activity  response to axon injury  neuron apoptotic process  retina development in camera-type eye  MLL1 complex  cellular response to peptide hormone stimulus  
Pathways : BIOCARTAp38 MAPK Signaling Pathway [Genes]    Overview of telomerase protein component gene hTert Transcriptional Regulation [Genes]    MAPKinase Signaling Pathway [Genes]   
Pathways : KEGGMAPK signaling pathway
Other databases
Probes
Litterature
PubMed104 Pubmed reference(s) in Entrez
PubGeneMAX
iHOPMAX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:46:31 CEST 2013
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